Electroencephalographic seizures after neonatal cardiac surgery with high-flow cardiopulmonary bypass

Anesthesia and Analgesia

Volumn 110, Issue 6, 2010, Pages 1680-1685

  Andropoulos, Dean B ^a,b   Mizrahi, Eli M ^a,b   Hrachovy, Richard A ^a,b,c   Stayer, Stephen A ^a,b   Stark, Ann R ^a,b   Heinle, Jeffrey S ^a,d   McKenzie, Emmitt D ^a,d   Dickerson, Heather A ^a,b   Meador, Marcie R ^b   Fraser Jr , Charles D ^a,d  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b TEXAS CHILDREN S HOSPITAL   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

^d Congenital Heart Surgery Service ^*  (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

BENZODIAZEPINE; FENTANYL; ISOFLURANE; LORAZEPAM; MIDAZOLAM; MORPHINE;

ARTICLE; BRAIN INFARCTION; BRAIN METABOLISM; BRAIN OXYGENATION; BRAIN PERFUSION; BRAIN VENTRICLE; CARDIOPULMONARY BYPASS; CLINICAL PROTOCOL; CONTINUOUS INFUSION; CONTROLLED STUDY; DISEASE SEVERITY; EEG ABNORMALITY; ELECTROENCEPHALOGRAPHIC SEIZURE; FEMALE; HEMATOCRIT; HUMAN; INCIDENCE; INFANT; MAJOR CLINICAL STUDY; MALE; NEWBORN SURGERY; OXYGEN SATURATION; OXYGENATION; PERIOPERATIVE PERIOD; PH; POSTOPERATIVE HEMORRHAGE; PRIORITY JOURNAL; RISK FACTOR; SEIZURE; SINGLE DRUG DOSE; VIDEORECORDING; WHITE MATTER INJURY;

ANESTHESIA; ANESTHETICS; BRAIN CHEMISTRY; CARDIAC SURGICAL PROCEDURES; CARDIOPULMONARY BYPASS; CEREBROVASCULAR CIRCULATION; ELECTROENCEPHALOGRAPHY; FEMALE; HEART DEFECTS, CONGENITAL; HEART VENTRICLES; HUMANS; HYPNOTICS AND SEDATIVES; INFANT, NEWBORN; MAGNETIC RESONANCE IMAGING; MALE; OXYGEN; OXYGEN CONSUMPTION; PAIN, POSTOPERATIVE; PERFUSION; POSTOPERATIVE CARE; POSTOPERATIVE COMPLICATIONS; SEIZURES; VIDEO RECORDING;

EID: 77953201097     PISSN: 00032999     EISSN: None     Source Type: Journal    
DOI: 10.1213/ANE.0b013e3181dd5a58     Document Type: Article

References (32)

