Molecular dynamics simulations of hydrotropic solubilization and self-aggregation of nicotinamide

Journal of Pharmaceutical Sciences

Volumn 99, Issue 7, 2010, Pages 3048-3059

  Cui, Yong ^a   Xing, Chenyue ^b   Ran, Yingqing ^a  

^a GENENTECH INC   (United States)

^b University of California   (United States)

Author keywords

Aggregation; Hydrotropy; Molecular dynamics simulation; Solubilization

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; NICOTINAMIDE; PG 300995; UNCLASSIFIED DRUG; WATER;

AQUEOUS SOLUTION; ARTICLE; BINDING KINETICS; CHEMICAL BINDING; CHEMICAL STRUCTURE; CONTROLLED STUDY; ENERGY; HYDROTROPHIC SOLUBILIZATION; LIQUID; MOLECULAR DYNAMICS; MOLECULAR INTERACTION; MOLECULAR MODEL; PRESSURE; SOLUBILIZATION; SOLUTE; TEMPERATURE DEPENDENCE;

EID: 77953303865     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.22077     Document Type: Article

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