Clinical significance and regulation of the costimulatory molecule B7-H3 in human colorectal carcinoma

Cancer Immunology, Immunotherapy

Volumn 59, Issue 8, 2010, Pages 1163-1171

  Sun, Jing ^a   Chen, Lu Jun ^a   Zhang, Guang Bo ^b   Jiang, Jing Ting ^b   Zhu, Ming ^a   Tan, Yan ^b   Wang, Hai Tao ^b   Lu, Bin Feng ^c   Zhang, Xue Guang ^a  

^a MEDICAL COLLEGE OF SOOCHOW UNIVERSITY   (China)

^b SOOCHOW UNIVERSITY   (China)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

B7 H3; Colorectal carcinoma; Tumor immune surveillance; Tumor Infiltrating lymphocytes; Tumor necrosis factor

Indexed keywords

B7 ANTIGEN; TUMOR NECROSIS FACTOR ALPHA;

ADAPTIVE IMMUNITY; ADULT; ANTIGEN EXPRESSION; ARTICLE; CANCER CELL CULTURE; CANCER GRADING; CANCER GROWTH; CANCER STAGING; CANCER TISSUE; COLORECTAL CARCINOMA; COLORECTAL SURGERY; CONTROLLED STUDY; DISTANT METASTASIS; FEMALE; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNE RESPONSE; IMMUNOHISTOCHEMISTRY; IMMUNOSURVEILLANCE; LYMPH NODE METASTASIS; LYMPHOCYTIC INFILTRATION; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; PROGNOSIS; PROTEIN SECRETION; T LYMPHOCYTE; TUMOR LOCALIZATION; TUMOR VOLUME;

ANTIGENS, CD; CACO-2 CELLS; COLORECTAL NEOPLASMS; DISEASE PROGRESSION; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOLOGIC SURVEILLANCE; LYMPHOCYTES, TUMOR-INFILTRATING; MALE; MIDDLE AGED; NEOPLASM STAGING; RECEPTORS, IMMUNOLOGIC; TUMOR NECROSIS FACTOR-ALPHA;

EID: 77953229339     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-010-0841-1     Document Type: Article

References (41)

