Clinical and epidemiologic characteristics of children hospitalized with 2009 pandemic H1N1 influenza a infection

Pediatric Infectious Disease Journal

Volumn 29, Issue 7, 2010, Pages 591-594

  Kumar, Swati ^a,b,c   Havens, Peter L ^b,c   Chusid, Michael J ^b,c   Willoughby Jr , Rodney E ^b,c   Simpson, Pippa ^b   Henrickson, Kelly J ^a,b,c  

^a Midwest Respiratory Virus Program (MRVP)   (United States)

^b MEDICAL COLLEGE OF WISCONSIN   (United States)

^c CHILDREN S HOSPITAL OF WISCONSIN   (United States)

Author keywords

H1N1; influenza; pandemic; pediatric

Indexed keywords

ADRENALIN; ANTIINFECTIVE AGENT; ANTIVIRUS AGENT; CEFEPIME; CEFOTAXIME; CLINDAMYCIN; CORTICOSTEROID; HYPERTENSIVE FACTOR; NORADRENALIN; OSELTAMIVIR; PNEUMOCOCCUS VACCINE; STEROID; VANCOMYCIN; OXYGEN;

ADULT RESPIRATORY DISTRESS SYNDROME; ARTICLE; ARTIFICIAL VENTILATION; ASTHMA; BACTERIAL INFECTION; BRONCHIECTASIS; CHILD; CHILD HOSPITALIZATION; CHILDHOOD DISEASE; CHROMOSOME ABERRATION; CHRONIC LUNG DISEASE; CHRONIC OBSTRUCTIVE LUNG DISEASE; COGNITIVE DEFECT; COUGHING; DISEASE ASSOCIATION; DISSEMINATED INTRAVASCULAR CLOTTING; EXTRACORPOREAL OXYGENATION; FEBRILE CONVULSION; FEMALE; FEVER; HEALTH CARE COST; HEART DISEASE; HEMOGLOBINOPATHY; HIGH RISK PATIENT; HOSPITAL ADMISSION; HUMAN; HYPOVOLEMIC SHOCK; HYPOXEMIA; IMMUNE DEFICIENCY; INFLUENZA; INFLUENZA VIRUS A H1N1; INFLUENZA VIRUS A H1N1 INFECTION; INTENSIVE CARE UNIT; KIDNEY DISEASE; KIDNEY FAILURE; LEUKOPENIA; LIVER FAILURE; LUNG HYPOPLASIA; LYMPHOCYTOPENIA; MAJOR CLINICAL STUDY; MALE; MEDICAL RECORD REVIEW; MIXED INFECTION; MORTALITY; MULTIPLE ORGAN FAILURE; NEOPLASM; NEUROMUSCULAR DISEASE; NEUTROPENIA; PANDEMIC; PNEUMOCOCCAL INFECTION; PRESCHOOL CHILD; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RESPIRATORY TRACT DISEASE; RETROSPECTIVE STUDY; RHINORRHEA; SCHOOL CHILD; SEIZURE; SEPSIS; SHOCK; SUBGLOTTIC STENOSIS; TRACHEOMALACIA; UNITED STATES; VOCAL CORD PARALYSIS; ADOLESCENT; AGE DISTRIBUTION; ECONOMICS; EPIDEMIC; ETHNIC GROUP; HOSPITALIZATION; INFANT; INFLUENZA, HUMAN; INTENSIVE CARE; ISOLATION AND PURIFICATION; PATHOLOGY; PNEUMONIA, BACTERIAL; SEX RATIO; VIROLOGY; YOUNG ADULT;

ADOLESCENT; AGE DISTRIBUTION; ANTI-BACTERIAL AGENTS; ANTIVIRAL AGENTS; CHILD; CHILD, PRESCHOOL; DISEASE OUTBREAKS; ETHNIC GROUPS; FEMALE; HEALTH CARE COSTS; HOSPITALIZATION; HUMANS; INFANT; INFLUENZA A VIRUS, H1N1 SUBTYPE; INFLUENZA, HUMAN; INTENSIVE CARE; MALE; OXYGEN; PNEUMONIA, BACTERIAL; RESPIRATION, ARTIFICIAL; RETROSPECTIVE STUDIES; SEX DISTRIBUTION; WISCONSIN; YOUNG ADULT;

