Negative pressure wound therapy for post-sternotomy mediastinitis reduces mortality rate and sternal re-infection rate compared to conventional treatment

European Journal of Cardio-thoracic Surgery

Volumn 38, Issue 1, 2010, Pages 110-113

  Petzina, Rainer ^a   Hoffmann, Julia ^a   Navasardyan, Artashes ^a   Malmsjö, Malin ^b   Stamm, Christof ^a   Unbehaun, Axel ^a   Hetzer, Roland ^a  

^a DEUTSCHES HERZZENTRUM BERLIN   (Germany)

^b LUND UNIVERSITY HOSPITAL   (Sweden)

Author keywords

Cardiac surgery; Mediastinal infection; Wound healing

Indexed keywords

ARTICLE; CONTROLLED STUDY; CORONARY ARTERY BYPASS GRAFT; HEART SURGERY; HUMAN; LENGTH OF STAY; MAJOR CLINICAL STUDY; MEDIASTINITIS; OUTCOME ASSESSMENT; POSTOPERATIVE COMPLICATION; PRIORITY JOURNAL; REINFECTION; RETROSPECTIVE STUDY; STERNOTOMY; SURGICAL MORTALITY; VACUUM ASSISTED CLOSURE; WOUND HEALING; WOUND INFECTION;

CARDIAC SURGICAL PROCEDURES; HUMANS; LENGTH OF STAY; MEDIASTINITIS; NEGATIVE-PRESSURE WOUND THERAPY; POSTOPERATIVE CARE; RECURRENCE; RETROSPECTIVE STUDIES; STERNUM; SURGICAL WOUND INFECTION; TREATMENT OUTCOME; WOUND HEALING;

EID: 77953287872     PISSN: 10107940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejcts.2010.01.028     Document Type: Article

References (18)

1. Stahle E., Tammelin A., Bergstrom R., Hambreus A., Nystrom S.O., and Hansson H.E. Sternal wound complications-incidence, microbiology and risk factors. Eur J Cardiothorac Surg 11 6 (1997) 1146-1153
2. Lu J.C., Grayson A.D., Jha P., Srinivasan A.K., and Fabri B.M. Risk factors for sternal wound infection and mid-term survival following coronary artery bypass surgery. Eur J Cardiothorac Surg 23 6 (2003) 943-949
3. Argenta L.C., and Morykwas M.J. Vacuum-assisted closure: a new method for wound control and treatment: clinical experience. Ann Plast Surg 38 6 (1997) 563-576 [Discussion 77]
4. Fleischmann W., Lang E., and Kinzl L. Vacuum assisted wound closure after dermatofasciotomy of the lower extremity. Unfallchirurg 99 4 (1996) 283-287
5. Morykwas M.J., Argenta L.C., Shelton-Brown E.I., and McGuirt W. Vacuum-assisted closure: a new method for wound control and treatment: animal studies and basic foundation. Ann Plast Surg 38 6 (1997) 553-562
6. Petzina R., Gustafsson L., Mokhtari A., Ingemansson R., and Malmsjo M. Effect of vacuum-assisted closure on blood flow in the peristernal thoracic wall after internal mammary artery harvesting. Eur J Cardiothorac Surg 30 1 (2006) 85-89
7. Mokhtari A., Petzina R., Gustafsson L., Sjogren J., Malmsjo M., and Ingemansson R. Sternal stability at different negative pressures during vacuum-assisted closure therapy. Ann Thorac Surg 82 3 (2006) 1063-1067
8. Ridderstolpe L., Gill H., Granfeldt H., Ahlfeldt H., and Rutberg H. Superficial and deep sternal wound complications: incidence, risk factors and mortality. Eur J Cardiothorac Surg 20 6 (2001) 1168-1175
9. Lee Jr. A.B., Schimert G., Shaktin S., and Seigel J.H. Total excision of the sternum and thoracic pedicle transposition of the greater omentum; useful stratagems in managing severe mediastinal infection following open heart surgery. Surgery 80 4 (1976) 433-436
10. Jurkiewicz M.J., Bostwick III J., Hester T.R., Bishop J.B., and Craver J. Infected median sternotomy wound. Successful treatment by muscle flaps. Ann Surg 191 6 (1980) 738-744
11. Shumacker Jr. H.B., and Mandelbaum I. Continuous antibiotic irrigation in the treatment of infection. Arch Surg 86 (1963) 384-387
12. Cowan K.N., Teague L., Sue S.C., and Mahoney J.L. Vacuum-assisted wound closure of deep sternal infections in high-risk patients after cardiac surgery. Ann Thorac Surg 80 6 (2005) 2205-2212
13. Kadohama T., Akasaka N., Nagamine A., Nakanishi K., Kiyokawa K., Goh K., and Sasajima T. Vacuum-assisted closure for pediatric post-sternotomy mediastinitis: are low negative pressures sufficient?. Ann Thorac Surg 85 3 (2008) 1094-1096
14. Fleck T.M., Fleck M., Moidl R., Czerny M., Koller R., Giovanoli P., Hiesmayer M.J., Zimpfer D., Wolner E., and Grabenwoger M. The vacuum-assisted closure system for the treatment of deep sternal wound infections after cardiac surgery. Ann Thorac Surg 74 5 (2002) 1596-1600 [Discussion 600]
15. Sjogren J., Nilsson J., Gustafsson R., Malmsjo M., and Ingemansson R. The impact of vacuum-assisted closure on long-term survival after post-sternotomy mediastinitis. Ann Thorac Surg 80 4 (2005) 1270-1275
16. Mokhtari A., Sjogren J., Nilsson J., Gustafsson R., Malmsjo M., and Ingemansson R. The cost of vacuum-assisted closure therapy in treatment of deep sternal wound infection. Scand Cardiovasc J 42 1 (2008) 85-89
17. Doss M., Martens S., Wood J.P., Wolff J.D., Baier C., and Moritz A. Vacuum-assisted suction drainage versus conventional treatment in the management of poststernotomy osteomyelitis. Eur J Cardiothorac Surg 22 6 (2002) 934-938
18. Wild T., Wetzel-Roth W., and Zoch G. Consensus of the German and Austrian Societies for Wound Healing and Wound Management on vacuum closure and the V.A.C. treatment unit. Zentralbl Chir 129 Suppl 1 (2004) S7-S11