Changes in bone microarchitecture and biomechanical properties in the th3 thalassemia mouse are associated with decreased bone turnover and occur during the period of bone accrual

Calcified Tissue International

Volumn 86, Issue 6, 2010, Pages 484-494

  Vogiatzi, Maria G ^a   Tsay, Jaime ^a   Verdelis, Kostas ^b   Rivella, Stefano ^a   Grady, Robert W ^a   Doty, Stephen ^b   Giardina, Patricia J ^a   Boskey, Adele L ^b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b HOSPITAL FOR SPECIAL SURGERY   (United States)

Author keywords

Animal model; Bone histology histomorphometry; Bone turnover; Ineffective erythropoiesis; Metabolic bone diseases; Remodeling; Thalassemia

Indexed keywords

CATHEPSIN K; HEMOGLOBIN BETA CHAIN; OSTEOCALCIN;

AGE; ANEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BETA THALASSEMIA; BIOMECHANICS; BLOOD TRANSFUSION; BONE DISEASE; BONE MARROW; BONE STRUCTURE; BONE TURNOVER; CONTROLLED STUDY; CORTICAL BONE; DISEASE SEVERITY; EMBRYO; FETUS; GENE DELETION; HETEROZYGOTE; MORPHOMETRICS; MOUSE; MOUSE STRAIN; NONHUMAN; OSSIFICATION; OSTEOLYSIS; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RIGIDITY; TH3 MOUSE; THALASSEMIA MAJOR; THICKNESS; TRABECULAR BONE;

ANIMALS; BIOMECHANICS; BONE AND BONES; BONE REMODELING; ERYTHROPOIESIS; MICE; MICE, INBRED C57BL; OSTEOPOROSIS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECTROSCOPY, FOURIER TRANSFORM INFRARED; THALASSEMIA; TOMOGRAPHY, X-RAY COMPUTED;

EID: 77953230034     PISSN: 0171967X     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00223-010-9365-0     Document Type: Article

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