A validated normal phase HPLC method for simultaneous determination of drotaverine hydrochloride and omeprazole in pharmaceutical formulation

Asian Journal of Pharmaceutical and Clinical Research

Volumn 3, Issue 1, 2010, Pages 20-24

  Topagi, Kirti S ^a   Jeswani, Rajesh M ^a   Sinha, Purushotam K ^a   Damle, Mrinalini C ^a  

^a AISSMS COLLEGE OF PHARMACY   (India)

Author keywords

Drotaverine hydrochloride; Normal phase HPLC; Omeprazole

Indexed keywords

AMMONIA; DICHLOROMETHANE; DROTAVERINE; DROTAVERINE HYDROCHLORIDE PLUS OMEPRAZOLE; EXCIPIENT; HEPTANE; LACTOSE; MAGNESIUM STEARATE; METHANOL; METHANOL DERIVATIVE; OMEPRAZOLE; STARCH; UNCLASSIFIED DRUG;

ACCURACY; ARTICLE; DRUG DETERMINATION; DRUG FORMULATION; DRUG SPECIFICITY; FLOW RATE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; PHASE TRANSITION; TABLET FORMULATION; ULTRAVIOLET RADIATION; VALIDATION STUDY;

EID: 77953377744     PISSN: 09742441     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (25)

1. th ed, New Jersey: Merck, Whitehouse Station, 2001, p. 3489.
2. Chitlange SS, Ranjana S, Wankhede SB, Kulkarni AA. Spectrophotometric methods for simultaneous estimation of nimesulide and drotaverine. Intern. J of Chem Tech Research 2009; 1: 135-138.
3. Stenhoff H, Blomqvist A, Lagerstrom PO. Determination of the enantiomers of omeprazole in blood plasma by normal-phase liquid chromatography and detection by a atmospheric pressure ionization tandem mass spectrometry. J. of Chromatography B 1999; 734: 191-201.
4. The United States Pharmacopoeia, Asian edition, Rockville, MD: USP Convention Rockville, MD, USP Convention Inc, 2007, p.2796-2798.
5. Indian Pharmacopoeia, Volume II, Published by the controller of Publication, Delhi, 2007, 1473-1475.
6. Abdellatef HE, Ayad MM, Soliman SM, Youssef NF. Spectrophotometric and spectrodensitometric determination of paracetamol and drotaverine HCl in combination. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2007; 66: 1147-1151.
7. Metwally FH. Simultaneous determination of nifuroxazide and drotaverine hydrochloride in pharmaceutical preparations by bivariate and multivariate spectral analysis. Spectrochimica acta. Part A, Molecular and biomolecular spectroscopy 2008; 69: 343-349.
8. Dahivelkar PP, Mahajan VK, Bari SB, Shirkhedkar AA, Fursule RA, Surana SJ. Simultaneous derivative and multicomponent spectrophotometric determination of drotaverine hydrochloride and mefenamic acid in tablets. Indian J of Pharm Sci 2007; 69: 812-814.
9. Bolaji OO, Onyeji CO, Ogungbamila FO, Ogunbona FA, Ogunlana EO. High-performance liquid chromatographic method for the determination of drotaverine in human plasma and urine. J. of Chromatogr: Biomed Appl 1993; 622: 93-97.
10. Lalla JK, Shah MU, Jain MB, Sharma AH. Modified high-performance liquid chromatographic method for analysis of drotaverine in human plasma. J. of Pharm. Biomed. Anal 1993; 11: 385-388.
11. Mezei J, Kuttel S, Szentmiklosi P, Marton S, Racz I. A new method for high-performance liquid chromatographic determination of drotaverine in plasma. J. of Pharm Sci. 2006; 73: 1489-1491.
12. Ayad MM, Youssef NF, Abdellatif HE, Soliman SM. A comparative study on various spectrometries with thin layer chromatography for simultaneous analysis of drotaverine and nifuroxazide in capsules. Chemical and Pharma Bull 2006; 54: 6807.
13. Metwally FH, Abdelkawy M, Naguib IA Determination of nifuroxazide and drotaverine hydrochloride in pharmaceutical preparations by three independent analytical methods. J. of AOAC Intern. 2006; 89: 78-87.(HPTLC, Spectro, HPLC)
14. Ziyatdinova GK, Samigullin AI, Budnikov GK Voltammetric determination of papaverine and drotaverine. J. of Anal. Chem. 2007; 62: 773-776.
15. Dubuc MC, Hamel C, Caubet MS, Brazier JL A rapid HPLC-DAD method for separation and determination of omeprazole extracted from human plasma. J. of liq. chromatogr & related tech 2001; 24: 1161-1169.
16. El-Sherif ZA, Mohamed AO, El-Bardicy MG, El-Tarras MF Reversed-Phase High Performance Liquid Chromatographic Method for the Determination of Lansoprazole, Omeprazole and Pantoprazole Sodium Sesquihydrate in Presence of Their Acid-Induced Degradation Products. Chem. & Pharm Bull 2006; 54: 6814.
17. Murakami FS, Cruz AP, Pereira RN, Valente BR, Silva MAS, Development and validation of a RP-HPLC method to quantify omeprazole in delayed release tablets. J of liq chromgr. & related tech 2007; 30: 113-121.
18. Sivasubramanian L, Anilkumar V Simultaneous HPLC estimation of omeprazole and domperidone from tablets. Indian J. of pharm sci. 2007; 69: 674-676.
19. Sluggett GW, Stong JD, Adams JH, Zhao Z Omeprazole determination using HPLC with coulometric detection. J Pharm Biomed Anal. 2001; 25: 357-61.
20. Junior IJSde, Sartor JP, Rosa PCP, Veredas Vde, Júnior AGB, Santana CC High-performance liquid chromatographic separation of rolipram, bupivacaine and omeprazole using a tartardiamide-based stationary phase: Influence of flow rate and temperature on the enantioseparation. J. of Chromatogr A 2007; 1162: 97-102.
21. Ribani M, Collins CH, Bottoli CBG Validation of chromatographic methods: Evaluation of detection and quantification limits in the determination of impurities in omeprazole. J of Chromatogr A 2007; 1156: 201-205.
22. Petsalo A, Turpeinen M, Pelkonen O, Tolonen A Analysis of nine drugs and their cytochrome P450-specific probe metabolites from urine by liquid chromatography-tandem mass spectrometry utilizing sub 2 μm particle size column. J of Chromatogr A 2008; 1215: 107-115.
23. Raval PB, Puranik M, Wadher SJ, Yeole PG A validated HPTLC method for determination of ondansetron in combination with omeprazole or rabeprazole in solid dosage form. Indian J of Pharm Sci 2008; 70: 386-390.
24. Panigrahi D, Sharma R Development and validation of an RP-HPLC method for simultaneous analysis of drotaverine and omeprazole in a tablet dosage form. Acta Chromatographica 2008; 20: 439-450.
25. ICH, Q2(R1): Validation Of Analytical Procedures: Text And Methodology, Geneva, 2005.