1. J Weitz M Koch J Debus T Hohler PR Galle MW Buchler 2005 Colorectal cancer Lancet 365 9454 153 165 10.1016/S0140-6736(05)17706-X 15639298 (Pubitemid 40091806)
2. Z Dong Y Qiao L Li Y Chen R Wang T Lei 2002 Report of Chinese cancer control strategy J Chin Cancer Res 11 6 250 260
3. LM Coussens Z Werb 2002 Inflammation and cancer Nature 420 6917 860 867 10.1038/nature01322 1:CAS:528:DC%2BD38XpsFygtb4%3D 12490959 (Pubitemid 36019639)
4. F Pages A Berger M Camus F Sanchez-Cabo A Costes R Molidor B Mlecnik A Kirilovsky M Nilsson D Damotte T Meatchi P Bruneval PH Cugnenc Z Trajanoski WH Fridman J Galon 2005 Effector memory T cells, early metastasis, and survival in colorectal cancer N Engl J Med 353 25 2654 2666 10.1056/NEJMoa051424 1:CAS:528:DC%2BD2MXhtlarsrrE 16371631 (Pubitemid 41817714)
5. JS Bolton GM Fuhrman 2000 Survival after resection of multiple bilobar hepatic metastases from colorectal carcinoma Ann Surg 231 5 743 751 10.1097/00000658-200005000-00015 1:STN:280:DC%2BD3c3jtFCktA%3D%3D 10767796 (Pubitemid 30249836)
6. H Vogelsang S Haas C Hierholzer U Berger JR Siewert H Prauer 2004 Factors influencing survival after resection of pulmonary metastases from colorectal cancer Br J Surg 91 8 1066 1071 10.1002/bjs.4602 1:STN:280: DC%2BD2czot1Chsw%3D%3D 15286972 (Pubitemid 39070825)
7. AH Sharpe GJ Freeman 2002 The B7-CD28 superfamily Nat Rev Immunol 2 2 116 126 10.1038/nri727 1:CAS:528:DC%2BD38XitFSnu7s%3D 11910893
8. RJ Greenwald GJ Freeman AH Sharpe 2005 The B7 family revisited Annu Rev Immunol 23 515 548 10.1146/annurev.immunol.23.021704.115611 15771580 (Pubitemid 40563179)
9. H Dong G Zhu K Tamada L Chen 1999 B7-H1, a third member of the B7 family, co-stimulates T-cell proliferation and interleukin-10 secretion Nat Med 5 12 1365 1369 10.1038/70932 1:CAS:528:DyaK1MXnvFCqt74%3D 10581077
10. Y Latchman CR Wood T Chernova D Chaudhary M Borde I Chernova Y Iwai AJ Long JA Brown R Nunes EA Greenfield K Bourque VA Boussiotis LL Carter BM Carreno N Malenkovich H Nishimura T Okazaki T Honjo AH Sharpe GJ Freeman 2001 PD-L2 is a second ligand for PD-1 and inhibits T cell activation Nat Immunol 2 3 261 268 10.1038/85330 1:CAS:528:DC%2BD3MXhvVaksrc%3D 11224527 (Pubitemid 33706004)
11. SK Yoshinaga JS Whoriskey SD Khare U Sarmiento J Guo T Horan G Shih M Zhang MA Coccia T Kohno A Tafuri-Bladt D Brankow P Campbell D Chang L Chiu T Dai G Duncan GS Elliott A Hui SM McCabe S Scully A Shahinian CL Shaklee G Van TW Mak G Senaldi 1999 T-cell co-stimulation through B7RP-1 and ICOS Nature 402 6763 827 832 10.1038/45582 1:CAS:528:DC%2BD3cXptlCq 10617205
12. AI Chapoval J Ni JS Lau RA Wilcox DB Flies D Liu H Dong GL Sica G Zhu K Tamada L Chen 2001 B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production Nat Immunol 2 3 269 274 10.1038/85339 1:CAS:528: DC%2BD3MXhvVaksLg%3D 11224528 (Pubitemid 33706005)
13. GL Sica IH Choi G Zhu K Tamada SD Wang H Tamura AI Chapoval DB Flies J Bajorath L Chen 2003 B7-H4, a molecule of the B7 family, negatively regulates T cell immunity Immunity 18 6 849 861 10.1016/S1074-7613(03)00152-3 1:CAS:528:DC%2BD3sXltFals70%3D 12818165 (Pubitemid 36776432)
14. Y Ohigashi M Sho Y Yamada Y Tsurui K Hamada N Ikeda T Mizuno R Yoriki H Kashizuka K Yane F Tsushima N Otsuki H Yagita M Azuma Y Nakajima 2005 Clinical significance of programmed death-1 ligand-1 and programmed death-1 ligand-2 expression in human esophageal cancer Clin Cancer Res 11 8 2947 2953 10.1158/1078-0432.CCR-04-1469 1:CAS:528:DC%2BD2MXjtlejt7k%3D 15837746 (Pubitemid 40525197)
15. J Sun K Xu C Wu Y Wang Y Hu Y Zhu Y Chen Q Shi G Yu X Zhang 2007 PD-L1 expression analysis in gastric carcinoma tissue and blocking of tumor-associated PD-L1 signaling by two functional monoclonal antibodies Tissue Antigens 69 1 19 27 10.1111/j.1399-0039.2006.00701.x 1:CAS:528:DC%2BD2sXitV2jsLc%3D 17212704 (Pubitemid 46025335)
