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Volumn 139, Issue 1-3, 2010, Pages 348-352

Microdosing for early biokinetic studies in humans

Author keywords

[No Author keywords available]

Indexed keywords

DRUG;

EID: 77953353160     PISSN: 01448420     EISSN: None     Source Type: Journal    
DOI: 10.1093/rpd/ncq029     Document Type: Article
Times cited : (5)

References (15)
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    • DiMasi, A. Risks in new drug development: approval, success rates for investigational drugs. Clin. Pharm. Ther. 69, 297-307 (2001).
    • (2001) Clin. Pharm. Ther. , vol.69 , pp. 297-307
    • DiMasi, A.1
  • 2
    • 0037365932 scopus 로고    scopus 로고
    • Big physics, small doses - the use of AMS and PET in human microdosing of development drugs
    • Lappin, G. and Garner, R. C. Big physics, small doses - the use of AMS and PET in human microdosing of development drugs. Nat. Rev. Drug Discov. 2, 233-240 (2003).
    • (2003) Nat. Rev. Drug Discov. , vol.2 , pp. 233-240
    • Lappin, G.1    Garner, R.C.2
  • 3
    • 33645036518 scopus 로고    scopus 로고
    • The phase 0 microdosing concept
    • Garner, R. C. and Lappin, G. The phase 0 microdosing concept. Br. J. Clin. Pharmacol. 61(4), 367-370 (2006).
    • (2006) Br. J. Clin. Pharmacol. , vol.61 , Issue.4 , pp. 367-370
    • Garner, R.C.1    Lappin, G.2
  • 5
    • 77953352970 scopus 로고    scopus 로고
    • Guidance for industry, investigators and reviewers: exploratory IND studies
    • Center for Drug Evaluation and Research. (US Dep. of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research)
    • Center for Drug Evaluation and Research. Guidance for industry, investigators and reviewers: exploratory IND studies. Draft guidance (US Dep. of Health and Human Services, Food and Drug Administration, Center for Drug Evaluation and Research) (2004).
    • (2004) Draft guidance
  • 6
    • 0037406978 scopus 로고    scopus 로고
    • Early microdose drug studies in human volunteers can minimise animal testing: proceedings of a workshop organised by Volunteers in Research and Testing
    • Combes, R. D., Berridge, T., Connelly, J., Eve, M. D., Garner, R. C., Toon, S. and Wilcox, P. Early microdose drug studies in human volunteers can minimise animal testing: proceedings of a workshop organised by Volunteers in Research and Testing. Eur. J. Pharm. Sci. 19, 1-11 (2003).
    • (2003) Eur. J. Pharm. Sci. , vol.19 , pp. 1-11
    • Combes, R.D.1    Berridge, T.2    Connelly, J.3    Eve, M.D.4    Garner, R.C.5    Toon, S.6    Wilcox, P.7
  • 7
    • 58149188094 scopus 로고    scopus 로고
    • The utility of microdosing over the past 5 years
    • Lappin, G. and Garner, R. C. The utility of microdosing over the past 5 years. Expert Opin. Drug Metab. Toxicol. 4(12), 1499-1506 (2008).
    • (2008) Expert Opin. Drug Metab. Toxicol. , vol.4 , Issue.12 , pp. 1499-1506
    • Lappin, G.1    Garner, R.C.2
  • 8
    • 77953330205 scopus 로고    scopus 로고
    • EUMAPP document. Outcomes from EUMAPP - a study comparing and pharmacological pharmacokinetics
    • EUMAPP document. Outcomes from EUMAPP - a study comparing and pharmacological pharmacokinetics. www.eumapp.com (2009).
  • 9
    • 0001229045 scopus 로고    scopus 로고
    • Accelerator mass spectrometry and its applications
    • Fifield, L. K. Accelerator mass spectrometry and its applications. Rep. Phys. Prog. 62, 1223-1274 (1999).
    • (1999) Rep. Phys. Prog. , vol.62 , pp. 1223-1274
    • Fifield, L.K.1
  • 10
    • 34248359096 scopus 로고    scopus 로고
    • The single stage AMS machine at Lund University: Status Report
    • Skog, G. The single stage AMS machine at Lund University: Status Report. Nucl. Instr. Meth. B259, 1-6 (2007).
    • (2007) Nucl. Instr. Meth. , vol.B259 , pp. 1-6
    • Skog, G.1
  • 12
    • 77949891861 scopus 로고    scopus 로고
    • 14C sample preparation for AMS microdosing studies at Lund University with on-line combustion and septa-sealed vials
    • doi:10. 1016/j. nimb. 2009. 10. 065
    • 14C sample preparation for AMS microdosing studies at Lund University with on-line combustion and septa-sealed vials. Nucl. Instr. Meth. B. doi:10.1016/j.nimb.2009.10.065 (2009).
    • (2009) Nucl. Instr. Meth. B
    • Sydoff, M.1    Stenström, K.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.