Sertoli Leydig cell ovarian tumour and gastric polyps as presenting features of Peutz-Jeghers syndrome

Pediatric Blood and Cancer

Volumn 55, Issue 1, 2010, Pages 206-207

  Howell, Lisa ^a   Bader, Abdulgader ^a   Mullassery, Dhanya ^a   Losty, Paul ^a   Auth, Marcus ^a   Kokai, George ^a  

^a ALDER HEY CHILDREN'S NHS FOUNDATION TRUST   (United Kingdom)

Author keywords

Cytogenetics; Paediatric oncology; Peutz Jeghers syndrome; Rare tumours

Indexed keywords

PROTEIN KINASE LKB1;

ANDROBLASTOMA; ARTICLE; CASE REPORT; CHILD; COLONOSCOPY; COMPUTER ASSISTED TOMOGRAPHY; DISEASE COURSE; FAMILY HISTORY; FATHER; GENE DELETION; HAMARTOMA; HUMAN; HUMAN TISSUE; MALE; OVARY TUMOR; PEUTZ JEGHERS SYNDROME; PRECOCIOUS PUBERTY; PRESCHOOL CHILD; PRIORITY JOURNAL; SCREENING; STK11 GENE; STOMACH POLYP; TUMOR SUPPRESSOR GENE;

CHILD, PRESCHOOL; FEMALE; GASTRIC MUCOSA; GENE DELETION; HAMARTOMA; HUMANS; OVARIAN NEOPLASMS; PEUTZ-JEGHERS SYNDROME; POLYPS; PROTEIN-SERINE-THREONINE KINASES; SERTOLI-LEYDIG CELL TUMOR; STOMACH NEOPLASMS;

EID: 77953241923     PISSN: 15455009     EISSN: 15455017     Source Type: Journal    
DOI: 10.1002/pbc.22433     Document Type: Article

References (7)

1. Amos CI, Keitheri-Cheteri MB, Sabripour M, et al. Genotype - phenotype correlations in Peutz-Jeghers syndrome. J Med Genet 2004;41:327-333. (Pubitemid 38608514)
2. Jeghers H, McKusick J, Katz KH. Generalized intestinal polyposis and melanin spots on oral mucosa, lips and digits: Syndrome of diagnostic significance. N Eng J Med 1949;241:1031-1036.
3. Giardiello FM, Brensinger JD, Tersmette AC, et al. Very high risk of cancer in familial Peutz - Jeghers syndrome. Gastroenterology 2000;119:1447-1453.
4. Lim W, Olschwang S, Keller JJ, et al. Relative frequency and morphology of cancers in STK11 mutation carriers. Gastroenterology 2004;126:1788-1794. (Pubitemid 38736344)
5. Young RH. Sex cord - stromal tumors of the ovary and testis: Their similarities and differences with consideration of selected problems. Mod Pathol 2005;18:S81-S98. Review.
6. De Leng WWJ, Jansen M, Carvalho R, et al. Genetic defects underlying Peutz - Jeghers syndrome (PJS) and exclusion of polarity-associated MARK/Par 1 gene family as potential PJS candidates. Clin Genet 2007;72:568-573. (Pubitemid 350131065)
7. Gibbon D. Conservative management of sex cord stromal tumors with annular tubules of the ovary in women with Peutz - Jeghers syndrome. J Pediatr Hematol Oncol 2005;27:630-632.