Advanced paternal age, mortality, and suicide in the general population

Journal of Nervous and Mental Disease

Volumn 198, Issue 6, 2010, Pages 404-411

  Miller, Brian ^a,b   Alaräisänen, Antti ^b   Miettunen, Jouko ^b   Järvelin, Marjo Riitta ^b,c   Koponen, Hannu ^b,d   Räsänen, Pirkko ^b   Isohanni, Matti ^b   Kirkpatrick, Brian ^a  

^a MEDICAL COLLEGE OF GEORGIA   (United States)

^b UNIVERSITY OF OULU   (Finland)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d UNIVERSITY OF EASTERN FINLAND   (Finland)

Author keywords

Epidemiology; Gender; Mortality; Paternal age; Suicide

Indexed keywords

ADULT; ARTICLE; ATTRIBUTABLE RISK; COHORT ANALYSIS; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; FINLAND; GENDER; HAZARD RATIO; HUMAN; MAJOR CLINICAL STUDY; MALE; MATERNAL AGE; MORTALITY; PARITY; PATERNAL AGE; PROGENY; RISK FACTOR; SOCIAL CLASS; SUICIDE;

ADULT; AGE DISTRIBUTION; CAUSE OF DEATH; COHORT STUDIES; FEMALE; FINLAND; HUMANS; LONGITUDINAL STUDIES; MALE; MATERNAL AGE; MIDDLE AGED; PARENTS; PATERNAL AGE; PROPORTIONAL HAZARDS MODELS; RISK FACTORS; SEX FACTORS; SOCIAL CLASS; SUICIDE;

EID: 77953348695     PISSN: 00223018     EISSN: None     Source Type: Journal    
DOI: 10.1097/NMD.0b013e3181e07d79     Document Type: Article

References (43)

