Berberine suppresses intestinal disaccharidases with beneficial metabolic effects in diabetic states, evidences from in vivo and in vitro study

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 381, Issue 4, 2010, Pages 371-381

  Liu, Li ^a   Yu, Yun Li ^a   Yang, Jian Song ^b   Li, Yang ^a,b   Liu, Yao Wu ^a,c   Liang, Yan ^a   Liu, Xiao Dong ^a   Xie, Lin ^a   Wang, Guang Ji ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

^b GLAXOSMITHKLINE   (China)

^c XUZHOU MEDICAL UNIVERSITY   (China)

Author keywords

Berberine; Diabetes mellitus; Disaccharidase; PKA; Sucrase isomaltase complex

Indexed keywords

ACARBOSE; BERBERINE; CYCLIC AMP DEPENDENT PROTEIN KINASE; MALTOSE; MESSENGER RNA; N [2 (4 BROMOCINNAMYLAMINO)ETHYL] 5 ISOQUINOLINESULFONAMIDE; SUCROSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARBOHYDRATE ANALYSIS; CARBOHYDRATE METABOLISM; CELL STRAIN CACO 2; CONCENTRATION RESPONSE; CONTROLLED STUDY; DIABETES MELLITUS; DOWN REGULATION; EXPERIMENTAL RAT; GENE EXPRESSION; GLUCOSE BLOOD LEVEL; GLYCEMIC CONTROL; IN VITRO STUDY; IN VIVO STUDY; MALE; NONHUMAN; NUCLEOTIDE SEQUENCE; RAT; STREPTOZOCIN DIABETES;

ACARBOSE; ANIMALS; BERBERINE; BLOOD GLUCOSE; CACO-2 CELLS; CYCLIC AMP-DEPENDENT PROTEIN KINASES; DIABETES MELLITUS, EXPERIMENTAL; DISACCHARIDASES; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; HYPOGLYCEMIC AGENTS; INTESTINES; MALE; MALTOSE; RATS; RATS, SPRAGUE-DAWLEY; RNA, MESSENGER; STREPTOZOCIN; SUCRASE-ISOMALTASE COMPLEX; SUCROSE;

EID: 77953231411     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-010-0502-0     Document Type: Article

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