A386G polymorphism of the DAZL gene is not associated with idiopathic male infertility in North India

Journal of Human Reproductive Sciences

Volumn 2, Issue 2, 2009, Pages 54-56

  Singh, Kiran ^a   Raman, Rajiva ^a  

^a BANARAS HINDU UNIVERSITY   (India)

Author keywords

A386G polymorphism; Azoospermia; DAZL gene; Infertility; Y chromosome microdeletion

Indexed keywords

ALANINE; GLYCINE; RNA BINDING PROTEIN; RNA BINDING PROTEIN DAZL; UNCLASSIFIED DRUG;

ADULT; AMINO ACID SUBSTITUTION; AMPLICON; ARTICLE; AZOOSPERMIA; CASE CONTROL STUDY; CONTROLLED STUDY; GENE EXPRESSION; GENE MUTATION; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; IDIOPATHIC MALE INFERTILITY; INDIA; MAJOR CLINICAL STUDY; MALE; MALE FERTILITY; MALE INFERTILITY; OLIGOSPERMIA; POLYMERASE CHAIN REACTION; PREVALENCE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 77953404464     PISSN: 09741208     EISSN: 19984766     Source Type: Journal    
DOI: 10.4103/0974-1208.57222     Document Type: Article

References (10)

1. Krausz C, Quintana-Murci L, Rajpert-De Meyts E, Jorgensen N, Jobling MA, Rosser ZH, et al. Identification of a Y chromosome haplogroup associated with reduced sperm counts. Hum Mol Genet 2001;10:1873-1877
2. Matzuk MM, Lamb DJ. Genetic dissection of mammalian fertility pathways. Nat Cell Biol Nat Med 2002;41-49
3. Singh K, Singh SK, Sah R, Singh I, Raman R. Mutation C677T in the methylenetetrahydrofolate reductase gene is associated with male infertility in an Indian population. Int J Androl 2005;28:115-119
4. Ebisch IM, van Heerde WL, Thomas CM, van der Put NS, Wong WY, Steegers-Theunissen RP. C677T methylenetetrahydrofolate reductase polymorphism interferes with the effects of folic acid and zinc sulfate on sperm concentration. Fertil Steril 2003;80:1190-1194
5. Saxena R, Brown LG, Hawkins T, Alagappan RK, Skaletsky H, Reeve MP, et al. The DAZ gene cluster on the human Y chromosome arose from an autosomal gene that was transposed, repeatedly amplified and pruned. Nat Genet 1996;14:292-299
6. Slee R, Grimes B, Speed RM, Taggart M, Maguire SM, Ross A, et al. A human DAZ transgene confers partial rescue of the mouse DAZL null phenotype. Proc Natl Acad Sci USA 1999;96:8040-8045
7. Teng YN, Lin YM, Lin YH, Tsao SY, Hsu CC, Lin SJ, et al. Association of a single-nucleotide polymorphism of the deleted-in-azoospermia-like gene with susceptibility to spermatogenic failure. J Clin Endocrinol Metab 2002;87:5258-5264
8. Bartoloni L, Cazzadre A, Ferlin A, Garolla A, Foresta C. Lack of the T54A polymorphism of the DAZL gene in infertile Italian patients. Mol Hum Reprod 2004;10:613-615
9. Poongothai J, Gopenath TS, Manonayaki S. A386G transition in DAZL gene is not associated with spermatogenic failure in Tamil Nadu, South India. Indian J Hum Genet 2008;14:16-19
10. Thangraj K, Deepa SR, Pavai K, Gupta NJ, Reddy P, Reddy AG, et al. A to G transitions at 260, 386 and 437 in DAZL gene are not associated with spermatogenic failure in Indian population. Int J Androl 2006;29:510-514