Blood culture contamination in a district general hospital in the UK: A 1-year study

Healthcare Infection

Volumn 14, Issue 3, 2009, Pages 95-100

  Raja, Nadeem Sajjad ^a   Parratt, David ^a   Meyers, Marilyn ^a  

^a SOUTHEND UNIVERSITY HOSPITAL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EXTENDED SPECTRUM BETA LACTAMASE;

ACINETOBACTER; ADULT; ARTICLE; BACILLUS; BACTERIUM CONTAMINATION; BACTERIUM ISOLATION; BLOOD CULTURE; BLOODSTREAM INFECTION; CANDIDA; CITROBACTER; CLINICAL STUDY; COAGULASE NEGATIVE STAPHYLOCOCCUS; CORYNEBACTERIUM DIPHTHERIAE; ENTEROBACTER; ESCHERICHIA COLI; FALSE POSITIVE RESULT; FUNGUS ISOLATION; GENERAL HOSPITAL; HUMAN; KLEBSIELLA; LISTERIA; MAJOR CLINICAL STUDY; MEDICAL RECORD REVIEW; METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS; MORGANELLA; PREVALENCE; PROPIONIBACTERIUM; PROTEUS; PSEUDOMONAS AERUGINOSA; PUBLIC HOSPITAL; RETROSPECTIVE STUDY; STAPHYLOCOCCUS AUREUS; STREPTOCOCCUS; STREPTOCOCCUS PNEUMONIAE; UNITED KINGDOM;

EID: 77953369986     PISSN: 18355617     EISSN: None     Source Type: Journal    
DOI: 10.1071/HI09012     Document Type: Article

References (33)

