Comparative evaluation of in vitro diclofenac sodium permeability across excised mouse skin from different common pharmaceutical vehicles

International Journal of PharmTech Research

Volumn 2, Issue 1, 2010, Pages 920-930

  Nayak, Amit Kumar ^a   Mohanty, Biswaranjan ^b   Sen, Kalyan Kumar ^a  

^a GUPTA COLLEGE OF TECHNOLOGICAL SCIENCES   (India)

^b SEEMANTA INSTITUTE OF PHARMACEUTICAL SCIENCES   (India)

Author keywords

Diclofenac sodium; In vitro; Permeation enhancer; Skin permeation; Vehicles

Indexed keywords

ALOE VERA EXTRACT; ARACHIS OIL; CARBOXYMETHYLCELLULOSE; CASTOR OIL; DICLOFENAC; LIQUID PARAFFIN; MENTHOL; MYRISTIC ACID ISOPROPYL ESTER; OLIVE OIL; PENETRATION ENHANCING AGENT;

ANIMAL TISSUE; ARTICLE; COMPARATIVE STUDY; DIFFUSION COEFFICIENT; DRUG EFFECT; DRUG SOLUBILITY; IN VITRO STUDY; MOUSE; NONHUMAN; PARTITION COEFFICIENT; SKIN PERMEABILITY;

EID: 77953385022     PISSN: None     EISSN: 09744304     Source Type: Journal    
DOI: None     Document Type: Article

References (33)

