Folate antagonist, methotrexate induces neuronal differentiation of human embryonic stem cells transplanted into nude mouse retina

Neuroscience Letters

Volumn 477, Issue 3, 2010, Pages 138-143

  Hara, Akira ^a   Taguchi, Ayako ^a   Aoki, Hitomi ^a   Hatano, Yuichiro ^a   Niwa, Masayuki ^b   Yamada, Yasuhiro ^a   Kunisada, Takahiro ^a  

^a GIFU UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b GIFU UNIVERSITY   (Japan)

Author keywords

Human ES cell; Methotrexate; Mouse; Neuronal differentiation; Retina; Transplantation

Indexed keywords

KI 67 ANTIGEN; METHOTREXATE; N METHYL DEXTRO ASPARTIC ACID; OCTAMER TRANSCRIPTION FACTOR 4;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CARCINOGENICITY; CELL PROLIFERATION; CELL STRUCTURE; CELL SURVIVAL; CONTROLLED STUDY; DRUG ADMINISTRATION ROUTE; EMBRYONIC STEM CELL; FEMALE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; MITOSIS INDEX; MOUSE; NERVE CELL DIFFERENTIATION; NONHUMAN; NUDE MOUSE; PRIORITY JOURNAL; RETINA GANGLION CELL; RETINA INJURY; STEM CELL TRANSPLANTATION;

ANIMALS; CELL DIFFERENTIATION; DEPRESSION, CHEMICAL; EMBRYONIC STEM CELLS; FOLIC ACID ANTAGONISTS; HUMANS; KI-67 ANTIGEN; METHOTREXATE; MICE; MICE, NUDE; MITOSIS; NEUROGLIA; NEURONS; OCTAMER TRANSCRIPTION FACTOR-3; RETINA; STEM CELL TRANSPLANTATION; TERATOMA;

EID: 77953361020     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.04.050     Document Type: Article

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