1. Leibovici L, Sharga I, Drucker M, Konigsberger H, Samra Z, Pitlik SD. The benefit of appropriate empirical antibiotic treatment in patients with bloodstream infection. J Intern Med 1998; 244: 379-386 doi:10.1046/j.1365-2796. 1998.00379.x (Pubitemid 28513125)
2. Lee CC, Lin WJ, Shih HI, Wu CJ, Chen PL, Lee HC, et al. Clinical significance of potential contaminants in blood cultures among patients in a medical centre. J Microbiol Immunol Infect 2007; 40: 438-444
3. Karunakaran R, Raja NS, Ng KP, Navaratnam P. Etiology of blood culture isolates among patients in a multidisciplinary teaching hospital in Kuala Lumpur. J Microbiol Immunol Infect 2007; 40: 432-437
4. Bryan CS. Clinical implications of positive blood cultures. Clin Microbiol Rev 1989; 2: 329-353 (Pubitemid 19249265)
5. Weinstein MP. Blood culture contamination: persisting problems and partial progress. J Clin Microbiol 2003; 41: 2275-2278 doi:10.1128/JCM.41.6. 2275-2278.2003
6. Bates DW, Goldman L, Lee TH. Contaminated blood cultures and resource utilisation: the true consequences of false positive results. JAMA 1991; 265: 365-369 doi:10.1001/jama.265.3.365
7. Archibald LK, Pallangyo K, Kazembe P, Reller LB. Blood culture contamination in Tanzania, Malawi, and the United States: a microbiological tale of three cities. J Clin Microbiol 2006; 44: 4425-4429 doi:10.1128/JCM.01215-06 (Pubitemid 44937074)
8. Bekeris LG, Tworek JA, Walsh MK, Valenstein PN. Trends in blood culture contamination: a College of American Pathologists Q-Tracks study of 356 institutions. Arch Pathol Lab Med 2005; 129: 1222-1225
9. Calfee DP, Farr BM. Comparison of four antiseptic preparations for skin in the prevention of contamination of percutaneously drawn blood cultures: a randomized trial. J Clin Microbiol 2002; 40: 1660-1665 doi:10.1128/JCM.40.5. 1660-1665.2002
10. Weinbaum FI, Lavie S, Danek M, Sixsmith D, Heinrich GF, Mills SS. Doing it right the first time: quality improvement and the contaminant blood culture. J Clin Microbiol 1997; 35: 563-565 (Pubitemid 27083838)
11. Weinstein MP, Towns ML, Quartey SM, Mirrett S, Reimer LG, Parmigiani G, et al. The clinical significance of positive blood cultures in the 1990s: a prospective comprehensive evaluation of the microbiology, epidemiology, and outcome of bacteremia and fungemia in adults. Clin Infect Dis 1997; 24: 584-602. (Pubitemid 27143552)
12. Qamruddin A, Khanna N, Orr D. Peripheral blood culture contamination in adults and venipuncture technique: prospective cohort study. J Clin Pathol 2008; 61: 509-513 doi:10.1136/jcp.2007.047647
13. Eskira S, Gilad J, Schlaeffer P, Hyam E, Peled N, Karakis I, et al. Reduction of blood culture contamination rate by an educational intervention. Clin Microbiol Infect 2006; 12: 818-821 (Pubitemid 43983814)
14. Hall KK, Lyman JA. Update review of blood culture contamination. Clin Microbiol Rev 2006; 19: 788-802. doi:10.1128/CMR.00062-05
15. Smith JA, Bryce EA, Ngui-yen JH, Roberts FJ. Comparison of BACTEC 9240 and BacT/Alert blood culture systems in an adult hospital. J Clin Microbiol 1995; 33: 1905-1908
16. Bryant JK, Strand CL. Reliability of blood cultures collected from intravascular catheter versus venipuncture. Am J Clin Pathol 1987; 88: 113-116
17. Surdulescu S, Utamsingh D, Shekar R. Phlebotomy teams reduce blood culture contamination rate and save money. Clin Perform Qual Health Care 1998; 6: 60-62
18. Madeo M, Jackson T, Williams C. Simple measures to reduce the rate of contamination of blood cultures in Accident and Emergency. Emerg Med J 2005; 22: 810-811 doi:10.1136/emj.2005.003079 (Pubitemid 41644795)
19. Lyytikäinen O, Lumio J, Sarkinnen H, Kolho E, Kostiala A, Ruutu P. Nosocomial bloodstream infections in Finnish hospitals during 1999-2000. Clin Infect Dis 2002; 35: e14-19. doi:10.1086/340981
20. Karlowsky JA, Jones ME, Draghi DC, Thornsberry C, Sahm DF, Volturo GA. Prevalence and antimicrobial susceptibilities of bacteria isolated from blood cultures of hospitalized patients in the United States in 2002. Ann Clin Microbiol Antimicrob 2004; 3: 7. doi:10.1186/1476-0711-3-7
21. Bansal S, Jain A, Agarwal J, Malik GK. Significance of coagulase negative staphylococci in neonates with late onset septicaemia. Indian J Pathol Microbiol 2004; 47: 586-588
22. Favre B, Hugonnet S, Correa L, Sax H, Rohner P, Pittet D. Nosocomial bacteremia: clinical significance of a single blood culture positive for coagulase-negative staphylococci. Infect Control Hosp Epidemiol 2005; 26: 697-702. doi:10.1086/502605 (Pubitemid 41169739)
23. Beekmann SE, Diekema DJ, Doern GV. Determining the clinical significance of coagulase negative staphylococci isolated from blood cultures. Infect Control Hosp Epidemiol 2005; 26: 559-566 doi:10.1086/502584
24. Bodonaik NC, Moonah S. Coagulase negative staphylococci from blood cultures: contaminants or pathogens? West Indian Med J 2006; 55: 174-182 doi:10.1590/S0043-31442006000300009
25. Herwaldt LA, Geiss M, Kao C, Pfaller MA. The positive predictive value of isolating coagulase-negative staphylococci from blood cultures. Clin Infect Dis 1996; 22: 14-20. (Pubitemid 2618189)
26. Souvenir D, AndersonDEJr, Palpant S, Mroch H, Askin S, Anderson J, et al. Blood cultures positive for coagulase-negative staphylococci: antisepsis, pseudobacteremia, and therapy of patients. J Clin Microbiol 1998; 36: 1923-1926 (Pubitemid 28277777)
27. Mirrett S, Weinstein MP, Reimer LG, Wilson ML, Reller LB. Relevance of the number of positive bottles in determining clinical significance of coagulase-negative staphylococci in blood cultures. J Clin Microbiol 2001; 39: 3279-3281 doi:10.1128/JCM.39.9.3279-3281.2001 (Pubitemid 32830327)
28. Health Protection Agency. Mandatory Staphylococcus aureus bacteraemia surveillance scheme. London: Health Protection Agency; 2009. Available online at: http://www.hpa.org.uk/webw/HPAweb&Page&HPAwebAutoListName/Page/ 1191942169773?p=1191942169773 [verified June 2009].
29. Wisplinghoff H, Bischoff T, Tallent SM, Seifert H, Wenzel RP, Edmond MP. Nosocomial bloodstream infections in US hospitals: analysis of 24 179 cases from a prospective nationwide surveillance study. Clin Infect Dis 2004; 39: 309-317 doi:10.1086/421946 (Pubitemid 39050477)
30. Reynold R, Potz N, Colman M, Williams A, Livermore D, MacGowan A, BSAC Working Party on Bacteraemia Resistance Surveillance. Antimicrobial susceptibility of the pathogens of bacteremia in the UK and Ireland 2001-2002: the BSAC Bacteraemia Resistance Surveillance Programme. J Antimicrob Chemother 2004; 53: 1018-1032 (Pubitemid 38807644)
31. Cox RA, Conquest C, Mallaghan C, Marples RR. A major outbreak of methicillin-resistant Staphylococcus aureus caused by a new phage-type (EMRSA-16). J Hosp Infect 1995; 29: 87-106. doi:10.1016/0195-6701(95)90191-4
32. Johnson AP, Pearson A, Duckworth G. Surveillance and epidemiology ofMRSAbacteraemia in the UK. J Antimicrob Chemother 2005; 56: 455-462
33. Hyle EP, Lipworth AD, Zaotis TE, Nachamkin I, Fishman NO, Bilker WB, et al. Risk factors for increasing multidrug resistance among extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella species. Clin Infect Dis 2005; 40: 1317-1324 doi:10.1086/429239 (Pubitemid 40570242)