1. Sawynok J., Topical and peripherally acting anagescics, Pharmacol. Rev., 2003, 55, 1-20.
2. Saqueira J.A., Optimization of the skin availability of topical products, Cosmet. Toilet., 1990, 105, 114-121.
3. Pithayanukul P., Chansri N., and Sugibayashi K., The enhancing effects of common pharmaceutical solvents on the in vitro skin permeation of estradiol, Thai. J. Pharm. Sci., 2002, 26 (3-4), 109-119.
4. Mortazavi S.A., and Aboofazeli R., An investigation into the effect of various penetration enhancers on percutaneous absorption of piroxicam, Iranian. J. Pharm. Res., 2003, 2, 135-140.
5. Nagwhirunpat T., Opanasopit P., Panomsuk S., Rojanarata T., and Kumprakrob U., Skin permeation enhancement of ketoprofen supersaturated solution with antinucleant polymers, Thai. J. Pharm. Sci., 2005, 29(1-2), 11-19.
6. Langer R., Transdermal drug delivery: past progress, current status and future prospects, Adv. Drug. Del. Rev., 2004, 56, 557-558.
7. Al-Suwayeh S.A., Transdermal delivery of isradipine through excised rabbit skin: Effect of vehicle and drug concentration, Saudi. Pharm. J., 2003, 11(1-2), 46-51.
8. Kesavanarayanan K.S., Nappinnai H., and Ilavarsan R., Topical dosage form of valdecoxib: Preparation and pharmacological evaluation, Acta. Pharm., 2007, 57, 199-209.
9. Gülgün Yener G., Dal Ö., and Üner M., Effect of vehicles on release of meloxicam from various topical formulations, Open. Drug. Deliv., 2009, 3, 19-23.
10. Mollgaard B., and Hoelgaard A., Vehicle effect on topical drug delivery: II. Concurrent skin transport of drugs and vehicle components, Acta. Pharm. Suec., 1983, 20, 443-450.
11. Cross S.E., Pugh W.J., Hadgarft J., and Roberts M.S., Probing the effect of vehicle, Int. J. Pharm., 1995, 114, 75-83.
12. Nayak A.S., Jain A. Rathore P., Sumbhate S., and Nayak S., A comparative study of lisinopril from different vehicles. Int. J. Pharm. Pharmceut. Sci., 2009, 1(1), 213-218.
13. El Maghraby G.M., Alanazi F.K., and Alsarra I.A.. Transdermal delivery of tadalafil. I. Effect of vehicles on skin permeation, Drug. Deliv. Ind. Pharm., 2009, 35(3), 329-336.
14. Harada S., Takahashi Y., Nakagawa H., Yamashita F., and Hashida M., Effect of vehicle properties on skin penetration of emedastine, Biol. Pharm. Bull., 2000, 23(10), 1224-1228.
15. Kantarci G., Ozguency I., Karasulu H.Y., Arzik S., and Guneri T., Comparison of different water/oil microemulsions containing diclofenac sodium: Preparation, characterization, release rate and skin irritation studies, AAPS. PharmSciTech., 2007, 8(4), Article 91.
16. Chowdary K.P.R., Mohapatra P., and Murali Krishna M.N., Evaluation of olibanum and its resin as rate controlling matrix for controlled release of diclofenac, Indian. J. Pharm. Sci., 2009, 68(4), 497-500.
17. Takahashi K., Tamagawa S., Katagi T., Yoshitomi H., Kamada A., Rytting J.H., Nishihata T., and Mizuno N., In vitro transport of sodium diclofenac across rat abdominal skin: Effect of selection of oleaginous component and the addition of alcohols to the vehicle, Chem. Pharm. Bull., 1991, 39(1), 154-158.
18. Takahashi K., Suzuki T., Sakano H., and Mizuno N., Effect of vehicles of diclofenac permeation across excised rat skin, Biol. Pharm. Bull., 1995, 18(4), 571-575.
19. Vanna S., Alessandra T., and Bario D.L., Effect of vehicle on diclofenac sodium permeation from new topical formulation: In vitro and in vivo studies, Curr. Drug. Deliv., 2009, 6(1), 93-100.
20. Durrhim H., Flynn G.L., Higuchi W.I., and Behl C.R., Permeation of hairless mouse skin I: experimental method and comparison with human epidermal permeation by alkanol, J. Pharm. Sci., 1980, 69, 781-786.
21. Barry B.W., Dermatological Formulations: Percutaneous absorption, Marcel Dekker Inc., New York, 1983, 49-94.
22. Shah J.C., Analysis of permeation data: evaluation of lag time method, Int. J. Pharm., 1993, 90, 161-169.
23. Aslani P., and Kennedy R.A., Studies on diffusion in alginate gels I. Effect of cross-linking with calcium or zinc ion diffusion of acetaminophen, J. Control. Release., 1996, 42, 75-82.
24. Pefile S.C., Smith E.W., Albrecht C.F., and Kruger P.B., Release of rooperol tetra-acetate from topical bases: in vitro studies using silicon membrane, J. Control. Release., 1998, 161, 237-243.
25. Sato A., Friend O., and Nagni I., Effect and mode of action of aliphatic esters, Int. J. Pharm., 1988, 43, 31-40.
26. Ahuja M., Sharma S.K., and Majumder D.K., In-vitro corneal permeation of diclofenac from oil drops, Yakugaku. Zasshi., 2007, 17, 1739-1749.
27. Pathan I.B., and Setty C.M., Chemical penetration enhancers for transdermal drug delivery systems, Trop. J. Pharm. Res., 2009, 8(2), 173-179.
28. El-Kuttan A.F., Asbill C.S., and Michniak B.B., The effect of terpenes enhancer lipophilicity on the percutaneuos permeation of hydrocortisone formulated in HPMC gel system, Int. J. Pharm., 2000, 198, 179-189.
29. Jain A.K., Thomas N.S., and Panchangnula R., Transdermal drug delivery of imipramine hydrochloride. I. Effect of terpenes, J. Control. Release., 2002, 79, 93-101.
30. Sinha V.R., and Kaur M.P., Permeation enhancer for transdermal drug delivery, Drug. Dev. Ind. Pharm., 2000, 26(11), 1131-1140.
31. Maitani Y., Shimada K., and Nagai T., l-Menthol, oleic acid and lauricidin in absorption enhancement of free and sodium salt of diclofenac using ethanol treated silicone membrane as model for skin, Chem. Pharm. Bull., 1996, 44, 403-408.
32. Louise C., and Charles H., Skin permeation enhancement potential of Aloe vera and a proposed mechanism of action based upon size exclusion and pull effect, Int. J. Pharm., 2007, 333, 10-16.
33. Gannu R., Vishnu Yamsani V., and Rao Yamsani M., Enhancement potential of Aloe vera on permeation of drugs with diverse lipophilicities across rat abdominal skin. Curr Trends Biotechnol Pharm, 2008, 2(4), 548-554.