A comparison of diabetes medication adherence and healthcare costs in patients using mail order pharmacy and retail pharmacy

Journal of Medical Economics

Volumn 13, Issue 2, 2010, Pages 203-211

  Devine, Scott ^a   Vlahiotis, Anna ^a   Sundar, Heather ^a  

^a Express Scripts   (United States)

Author keywords

Adherence; Healthcare costs; Mail order pharmacy

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ALPHA GLUCOSIDASE INHIBITOR; AMINO ACID DERIVATIVE; AMYLIN DERIVATIVE; BIGUANIDE DERIVATIVE; INCRETIN MIMETIC AGENT; MEGLITINIDE DERIVATIVE; ORAL ANTIDIABETIC AGENT; SULFONYLUREA DERIVATIVE; UNCLASSIFIED DRUG;

ADULT; ARTICLE; COHORT ANALYSIS; COMPARATIVE STUDY; CONTROLLED STUDY; COST OF ILLNESS; DATA BASE; DIABETES MELLITUS; DISEASE DURATION; DRUG COST; FEMALE; FOLLOW UP; HEALTH CARE COST; HUMAN; MAJOR CLINICAL STUDY; MALE; PATIENT COMPLIANCE; PHARMACY; POSTAL MAIL; PRESCRIPTION; PROBABILITY; PROPENSITY SCORE; RETROSPECTIVE STUDY; SCORING SYSTEM;

ADOLESCENT; ADULT; COMMUNITY PHARMACY SERVICES; DIABETES COMPLICATIONS; DIABETES MELLITUS, TYPE 2; HEALTH EXPENDITURES; HUMANS; HYPOGLYCEMIC AGENTS; INSURANCE CLAIM REVIEW; MEDICATION ADHERENCE; MIDDLE AGED; PHARMACEUTICAL SERVICES; POSTAL SERVICE; RETROSPECTIVE STUDIES; YOUNG ADULT;

EID: 77953353694     PISSN: 13696998     EISSN: None     Source Type: Journal    
DOI: 10.3111/13696991003741801     Document Type: Article

References (28)

1. Balkrishnan R, Rajagopalan R, Camacho FT, et al. Predictors of medication adherence and associated health care costs in an older population with type 2 diabetes mellitus: a longitudinal cohort study. Clin Ther 2003;25:2958-2971.
2. Hoerger TJ. Using costs in cost-effectiveness models for chronic diseases: lessons from diabetes. Med Care 2009;47:S21-27.
3. Hunt J, Rozenfeld Y, Shenolikar R. Effect of patient medication cost share on adherence and glycemic control. Manag Care 2009;18:47-53.
4. Ly D, Alex FZ, Christopher H. Cost effectiveness analysis of a hypertension management program in patients with type 2 diabetes. J Clin Hypertens (Greenwich) 2009;11:116-124.
5. Goldfarb N, Weston C, Hartmann CW, et al. Impact of appropriate pharmaceutical therapy for chronic conditions on direct medical costs and workplace productivity: a review of the literature. Dis Manag 2004;7:61-75.
6. Goldman DP, Joyce GF, Zheng Y. Prescription drug cost sharing: associations with medication and medical utilization and spending and health. JAMA 2007;298:61-69.
7. Harrold LR, Andrade SE. Medication adherence of patients with selected rheumatic conditions: a systematic review of the literature. Semin Arthritis Rheum 2009;38:396-402.
8. Sokol MC, McGuigan KA, Verbrugge RR, et al. Impact of medication adherence on hospitalization risk and healthcare cost. Med Care 2005;43:521-530.
9. McDonald HP, Garg AX, Haynes RB. Interventions to enhance patient adherence to medication prescriptions: scientific review. JAMA 2002;288:2868-2879.
10. Chapman RH, Benner JS, Petrilla AA, et al. Predictors of adherence with antihypertensive and lipid-lowering therapy. Arch Intern Med 2005;165:1147-1152.
11. Benner JS, Glynn RJ, Mogun H, et al. Long-term persistence in use of statin therapy in elderly patients. JAMA 2002;288:455-461.
12. Gross R, Zhang Y, Grossberg R. Medication refill logistics and refill adherence in HIV. Pharmacoepidemiol Drug Saf 2005;14:789-793.
13. Duru OK, Schmittdiel JA, Dyer WT, et al. Mail-order pharmacy use and adherence to diabetes-related medications. Am J Manag Care 2010;16:33-40.
14. Turner RC, Cull CA, Frighi V, et al. Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group. JAMA 1999;281: 2005-2012.
15. Kosanke J, Bergstralh EJ. gmatch SAS Macro. [SAS Macro] 2003 4/7/ 2004 [cited 2009 June 29]; Match 1 or more controls to cases using the GREEDY algorithm]. Available from: http://mayoresearch.mayo. edu/mayo/research/biostat/ upload/gmatch.sas
16. Perkins SM, Tu W, Underhill MG, et al. The use of propensity scores in pharmacoepidemiologic research. Pharmacoepidemiol Drug Saf 2000;9:93-101.
17. D'Agostino RB, Jr. Propensity score methods for bias reduction in the comparison of a treatment to a non-randomized control group. Stat Med 1998;17:2265-2281.
18. Rosenbaum PR, Rubin DB. Reducing bias in observational studies using subclassification on the propensity score. J AmStat Assoc 1984; 79:516-524.
19. Barron J, Wahl P, Fisher M, et al. Effect of prescription copayments on adherence and treatment failure with oral antidiabetic medications. P T 2008;33:532-553.
20. Osterberg L, Blaschke T. Adherence to medication. N Engl J Med 2005;353:487-497.
21. Charlson M, Szatrowski TP, Peterson J, et al. Validation of a combined comorbidity index. J Clin Epidemiol 1994;47:1245-1251.
22. Young BA, Lin E, Von Korff M, et al. Diabetes complications severity index and risk of mortality, hospitalization, and healthcare utilization. Am J Manag Care 2008;14:15-23.
23. Maddala GS. Limited-Dependent and Qualitative Variables in Econometrics. New York, NY: Cambridge University Press, 1983.
24. OoHP. Basic HHS Policy for Protection of Human Research Subjects. In: Service HaH, ed. 2009.
25. Adherence to Chronic Medications. NCQ# 0542: The National Quality Forum 2009.
26. Pladevall M, Williams LK, Potts LA, et al. Clinical outcomes and adherence to medications measured by claims data in patients with diabetes. Diabetes Care 2004;27:2800-2805.
27. Nathan DM. Long-term complications of diabetes mellitus. N Engl J Med 1993;328:1676-1685.
28. Brandle M, Zhou H, Smith BR, et al. The direct medical cost of type 2 diabetes. Diabetes Care 2003;26:2300-2304.