Hypoalgesia associated with elevated resting blood pressure: Evidence for endogenous opioid involvement

Journal of Behavioral Medicine

Volumn 33, Issue 2, 2010, Pages 168-176

  Bruehl, Stephen ^a,c   Burns, John W ^b   Chung, Ok Y ^a   Magid, Edward ^b   Chont, Melissa ^a   Gilliam, Wesley ^b   Matsuura, Justin ^b   Somar, Kristin ^b   Goodlad, James K ^a   Stone, Kevin ^a   Cairl, Heather ^a  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b ROSALIND FRANKLIN UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^c VANDERBILT UNIVERSITY MEDICAL CENTER   (United States)

Author keywords

Acute pain; Blood pressure; Emotional arousal; Endogenous opioid; Gender; Opioid blockade

Indexed keywords

NALTREXONE; NARCOTIC ANTAGONIST; OPIATE PEPTIDE;

ADULT; ANGER; ARTICLE; ATTENTION; BLOOD PRESSURE; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DRUG EFFECT; FEMALE; HUMAN; HYPERTENSION; ISCHEMIA; MALE; MAZE TEST; METABOLISM; PAIN; PAIN THRESHOLD; PHYSIOLOGY; PSYCHOLOGICAL ASPECT; RANDOMIZED CONTROLLED TRIAL; REFERENCE VALUE; SEX DIFFERENCE; STATISTICAL MODEL;

ADULT; ANGER; ATTENTION; BLOOD PRESSURE; FEMALE; HUMANS; HYPERTENSION; ISCHEMIA; LINEAR MODELS; MALE; MAZE LEARNING; NALTREXONE; NARCOTIC ANTAGONISTS; OPIOID PEPTIDES; PAIN; PAIN THRESHOLD; REFERENCE VALUES; SEX FACTORS;

EID: 77953287122     PISSN: 01607715     EISSN: 15733521     Source Type: Journal    
DOI: 10.1007/s10865-009-9241-4     Document Type: Article

References (54)

