An in vitro assay system as a potential replacement for the histamine sensitisation test for acellular pertussis based combination vaccines

Vaccine

Volumn 28, Issue 21, 2010, Pages 3714-3721

  Yuen, Chun Ting ^a   Horiuchi, Yoshinobu ^b   Asokanathan, Catpagavalli ^a   Cook, Sarah ^a   Douglas Bardsley, Alexandra ^a   Ochiai, Masaki ^c   Corbel, Michael ^a   Xing, Dorothy ^a  

^a NATIONAL INSTITUTE FOR BIOLOGICAL STANDARDS AND CONTROL   (United Kingdom)

^b PHARMACEUTICALS AND MEDICAL DEVICES AGENCY   (Japan)

^c NATIONAL INSTITUTE OF INFECTIOUS DISEASES   (Japan)

Author keywords

Acellular pertussis vaccine; Carbohydrate binding; Enzymatic HPLC assay; Histamine sensitisation assay

Indexed keywords

HISTAMINE; PERTUSSIS TOXIN; PERTUSSIS VACCINE;

ARTICLE; ASIA; ASSAY; BINDING ASSAY; BIOLOGICAL ACTIVITY; CONTROLLED STUDY; DRUG SCREENING; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; MATHEMATICAL ANALYSIS; PRIORITY JOURNAL; PROVOCATION TEST; TEMPERATURE MEASUREMENT;

ADP-RIBOSYLATION FACTORS; ANIMAL TESTING ALTERNATIVES; ANIMALS; BIOLOGICAL ASSAY; CARBOHYDRATES; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; FEMALE; HISTAMINE; MICE; MODELS, THEORETICAL; PERTUSSIS VACCINE; REGRESSION ANALYSIS; VACCINES, ACELLULAR; VACCINES, COMBINED;

EID: 77953232787     PISSN: 0264410X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.vaccine.2010.03.009     Document Type: Article

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