16. J Konishi K Yamazaki M Azuma I Kinoshita H Dosaka-Akita M Nishimura 2004 B7-H1 expression on non-small cell lung cancer cells and its relationship with tumor-infiltrating lymphocytes and their PD-1 expression Clin Cancer Res 10 15 5094 5100 10.1158/1078-0432.CCR-04-0428 1:CAS:528:DC%2BD2cXmtlSit7Y%3D 15297412 (Pubitemid 39106851)
17. J Hamanishi M Mandai M Iwasaki T Okazaki Y Tanaka K Yamaguchi T Higuchi H Yagi K Takakura N Minato T Honjo S Fujii 2007 Programmed cell death 1 ligand 1 and tumor-infiltrating CD8+ T lymphocytes are prognostic factors of human ovarian cancer Proc Natl Acad Sci USA 104 9 3360 3365 10.1073/pnas.0611533104 1:CAS:528:DC%2BD2sXjtVWlt7s%3D 17360651 (Pubitemid 46364164)
18. H Ghebeh S Mohammed A Al-Omair A Qattan C Lehe G Al-Qudaihi N Elkum M Alshabanah S Bin Amer A Tulbah D Ajarim T Al-Tweigeri S Dermime 2006 The B7-H1 (PD-L1) T lymphocyte-inhibitory molecule is expressed in breast cancer patients with infiltrating ductal carcinoma: correlation with important high-risk prognostic factors Neoplasia 8 3 190 198 10.1593/neo.05733 1:CAS:528: DC%2BD28XovVKlurs%3D 16611412 (Pubitemid 43671234)
19. I Kryczek S Wei G Zhu L Myers P Mottram P Cheng L Chen G Coukos W Zou 2007 Relationship between B7-H4, regulatory T cells, and patient outcome in human ovarian carcinoma Cancer Res 67 18 8900 8905 10.1158/0008-5472.CAN-07-1866 1:CAS:528:DC%2BD2sXhtVCit7nP 17875732 (Pubitemid 47437467)
20. AE Krambeck RH Thompson H Dong CM Lohse ES Park SM Kuntz BC Leibovich ML Blute JC Cheville ED Kwon 2006 B7-H4 expression in renal cell carcinoma and tumor vasculature: associations with cancer progression and survival Proc Natl Acad Sci USA 103 27 10391 10396 10.1073/pnas.0600937103 1:CAS:528: DC%2BD28XntlOntr8%3D 16798883 (Pubitemid 44051177)
21. B Tringler S Zhuo G Pilkington KC Torkko M Singh MS Lucia DE Heinz J Papkoff KR Shroyer 2005 B7-h4 is highly expressed in ductal and lobular breast cancer Clin Cancer Res 11 5 1842 1848 10.1158/1078-0432.CCR-04-1658 1:CAS:528:DC%2BD2MXitVKrs7Y%3D 15756008 (Pubitemid 40471848)
22. T Nomi M Sho T Akahori K Hamada A Kubo H Kanehiro S Nakamura K Enomoto H Yagita M Azuma Y Nakajima 2007 Clinical significance and therapeutic potential of the programmed death-1 ligand/programmed death-1 pathway in human pancreatic cancer Clin Cancer Res 13 7 2151 2157 10.1158/1078-0432.CCR-06-2746 1:CAS:528:DC%2BD2sXjs12rtL4%3D 17404099 (Pubitemid 46649885)
23. W Zou L Chen 2008 Inhibitory B7-family molecules in the tumour microenvironment Nat Rev Immunol 8 6 467 477 10.1038/nri2326 1:CAS:528:DC%2BD1cXmt1Ojt74%3D 18500231 (Pubitemid 351733418)
24. Y Sun Y Wang J Zhao M Gu R Giscombe AK Lefvert X Wang 2006 B7-H3 and B7-H4 expression in non-small-cell lung cancer Lung Cancer 53 2 143 151 10.1016/j.lungcan.2006.05.012 16782226 (Pubitemid 43994236)
25. H Ghebeh E Barhoush A Tulbah N Elkum T Al-Tweigeri S Dermime 2008 FOXP3+ Tregs and B7-H1+/PD-1+ T lymphocytes co-infiltrate the tumor tissues of high-risk breast cancer patients: implication for immunotherapy BMC Cancer 8 57 10.1186/1471-2407-8-57 18294387 (Pubitemid 351516593)
26. Q Gao XY Wang SJ Qiu I Yamato M Sho Y Nakajima J Zhou BZ Li YH Shi YS Xiao Y Xu J Fan 2009 Overexpression of PD-L1 significantly associates with tumor aggressiveness and postoperative recurrence in human hepatocellular carcinoma Clin Cancer Res 15 3 971 979 10.1158/1078-0432.CCR-08-1608 1:CAS:528: DC%2BD1MXht1Ontr8%3D 19188168
27. M Hashiguchi H Kobori P Ritprajak Y Kamimura H Kozono M Azuma 2008 Triggering receptor expressed on myeloid cell-like transcript 2 (TLT-2) is a counter-receptor for B7-H3 and enhances T cell responses Proc Natl Acad Sci USA 105 30 10495 10500 10.1073/pnas.0802423105 1:CAS:528:DC%2BD1cXpsFKkurg%3D 18650384
28. DV Prasad T Nguyen Z Li Y Yang J Duong Y Wang C Dong 2004 Murine B7-H3 is a negative regulator of T cells J Immunol 173 4 2500 2506 1:CAS:528: DC%2BD2cXmt1Olt7s%3D 15294965