1. Silverstein FS, Jensen FE. Neonatal seizures. Ann Neurol 2007;62:112-120
2. Newburger JW, Jonas RA, Wernovsky G, Wypij D, Hickey PR, Kuban KC, Farrell DM, Holmes GL, Helmers SL, Constantinou J. A comparison of the perioperative neurologic effects of hypothermic circulatory arrest versus low-flow cardiopulmonary bypass in infant heart surgery. N Engl J Med 1993;329:1057-1064
3. Gaynor JW, Nicolson SC, Jarvik GP, Wernovsky G, Montenegro LM, Burnham NB, Hartman DM, Louie A, Spray TL, Clancy RR. Increasing duration of deep hypothermic circulatory arrest is associated with an increased incidence of postoperative electroencephalographic seizures. J Thorac Cardiovasc Surg 2005;130:1278-1286
4. Fraser CD Jr, Andropoulos DB. Principles of antegrade cerebral perfusion during arch reconstruction in newborns/infants. Semin Thorac Cardiovasc Surg Pediatr Card Surg Annu 2008;49-56
5. Hofer A, Haizinger B, Geiselseder G, Mair R, Rehak P, Gombotz H. Monitoring of selective antegrade cerebral perfusion using near infrared spectroscopy in neonatal aortic arch surgery. Eur J Anaesthesiol 2005;22:293-298
6. Karl TR, Hall S, Ford G, Kelly EA, Brizard CP, Mee RB, Weintraub RG, Cochrane AD, Glidden D. Arterial switch with full-flow cardiopulmonary bypass and limited circulatory arrest: neurodevelopmental outcome. J Thorac Cardiovasc Surg 2004;127:213-222
7. Andropoulos DB, Hunter JV, Nelson DP, Stayer SA, Stark AR, McKenzie ED, Heinle JS, Graves DE, Fraser CD Jr. Brain immaturity is associated with MRI brain injury before and after neonatal cardiac surgery with high-flow bypass and cerebral oxygenation monitoring. J Thorac Cardiovasc Surg 2010;139:543-556
8. Andropoulos DB, Stayer SA, McKenzie ED, Fraser CD Jr. Regional low-flow perfusion provides comparable blood flow and oxygenation to both cerebral hemispheres during neonatal aortic arch reconstruction. J Thorac Cardiovasc Surg 2003;126:1712-1717
9. Andropoulos DB, Stayer SA, Diaz LK, Ramamoorthy C. Neurologic monitoring for congenital heart surgery. Anesth Analg 2004;99:1365-1375
10. Mizrahi EM, Hrachovy RA, Kellaway P. Techniques of recording the neonatal electroencephalogram. In: Mizrahi EM, Hrachovy RA, Kellaway P, eds. Atlas of Neonatal Electroencephalography. Philadelphia: Lippincott Williams & Williams, 2004:5-12
11. Mizrahi EM, Kellaway P. Characterization and classification of neonatal seizures. Neurology 1987;37:1837-1844
12. Dent CL, Spaeth JP, Jones BV, Schwartz SM, Glauser TA, Hallinan B, Pearl JM, Khoury PR, Kurth CD. Brain magnetic resonance imaging abnormalities after the Norwood procedure using regional cerebral perfusion. J Thorac Cardiovasc Surg 2006;131:190-197
13. Newcombe RG. Two-sided confidence intervals for the single proportion: comparison of seven methods. Stat Med 1998;17: 857-872
14. Kussman BD, Wypij D, DiNardo JA, Newburger JW, Mayer JE Jr, del Nido PJ, Bacha EA, Pigula F, McGrath E, Laussen PC. Cerebral oximetry during infant cardiac surgery: evaluation and relationship to early postoperative outcome. Anesth Analg 2009;108:1122-1131
15. Kurth CD, Levy WJ, McCann J. Near-infrared spectroscopy cerebral oxygen saturation thresholds for hypoxia-ischemia in piglets. J Cereb Blood Flow Metab 2002;22:335-341
16. Hou X, Ding H, Teng Y, Zhou C, Tang X, Li S, Ding H. Research on the relationship between brain anoxia at different regional oxygen saturations and brain damage using nearinfrared spectroscopy. Physiol Meas 2007;28:1251-1265
17. Mulla H, McCormack P, Lawson G, Firmin RK, Upton DR. Pharmacokinetics of midazolam in neonates undergoing extracorporeal membrane oxygenation. Anesthesiology 2003;99: 275-282 (Pubitemid 36909552)
18. de Wildt SN, de Hoog M, Vinks AA, van der Giesen E, van den Anker JN. Population pharmacokinetics and metabolism of midazolam in pediatric intensive care patients. Crit Care Med 2003;31:1952-1958
19. Peeters MY, Prins SA, Knibbe CA, Dejongh J, Mathôt RA, Warris C, van Schaik RH, Tibboel D, Danhof M. Pharmacokinetics and pharmacodynamics of midazolam and metabolites in nonventilated infants after craniofacial surgery. Anesthesiology 2006;105:1135-1146
20. Boylan GB, Rennie JM, Chorley G, Pressler RM, Fox GF, Farrer K, Morton M, Binnie CD. Second-line anticonvulsant treatment of neonatal seizures: a video-EEG monitoring study. Neurology 2004;62:486-488
21. Castro Conde JR, Hernández Borges AA, Doménech Martínez E, González Campo C, Perera Soler R. Midazolam in neonatal seizures with no response to phenobarbital. Neurology 2005; 64:876-879
22. Sirsi D, Nangia S, LaMothe J, Kosofsky BE, Solomon GE. Successful management of refractory neonatal seizures with midazolam. J Child Neurol 2008;23:706-709
23. Helmers SL, Wypij D, Constantinou JE, Newburger JW, Hickey PR, Carrazana EJ, Barlow JK, Kuban KC, Holmes GL. Perioperative electroencephalographic seizures in infants undergoing repair of complex congenital cardiac defects. Electroencephalogr Clin Neurophysiol 1997;102:27-36
24. du Plessis AJ, Jonas RA, Wypij D, Hickey PR, Riviello J, Wessel DL, Roth SJ, Burrows FA, Walter G, Farrell DM, Walsh AZ, Plumb CA, del Nido P, Burke RP, Castaneda AR, Mayer JE Jr, Newburger JW. Perioperative effects of alpha-stat versus pHstat strategies for deep hypothermic cardiopulmonary bypass in infants. J Thorac Cardiovasc Surg 1997;114:991-1000
25. Clancy RR, Sharif U, Ichord R, Spray TL, Nicolson S, Tabbutt S, Wernovsky G, Gaynor JW. Electrographic neonatal seizures after infant heart surgery. Epilepsia 2005;46:84-90
26. Young GB, da Silva OP. Effects of morphine on the electroencephalograms of neonates: a prospective, observational study. Clin Neurophysiol 2000;111:1955-1960
27. Clancy RR. Summary proceedings from the neurology group on neonatal seizures. Pediatrics 2006;117(3 Part 2):S23-7
28. Thibeault-Eybalin MP, Lortie A, Carmant L. Neonatal seizures: do they damage the brain? Pediatr Neurol 2009;40:175-180
29. Tekgul H, Gauvreau K, Soul J, Murphy L, Robertson R, Stewart J, Volpe J, Bourgeois B, du Plessis AJ. The current etiologic profile and neurodevelopmental outcome of seizures in term newborn infants. Pediatrics 2006;117:1270-1280
30. Rappaport LA, Wypij D, Bellinger DC, Helmers SL, Holmes GL, Barnes PD, Wernovsky G, Kuban KC, Jonas RA, Newburger JW. Relation of seizures after cardiac surgery in early infancy to neurodevelopmental outcome. Boston Circulatory Arrest Study group. Circulation 1998;97:773-779
31. Bellinger DC, Newburger JW, Wypij D, Kuban KC, duPlesssis AJ, Rappaport LA. Behaviour at eight years in children with surgically corrected transposition: The Boston Circulatory Arrest Trial. Cardiol Young 2009;19:86-97
32. Gaynor JW, Jarvik GP, Bernbaum J, Gerdes M, Wernovsky G, Burnham NB, D'Agostino JA, Zackai E, McDonald-McGinn DM, Nicolson SC, Spray TL, Clancy RR. The relationship of postoperative electrographic seizures to neurodevelopmental outcome at 1 year of age after neonatal and infant cardiac surgery. J Thorac Cardiovasc Surg 2006;131:181-189