1. Aiken, L. S., & West, S. G. (1991). Multiple regression: Testing and interpreting interactions. Thousand Oaks, CA: Sage.
2. al'Absi, M., Buchanan, T. W., Marrero, A., & Lovallo, W. R. (1999). Sex differences in pain perception and cardiovascular responses in persons with parental history of hypertension. Pain, 83, 331-338.
3. al'Absi, M., France, C., Harju, A., France, J., & Wittmers, L. (2006). Adrenocortical and nociceptive responses to opioid blockade in hypertension-prone men and women. Psychosomatic Medicine, 68, 292-298.
4. al'Absi, M., Petersen, K. L., & Wittmers, L. E. (2000). Blood pressure but not parental history for hypertension predicts pain perception in women. Pain, 88, 61-68.
5. al'Absi, M., Wittmers, L. E., Ellestad, D., Nordehn, G., Kim, S. W., Kirschbaum, C., et al. (2004). Sex differences in pain and hypothalamic- pituitary-adrenocortical responses to opioid blockade. Psychosomatic Medicine, 66, 198-206.
6. Bandura, A., Cioffi, D., Taylor, C. B., & Brouillard, M. E. (1988). Perceived self-efficacy in coping with cognitive stressors and opioid activation. Journal of Personality and Social Psychology, 55, 479-488.
7. Bragdon, E. E., Light, K. C., Costello, N. L., Sigurdsson, A., Bunting, S., Bhalang, K., et al. (2002). Group differences in pain modulation: pain-free women compared to pain-free men and to women with TMD. Pain, 96, 227-237.
8. Brody, S., Angrilli, A., Weiss, U., Birbaumer, N., Mini, A., Veit, R., et al. (1997). Somatosensory evoked potentials during baroreceptor stimulation in chronic low back pain patients and normal controls. International Journal of Psychophysiology, 25, 201-210.
9. Bruehl, S., Carlson, C. R., & McCubbin, J. A. (1992). The relationship between pain sensitivity and blood pressure in normotensives. Pain, 48, 463-467.
10. Bruehl, S., & Chung, O. Y. (2004). Interactions between the cardiovascular and pain regulatory systems: An updated review of mechanisms and possible alterations in chronic pain. Neuroscience and Biobehavioral Reviews, 28, 395-414.
11. Bruehl, S., Chung, O. Y., Diedrich, L., Diedrich, A., & Robertson, D. (2008). The relationship between resting blood pressure and acute pain sensitivity: Effects of chronic pain and alpha-2 adrenergic blockade. Journal of Behavioral Medicine, 31, 71-80.
12. Bruehl, S., Chung, O. Y., Ward, P., & Johnson, B. (2004). Endogenous opioids and chronic pain intensity: Interactions with level of disability. Clinical Journal of Pain, 20, 283-292.
13. Bruehl, S., Chung, O. Y., Ward, P., Johnson, B., & McCubbin, J. A. (2002). The relationship between resting blood pressure and acute pain sensitivity in healthy normotensives and chronic back pain sufferers: The effects of opioid blockade. Pain, 100, 191-201.
14. Bruehl, S., Dengler-Crish, C. M., Smith, C. A., & Walker, L. S. (in press). Hypoalgesia related to elevated resting blood pressure is absent in adolescents and young adults with a history of functional abdominal pain. Pain.
15. Bruehl, S., McCubbin, J. A., & Harden, R. N. (1999). Theoretical review: Altered pain regulatory systems in chronic pain. Neuroscience and Biobehavioral Reviews, 23, 877-890.
16. Burns, J. W., Bruehl, S., Chung, O. Y., Magid, E., Chont, M., Goodlad, J. K., et al. (2009). Endogenous opioids may buffer effects of anger arousal on sensitivity to subsequent pain. Pain, 146, 276-282.
17. Chung, O. Y., Bruehl, S., Diedrich, L., Diedrich, A., Chont, M., & Robertson, D. (2008). Baroreflex sensitivity associated hypoal- gesia in healthy states is altered by chronic pain. Pain, 138, 87-97.
18. Cohen, J. (1988). Statistical power analysis for the behavioral sciences (Second Edition ed.). Hillsdale, NJ: Lawrence Erlbaum.
19. Ditto, B., Pihl, R. O., Seguin, J. R., Boulerice, B., & Tremblay, R. E. (1998). Risk of hypertension and pain sensitivity in adolescent boys. Health Psychology, 17, 249-254.
20. Edwards, R. R., & Fillingim, R. B. (2001). Age-associated differences in responses to noxious stimuli. Journal of Gerontology Series A: Biological Sciences and Medical Sciences, 56, M18-M185.
21. Edwards, L., McIntyre, D., Carroll, D., Ring, C., France, C. R., & Martin, U. (2003). Effects of artificial and natural baroreceptor stimulation on nociceptive responding and pain. Psychophysiology, 40, 762-769.
22. Edwards, L., Ring, C., McIntyre, D., & Carroll, D. (2001). Modulation of the human nociceptive flexion reflex across the cardiac cycle. Psychophysiology, 38, 712-718.
23. Engebretson, T. O., Matthews, K. A., & Scheier, M. F. (1989). Relations between anger expression and cardiovascular reactivity: Reconciling inconsistent findings through a matching hypothesis. Journal of Personality and Social Psychology, 57, 513-521.
24. Fillingim, R. B., & Maixner, W. (1996). The influence of resting blood pressure and gender on pain responses. Psychosomatic Medicine, 58, 326-332.
25. Fillingim, R. B., & Ness, T. J. (2000). Sex-related hormonal influences on pain and analgesic responses. Neuroscience and Biobehavioral Reviews, 24, 485-501.
26. France, C. R., al'Absi, M., Ring, C., France, J. L., Brose, J., Spaeth, D., et al. (2005). Assessment of opiate modulation of pain and nociceptive responding in young adults with a parental history of hypertension. Biological Psychology, 70, 168-174.
