Anthranilic acid replacements in a niacin receptor agonist

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 11, 2010, Pages 3426-3430

  Schmidt, Darby ^a   Smenton, Abigail ^a   Raghavan, Subharekha ^a   Shen, Hong ^a   Ding, Fa Xiang ^a   Carballo Jane, Ester ^a   Luell, Silvi ^a   Ciecko, Tanya ^a   Holt, Tom G ^a   Wolff, Michael ^a   Taggart, Andrew ^a   Wilsie, Larissa ^a   Krsmanovic, Mihajlo ^a   Ren, Ning ^a   Blom, Daniel ^a   Cheng, Kang ^a   McCann, Peggy E ^a   Waters, M Gerard ^a   Tata, James ^a   Colletti, Steven ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

Anthranilic acid; Atherosclerosis; Coronary disease; GPR109A; HDL; Niacin receptor

Indexed keywords

ANTHRANILIC ACID DERIVATIVE; NIACIN RECEPTOR AGONIST; NICOTINIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; DRUG ACTIVITY; DRUG BIOAVAILABILITY; DRUG CLEARANCE; DRUG EFFICACY; DRUG HALF LIFE; DRUG RECEPTOR BINDING; DRUG STRUCTURE; DRUG SYNTHESIS; HYDROLYSIS; MAXIMUM PLASMA CONCENTRATION; MOUSE; NONHUMAN;

ANTHRANILIC ACIDS; BIOLOGICAL AVAILABILITY; NIACIN; RECEPTORS, DRUG;

EID: 77953284809     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2010.04.001     Document Type: Article

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