The role of serum cryptococcal antigen screening for the early diagnosis of cryptococcosis in HIV-infected patients with different ranges of CD4 cell counts

Journal of Infection

Volumn 60, Issue 6, 2010, Pages 474-477

  Pongsai, Pannee ^a   Atamasirikul, Kalayanee ^a   Sungkanuparph, Somnuek ^a  

^a MAHIDOL UNIVERSITY   (Thailand)

Author keywords

AIDS; Cryptococcosis; HIV; Screening; Serum cryptococcal antigen

Indexed keywords

AMPHOTERICIN B; ANTIRETROVIRUS AGENT; CD4 ANTIGEN; FLUCONAZOLE; FUNGUS ANTIGEN;

ADULT; ANTIGEN DETECTION; ARTICLE; CD4 LYMPHOCYTE COUNT; CEREBROSPINAL FLUID ANALYSIS; COHORT ANALYSIS; COMORBIDITY; CONTROLLED STUDY; CRYPTOCOCCAL MENINGITIS; CRYPTOCOCCOSIS; CRYPTOCOCCUS; EARLY DIAGNOSIS; FEMALE; FOLLOW UP; FUNGUS CULTURE; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; INCIDENCE; LATEX AGGLUTINATION TEST; LUMBAR PUNCTURE; MAJOR CLINICAL STUDY; MALE; PREVALENCE; RISK FACTOR; TERTIARY HEALTH CARE; THORAX RADIOGRAPHY;

ADULT; AIDS-RELATED OPPORTUNISTIC INFECTIONS; ANTIGENS, FUNGAL; CD4 LYMPHOCYTE COUNT; CD4-POSITIVE T-LYMPHOCYTES; COHORT STUDIES; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; FEMALE; HIV-1; HUMANS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; RETROSPECTIVE STUDIES; STATISTICS, NONPARAMETRIC;

EID: 77953325710     PISSN: 01634453     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jinf.2010.03.015     Document Type: Article

References (14)

1. Chariyalertsak S., Sirisanthana T., Saengwonloey O., Nelson K.E. Clinical presentation and risk behaviors of patients with acquired immunodeficiency syndrome in Thailand, 1994-1998: regional variation and temporal trends. Clin Infect Dis 2001, 32:955-962.
2. French N., Gray K., Watera C., Nakiyingi J., Lugada E., Moore M., et al. Cryptococcal infection in a cohort of HIV-1-infected Ugandan adults. AIDS 2002, 16:1031-1038.
3. Corbett E.L., Churchyard G.J., Charalambos S., Samb B., Moloi V., Clayton T.C., et al. Morbidity and mortality in South African gold miners: impact of untreated disease due to human immunodeficiency virus. Clin Infect Dis 2002, 34:1251-1258.
4. Jongwutiwes U., Kiertiburanakul S., Sungkanuparph S. Impact of antiretroviral therapy on the relapse of cryptococcosis and survival of HIV-infected patients with cryptococcal infection. Curr HIV Res 2007, 5:355-360.
5. Micol R., Lortholary O., Sar B., Laureillard D., Ngeth C., Dousset J.P., et al. Prevalence, determinants of positivity, and clinical utility of cryptococcal antigenemia in Cambodian HIV-infected patients. J Acquir Immune Defic Syndr 2007, 45:555-559.
6. Bicanic T., Meintjes G., Wood R., Hayes M., Rebe K., Bekker L.G., et al. Fungal burden, early fungicidal activity, and outcome in cryptococcal meningitis in antiretroviral-naïve or antiretroviral-experienced patients treated with amphotericin B or fluconazole. Clin Infect Dis 2007, 45:76-80.
7. Kambugu A., Meya D.B., Rhein J., O'Brien M., Janoff E.N., Ronald A.R., et al. Outcomes of cryptococcal meningitis in Uganda before and after the availability of highly active antiretroviral therapy. Clin Infect Dis 2008, 46:1694-1701.
8. Manosuthi W., Chottanapund S., Sungkanuparph S. Mortality rate of early versus deferred initiation of antiretroviral therapy in HIV-1-infected patients with cryptococcal meningitis. J Acquir Immune Defic Syndr 2008, 48:508-509.
9. Temstet A., Roux P., Poirot J.L., Ronin O., Dromer F. Evaluation of a monoclonal antibody-based latex agglutination test for the diagnosis of cryptococcosis: comparison with two tests using polyclonal antibodies. J Clin Microbiol 1992, 30:2544-2550.
10. Lara-Peredo O., Cuevas L.E., French N., Bailey J.W., Smith D.H. Cryptococcal infection in an HIV-positive Ugandan population. J Infect 2000, 41:195.
11. Jarvis J.N., Lawn S.D., Vogt M., Bangani N., Wood R., Harrison T.S. Screening for cryptococcal antigenemia in patients accessing an antiretroviral treatment program in South Africa. Clin Infect Dis 2009, 48:856-862.
12. Sungkanuparph S., Anekthananon T., Hiransuthikul N., Bowonwatanuwong C., Supparatpinyo K., Mootsikapun P., et al. Guidelines for antiretroviral therapy in HIV-1 infected adults and adolescents: the recommendations of the Thai AIDS Society (TAS) 2008. J Med Assoc Thai 2008, 91:1925-1935.
13. Chetchotisakd P., Sungkanuparph S., Thinkhamrop B., Mootsikapun P., Boonyaprawit P. A multicentre, randomized, double-blind, placebo-controlled trial of primary cryptococcal meningitis prophylaxis in HIV-infected patients with severe immune deficiency. HIV Med 2004, 5:140-143.
14. Lortholary O., Fontanet A., Memain N., Martin A., Sitbon K., Dromer F. Incidence and risk factors of immune reconstitution inflammatory syndrome complicating HIV-associated cryptococcosis in France. AIDS 2005, 19:1043-1049. French Cryptococcosis Study Group.