27. Frew, A. K., & Drummond, P. D. (2007). Negative affect, pain and sex: The role of endogenous opioids. Pain, 132(Suppl 1), S77-S85.
28. Frew, A. K., & Drummond, P. D. (2008). Stress-evoked opioid release inhibits pain in major depressive disorder. Pain, 139, 284-292.
29. Frew, A. K., & Drummond, P. D. (2009). Opposite effects of opioid blockade on the blood pressure-pain relationship in depressed and non-depressed participants. Pain, 142, 68-74.
30. Girdler, S. S., Koo-Loeb, J., Pedersen, C. A., Brown, H. J., & Maixner, W. (1998). Blood pressure-related hypoalgesia in bulimia nervosa. Psychosomatic Medicine, 62, 517-523.
31. Guasti, L., Catteneo, R., Daneri, A., Bianchi, L., Gaudio, G., Regazzi, M., et al. (1996). Endogenous beta-endorphins in hypertension: Correlation with 24-hour ambulatory blood pressure. Journal of the American College of Cardiology, 28, 1243-1248.
32. Lewkowski, M. D., Young, S. N., Ghosh, S., & Ditto, B. (2008). Effects of opioid blockade on the modulation of pain and mood by sweet taste and blood pressure in young adults. Pain, 135, 75-81.
33. Maixner, W., Fillingim, R., Kincaid, S., Sigurdsson, A., & Harris, M. B. (1997). Relationship between pain sensitivity and resting arterial blood pressure in patients with painful temporomandibular disorders. Psychosomatic Medicine, 59, 503-511.
34. Maixner, W., & Randich, A. (1984). Role of the right vagal nerve trunk in antinociception. Brain Research, 298, 374-377.
35. Maixner, W., Touw, K. B., Brody, M. J., Gebhart, G. F., & Long, J. P. (1982). Factors influencing the altered pain perception in the spontaneously hypertensive rat. Brain Research, 237, 137-145.
36. Maurset, A., Skoglung, L. A., Hustveit, O., Klepstad, P., & Oye, I. (1992). A new version of the ischemic tourniquet pain test. Methods and Findings in Experimental and Clinical Pharmacology, 13, 643-647.
37. McCubbin, J. A., & Bruehl, S. (1994). Do endogenous opioids mediate the relationship between blood pressure and pain sensitivity in normotensives? Pain, 57, 63-67.
38. McCubbin, J. A., Helfer, S. G., Switzer, F. S., 3rd, Galloway, C., & Griffith, W. V. (2006). Opioid analgesia in persons at risk for hypertension. Psychosomatic Medicine, 68, 116-120.
39. Melzack, R. (1987). The short form of the McGill Pain Questionnaire. Pain, 30, 191-197.
40. Naranjo, J. R., & Fuentes, J. A. (1985). Association between hypoalgesia and hypertension in rats after short-term isolation. Neuropharmacology, 24, 167-171.
41. Page, G. D., & France, C. R. (1997). Objective evidence of decreased pain perception in normotensives at risk for hypertension. Pain, 73, 173-180.
42. Randich, A., & Maixner, W. (1984). Interactions between cardiovascular and pain regulatory systems. Neuroscience and Biobehavioral Reviews, 8, 343-367.
43. Ring, C., France, C. R., al'Absi, M., Edwards, L., McIntyre, D., Carroll, D., et al. (2008). Effects of naltrexone on electrocutaneous pain in patients with hypertension compared to normotensive individuals. Biological Psychology, 77, 191-196.
44. Rosa, C., Ghione, S., Mezzasalma, L., Pellegrini, M., Fasolo, B., Giaconi, S., et al. (1988). Relationship between pain sensitivity, cardiovascular reactivity to cold pressor test, and indexes of activity of the adrenergic and opioid system. Clinical and Experimental Hypertension, A10(Suppl. 1), 383-390.
45. Sheps, D. S., Bragdon, E. E., Gray, T. F., Ballenger, M., Usedom, J. E., & Maixner, W. (1992). Relationship between systemic hypertension and pain perception. American Journal of Cardiology, 70, 3F-5F.
46. Sitsen, J. M., & DeJong, W. (1983). Hypoalgesia in genetically hypertensive rats (SHR) is absent in rats with experimental hypertension. Hypertension, 5, 185-190.
47. Sitsen, J., & DeJong, W. (1984). Observations on pain perception and hypertension in spontaneously hypertensive rats. Clinical and Experimental Hypertension, A6, 1345-1356.
48. Smith, Y. R., Stohler, C. S., Nichols, T. E., Bueller, J. A., Koeppe, R. A., & Zubieta, J. K. (2006). Pronociceptive and antinociceptive effects of estradiol through endogenous opioid neurotransmission in women. Journal of Neuroscience, 26, 5777-5785.
49. Sprenger, T., Berthele, A., Platzer, S., Boecker, H., & Tölle, T. R. (2005). What to learn from in vivo opioidergic brain imaging? European Journal of Pain, 9, 117-121.
50. Straneva, P. A., Maixner, W., Light, K. C., Pedersen, C. A., Costello, N. L., & Girdler, S. S. (2002). Menstrual cycle, beta-endorphins, and pain sensitivity in premenstrual dysphoric disorder. Health Psychology, 21, 358-367.
51. Taylor, B. R., Roderick, R. E., & Basbaum, A. I. (2000). Brainstem noradrenergic control of nociception is abnormal in spontaneously hypertensive rats. Neuroscience Letters, 291, 139-142.
52. Tsukamoto, K., Sved, A. F., Ito, S., Komatsu, K., & Kanmatsue, K. (2000). Enhanced serotonin-mediated responses in the nucleus tractus solitarius of spontaneously hypertensive rats. Brain Research, 863, 1-8.
53. Zamir, N., Simantov, R., & Segal, M. (1980). Pain sensitivity and opioid activity in genetically and experimentally hypertensive rats. Brain Research, 184, 299-310.
54. Zubieta, J. K., Dannals, R. F., & Frost, J. J. (1999). Gender and age influences on human mu-opioid receptor binding measured by PET. American Journal of Psychiatry, 156, 842-848.