29. R Castriconi A Dondero R Augugliaro C Cantoni B Carnemolla AR Sementa F Negri R Conte MV Corrias L Moretta A Moretta C Bottino 2004 Identification of 4Ig-B7-H3 as a neuroblastoma-associated molecule that exerts a protective role from an NK cell-mediated lysis Proc Natl Acad Sci USA 101 34 12640 12645 10.1073/pnas.0405025101 1:CAS:528:DC%2BD2cXnsVentrg%3D 15314238 (Pubitemid 39122076)
30. G Chavin Y Sheinin PL Crispen SA Boorjian TJ Roth L Rangel ML Blute TJ Sebo DJ Tindall ED Kwon RJ Karnes 2009 Expression of immunosuppresive B7-H3 ligand by hormone-treated prostate cancer tumors and metastases Clin Cancer Res 15 6 2174 2180 10.1158/1078-0432.CCR-08-2262 1:CAS:528:DC%2BD1MXjtF2ru7g%3D 19276267
31. G Zhang Y Xu X Lu H Huang Y Zhou B Lu X Zhang 2008 Soluble CD276 (B7-H3) is released from monocytes, dendritic cells and activated T cells and is detectable in normal human serum Immunology 123 4 538 546 10.1111/j.1365-2567. 2007.02723.x 1:CAS:528:DC%2BD1cXjtFCnurk%3D 18194267 (Pubitemid 351280967)
32. TJ Roth Y Sheinin CM Lohse SM Kuntz X Frigola BA Inman AE Krambeck ME McKenney RJ Karnes ML Blute JC Cheville TJ Sebo ED Kwon 2007 B7-h3 ligand expression by prostate cancer: a novel marker of prognosis and potential target for therapy Cancer Res 67 16 7893 7900 10.1158/0008-5472.CAN-07-1068 1:CAS:528:DC%2BD2sXptVGlt7g%3D 17686830 (Pubitemid 47281385)
33. X Zang RH Thompson HA Al-Ahmadie AM Serio VE Reuter JA Eastham PT Scardino P Sharma JP Allison 2007 B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome Proc Natl Acad Sci USA 104 49 19458 19463 10.1073/pnas.0709802104 1:CAS:528: DC%2BD1cXisVOhtg%3D%3D 18042703
34. PL Crispen Y Sheinin TJ Roth CM Lohse SM Kuntz X Frigola RH Thompson SA Boorjian H Dong BC Leibovich ML Blute ED Kwon 2008 Tumor cell and tumor vasculature expression of B7-H3 predict survival in clear cell renal cell carcinoma Clin Cancer Res 14 16 5150 5157 10.1158/1078-0432.CCR-08-0536 1:CAS:528:DC%2BD1cXpslKgtbk%3D 18694993
35. G Zhang Y Xu X Lu H Huang Y Zhou B Lu X Zhang 2009 Diagnosis value of serum B7-H3 expression in non-small cell lung cancer Lung Cancer 66 2 245 249 10.1016/j.lungcan.2009.01.017 19269710
36. M Karin Y Cao FR Greten ZW Li 2002 NF-kappaB in cancer: from innocent bystander to major culprit Nat Rev Cancer 2 4 301 310 10.1038/nrc780 1:CAS:528:DC%2BD38XivFGqt7k%3D 12001991
37. WK Suh BU Gajewska H Okada MA Gronski EM Bertram W Dawicki GS Duncan J Bukczynski S Plyte A Elia A Wakeham A Itie S Chung J Da Costa S Arya T Horan P Campbell K Gaida PS Ohashi TH Watts SK Yoshinaga MR Bray M Jordana TW Mak 2003 The B7 family member B7-H3 preferentially down-regulates T helper type 1-mediated immune responses Nat Immunol 4 9 899 906 10.1038/ni967 1:CAS:528:DC%2BD3sXms12gtL8%3D 12925852 (Pubitemid 37098661)
38. M Egeblad Z Werb 2002 New functions for the matrix metalloproteinases in cancer progression Nat Rev Cancer 2 3 161 174 10.1038/nrc745 1:CAS:528:DC%2BD38Xis1KktL8%3D 11990853
39. J Galon A Costes F Sanchez-Cabo A Kirilovsky B Mlecnik C Lagorce-Pages M Tosolini M Camus A Berger P Wind F Zinzindohoue P Bruneval PH Cugnenc Z Trajanoski WH Fridman F Pages 2006 Type, density, and location of immune cells within human colorectal tumors predict clinical outcome Science 313 5795 1960 1964 10.1126/science.1129139 1:CAS:528:DC%2BD28XhtVSnsrnK 17008531 (Pubitemid 44498003)
40. A Gregorio MV Corrias R Castriconi A Dondero M Mosconi C Gambini A Moretta L Moretta C Bottino 2008 Small round blue cell tumours: diagnostic and prognostic usefulness of the expression of B7-H3 surface molecule Histopathology 53 1 73 80 10.1111/j.1365-2559.2008.03070.x 1:STN:280:DC%2BD1cvktFSjtg%3D%3D 18613926 (Pubitemid 351861985)
41. S Kim TO Keku C Martin J Galanko JT Woosley JC Schroeder JA Satia S Halabi RS Sandler 2008 Circulating levels of inflammatory cytokines and risk of colorectal adenomas Cancer Res 68 1 323 328 10.1158/0008-5472.CAN-07-2924 1:CAS:528:DC%2BD1cXoslWq 18172326 (Pubitemid 351380135)