1. Adam KS, Boukoms A, Streiner D (1982) Parental loss and family stability in attempted suicide. Arch Gen Psychiatry. 39:1081-1085.
2. Alaraisanen A, Miettunen J, Lauronen E, Rasanen P, Isohanni M (2006) Good school performance is a risk factor of suicide in psychoses: A 35-year follow up of the Northern Finland 1966 Birth Cohort. Acta Psychiatr Scand. 114:357-362.
3. Barker DJ, Hales CN, Fall CH, Osmond C, Phipps K, Clark PM (1993) Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): Relation to reduced fetal growth. Diabetologia. 36:62-67.
4. Bertram L, Busch R, Spiegl M, Lautenschlager NT, Müller U, Kurz A (1998) Paternal age is a risk factor for Alzheimer disease in the absence of a major gene. Neurogenetics. 1:277-280.
5. Bray I, Gunnell D, Davey Smith G (2006) Advanced paternal age: How old is too old? J Epidemiol Community Health. 60:851-853.
6. Brezo J, Klempan T, Turecki G (2008) The genetics of suicide: A critical review of molecular studies. Pscyhiatr Clin North Am. 31:179-203.
7. Brown AS, van Os J, Driessens C, Hoek HW, Susser ES (2000a) Further evidence of relation between prenatal famine and major affective disorder. Am J Psychiatry. 157:190-195.
8. Brown AS, Schaefer CA, Wyatt RJ, Goetz R, Begg MD, Gorman JM, Susser ES (2000b) Maternal exposure to respiratory infections and adult schizophrenia spectrum disorders: A prospective birth cohort study. Schizophr Bull. 26:287-295.
9. Crow JF (1997) The high spontaneous mutation rate: Is it a health risk? Proc Natl Acad Sci U S A. 94:8380-8386.
10. Dube SR, Anda FR, Felitti VJ, Chapman DP, Williamson DF, Giles WH (2001) Childhood abuse, household dysfunction and the risk of attempted suicide throughout the life span: Findings from the Adverse Childhood Experiences Study. JAMA. 286:3089-3096.
11. Ekéus C, Olausson PO, Hjern A (2006) Psychiatric morbidity is related to parental age: A national cohort study. Psychol Med. 36:269-276.
12. Farrer LA, Cupples LA, Kiely DK, Conneally PM, Myers RH (1992) Inverse relationship between age at onset of Huntington disease and paternal age suggests involvement of genetic imprinting. Am J Hum Genet. 50:528-535.
13. Frans EM, Sandin S, Reichenberg A, Lichtenstein P, Langstrom N, Hultman CM (2008) Advancing paternal age and bipolar disorder. Arch Gen Psychiatry. 65:1034-1040.
14. Gavrilov LA, Garvrilova NS (2000) Human longevity and parental age at conception. In JM Robine (Ed), Sex and Longevity: Sexuality, Gender, Reproduction, Parenthood. Berlin, Heidelberg: Springer-Verlag.
15. Glowinski AL, Jacob T, Bucholz KK, Scherrer FJ, True W, Heath AC (2004) Paternal alcohol dependence and offspring suicidal behaviors in a children-oftwins study. Drug Alcohol Depend. 76:S69-S77.
16. Gourbin C (2005) Foetal mortality, infant mortality and age of parents. An overview. Rev Epidemiol Sante Publique. 53:S81-S86.
17. Greenland S, Robins JM (1988) Conceptual problems in the definition and interpretation of attributable fraction. Am J Epidemiol. 128:1185-1197.
18. Hakko H, Rasanen P, Jarvelin MR, Tiihonen J (1998) Parental age gap and child sex ratio-Fact or fiction? Int J Epidemiol. 27:929-930.
19. Hales CN, Barker DJ (2001) The thrifty phenotype hypothesis. Br Med Bull. 60:5-20.
20. Harjutsalo V, Podar T, Tuomilehto J (2005) Cumulative incidence of type 1 diabetes in 10,168 siblings of Finnish young-onset type 1 diabetic patients. Diabetes. 54:563-569.
21. Inset BJ, Brown AS, Bresnahan MA, Schaefer CA, Susser ES (2005) Maternalfetal blood incompatibility and the risk of schizophrenia in offspring. Schizophr Res. 80:331-342.
22. Kaijse M, Akre O, Cnattingius S, Ekbom A (2003) Maternal lung cancer and testicular cancer risk in the offspring. Cancer Epidemiol Biomarkers Prev. 12:643-646. (Pubitemid 36899845)
23. Kinzler WL, Ananth CV, Smulian JC, Vintzileos AM (2002) Parental age difference and adverse perinatal outcomes in the United States. Paediatr Perinat Epidemiol. 16:320 327.
24. Lahti RA, Penttila A (2001) The validity of death certificates: Routine validation of death certification and its effects on mortality statistics. Forensic Sci Int. 115:15-32.
25. Laursen TM, Munk-Olsen T, Nordentoft M, Bo Mortensen P (2007) A comparison of selected risk factors for unipolar depressive disorder, bipolar affective disorder, schizoaffective disorder and schizophrenia from a Danish populationbased cohort. J Clin Psychiatry. 68:1673-1681.
26. Lester D (1989) Experience of parental loss and later suicide: Data from published biographies. Acta Psychiatr Scand. 79:450-452.
27. Manning JT, Anderson RH, Shutt M (1997) Parental age gap skews child sex ratio. Nature. 389:344.
28. Mittendorfer-Rutz E, Rasmussen F, Wasserman D (2004) Restricted fetal growth and adverse maternal psychosocial and socioeconomic conditions as risk factors for suicidal behaviour of offspring: A cohort study. Lancet. 364:1135-1140.
29. Myhrman A (1988) Family relation and social competence of children unwanted at birth. A follow-up study at the age of 16. Acta Psychiatr Scand. 77:181-187.
30. Osmond C, Barker DJ (2000) Fetal, infant, and childhood growth are predictors of coronary heart disease, diabetes and hypertension in adult men and women. Environ Health Perspect. 108:545-553.
31. Ozanne SE, Hales CN (2002) Early programming of glucose-insulin metabolism. Trends Endocrinol Metab. 13:368-373.
32. Perrin MC, Brown AS, Malaspina D (2007) Aberrant epigenetic regulation could explain the relationship of paternal age to schizophrenia. Schizophr Bull. 33:1270-1273.
33. Rantakallio P (1969) Groups at risk in low birth weight infants and perinatal mortality. Acta Paediatr Scand. 193:1-71.
34. Reichenberg A, Gross R, Weiser M, Bresnahan M, Silverman J, Harlap S, Rabinowitz J, Shulman C, Malaspina D, Lubin G, Knobler HY, Davidson M, Susser E (2006) Advancing paternal age and autism. Arch Gen Psychiatry. 63:1026-1032.
35. Riordan DV, Selvaraj S, Stark C, Gilbert JS (2006). Perinatal circumstances and risk of offspring suicide. Birth cohort study. Br J Psychiatry. 189:502-507.
36. Robine JM, Allard M (1997) Towards a genealogical epidemiology of longevity. In JM Robine, JW Vaupel, B Jeune, M Allard (Eds), Longevity: To the Limits and Beyond. Berlin, Heidelberg: Springer-Verlag.
37. Susser E, Neugebauer R, Hoek HW, Brown AS, Lin S, Labovitz D, Gorman JM (1996) Schizophrenia after prenatal famine. Further evidence. Arch Gen Psychiatry. 53:25-31.
38. Vestergaard M, Mork A, Madsen KM, Olsen J (2005) Paternal age and epilepsy in the offspring. Eur J Epidemiol. 20:1003-1005.
39. Webb RT, Pickles AR, Appleby L, Mortensen PB, Abel KM (2007) Death by unnatural causes during childhood and early adulthood in offspring of psychiatric inpatients. Arch Gen Psychiatry. 64:345-352.
40. Wohl M, Gorwood P (2007) Paternal ages below or above 35 years old are associated with a different risk of schizophrenia in the offspring. Eur Psychiatry. 22:22-26.
41. Zhang Y, Kreger BE, Dorgan JF, Cupples LA, Myers RH, Splansky GL, Schatzkin A, Ellison RC (1999) Parental age at child's birth and son's risk of prostate cancer. The Framingham Study. Am J Epidemiol. 150:1208-1212.
42. Zhu JL, Madsen KM, Vestergaard M, Basso O, Olsen J (2005) Paternal age and preterm birth. Epidemiology. 16:259-262.
43. Zhu JL, Vestergaard M, Madsen KM, Olson J (2008) Paternal age and mortality in children. Eur J Epidemiol. 23:443-447.