EID: 77953251118     PISSN: 08913668     EISSN: 15320987     Source Type: Journal    
DOI: 10.1097/INF.0b013e3181d73e32     Document Type: Article

References (18)

1. Centers for Disease Control and Prevention. Swine influenza A (H1N1) infection in two children\southern California, March-April 2009. MMWR Morb Mortal Wkly Rep. 2009;58:400-402.
2. Wisconsin Human Cases of H1N1 Influenza Infection. Available at: http://pandemic.wisconsin.gov/category.asp?linkcatid=3191&linkid= 1567&locid= 106.
3. Kumar S, Chusid MJ, Willoughby RE, et al. Introduction of a Novel Swine-Origin Influenza A (H1N1) Virus into Milwaukee, Wisconsin in 2009. Viruses. 2009;1:72-83.
4. Kumar S, Chusid MJ, Willoughby RE, et al. Epidemiologic observations from passive and targeted surveillance during the first wave of the 2009 H1N1 influenza pandemic in Milwaukee, WI. Viruses. In press
5. Centers for Disease Control and Prevention. Hospitalized patients with Novel Influenza A (H1N1) virus infection. California, April-May, 2009. MMWR Morb Mortal Wkly Rep. 2009;58:536-541.
6. Jain S, Kamimoto L, Bramley AM, et al. The 2009 Pandemic Influenza A (H1N1) Virus Hospitalizations Investigation Team. Hospitalized patients with 2009 H1N1 influenza in the United States, April-June 2009. N Engl J Med. 2009;361:1935-1944.
7. Beck ET, Jurgens LA, Kehl SC, et al. Development of a rapid automated influenza A, influenza B, and RSV A/B multiplex real-time RT-PCR assay and its use during the 2009 H1N1 swine-origin influenza virus (S-OIV) epidemic in Milwaukee, Wisconsin. JMol Diagn. 2010;12:74-81.
8. Bose ME, Beck ET, Ledeboer N, et al. Rapid semi-automated subtyping of influenza during the 2009 swine-origin influenza A H1N1 virus epidemic in Milwaukee, Wisconsin. J Clin Microbiol. 2009;47:2779-2786.
9. He J, Bose ME, Beck ET, et al. Rapid multiplex RT-PCR typing of influenza A and B and subtyping of influenza A into H1, 2, 3, 5, 7, 9, N1 (human), N1 (animal), N2 and N7 including typing of novel swine-origin influenza A (H1N1) virus during the current 2009 outbreak in Milwaukee, WI. J Clin Microbiol. 2009;47:2772-2778.
10. Coffin SE, Zaoutis TE, Rosenquist AB, et al. Incidence, complications, and risk factors for prolonged stay in children hospitalized with community-acquired influenza. Pediatrics. 2007;119:740-748.
11. Ampofo K, Gesteland PH, Bender J, et al. Epidemiology, complications, and cost of hospitalization in children with laboratory-confirmed influenza infection. Pediatrics. 2006;118:2409-2417.
12. Izurieta HS, Thompson WW, Kramarz P, et al. Influenza and the rates of hospitalization for respiratory diseases among infants and young children. N Engl J Med. 2000;342:232-239
13. Overweight and Obesity. http://www.cdc.gov/obesity/stateprograms/ fundedstates/wisconsin.html.
14. Ogden CL, Carroll MD, Flegal KM. High body mass index for age among US children and adolescents, 2003-2006. JAMA. 2008;299:2401-2405.
15. Centers for Disease Control and Prevention. Intensive-care patients with severe novel influenza A (H1N1) virus infection\Michigan, June 2009. MMWR Morb Mortal Wkly Rep. 2009; 58: 749-752.
16. Finelli L, Fiore A, Dhara R, et al. Influenza-associated pediatric mortality in the United States: increase of Staphylococcus aureus coinfec-tion. Pediatrics. 2008;122:805-811.
17. Centers for Disease Control and Prevention. Surveillance for pediatric deaths associated with 2009 pandemic influenza a (H1N1) virus infection in United States, April-August. MMWR Morb Mortal Wkly Rep. 2009;58:941-947.
18. Keren R, Zaoutis TE, Saddlemire S, et al. Direct medical cost of influenza-related hospitalizations in children. Pediatrics. 2006;118:e1321- e1327.