Scalable synthesis of a new dihydroxylated intermediate for tetrodotoxin and its analogues

Synthesis

Volumn , Issue 12, 2010, Pages 1992-1998

  Satake, Yoshiki ^a   Nishikawa, Toshio ^a   Hiramatsu, Takeshi ^a   Araki, Hiroshi ^a   Isobe, Minoru ^a  

^a NAGOYA UNIVERSITY   (Japan)

Author keywords

Diels Alder reaction; Hydroxylation; Neighboring group participation; Overman rearrangement; Tetrodotoxin

Indexed keywords

AMINO FUNCTIONALITY; CYCLOHEXENES; DIELS-ALDER REACTION; HYDROXY GROUPS; ISOPRENOL; NOVEL INTERMEDIATES; OVERMAN REARRANGEMENT; SCALABLE SYNTHESIS;

HYDROXYLATION; OLEFINS;

SYNTHESIS (CHEMICAL);

AMIDE; BROMOLEVOGLUCOSENONE; CARBOHYDRATE DERIVATIVE; CYCLOHEXENE DERIVATIVE; GUANIDINE; HYDROXYL GROUP; ISOPRENALINE; TETRODOTOXIN; TETRODOTOXIN DERIVATIVE; TRICHLOROACETAMIDE; UNCLASSIFIED DRUG;

ARTICLE; CHEMICAL REACTION; CHEMICAL STRUCTURE; DIELS ALDER REACTION; HYDROXYLATION; OVERMAN REARRANGEMENT; REACTION ANALYSIS; SYNTHESIS;

EID: 77953251544     PISSN: 00397881     EISSN: 1437210X     Source Type: Journal    
DOI: 10.1055/s-0029-1218747     Document Type: Article

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