메뉴 건너뛰기




Volumn 37, Issue 4, 2010, Pages 1801-1814

A microarray study of altered gene expression in colorectal cancer cells after treatment with immunomodulatory drugs: Differences in action in vivo and in vitro

Author keywords

Colorectal cancer; Gene expression; Immunomodulatory drug; In vitro; In vivo

Indexed keywords

CHEMOKINE RECEPTOR CCR4; CHEMOKINE RECEPTOR CCR5; CONTACTIN; EPIDERMAL GROWTH FACTOR; EPIDERMAL GROWTH FACTOR RECEPTOR; FIBROBLAST GROWTH FACTOR 1; FIBROBLAST GROWTH FACTOR RECEPTOR 1; G PROTEIN COUPLED RECEPTOR; GELATINASE B; GLYCEROL KINASE; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOMODULATING AGENT; INTERLEUKIN 2; INTERLEUKIN 6; LENALIDOMIDE; LIPOCALIN; MITOGEN ACTIVATED PROTEIN KINASE 1; NOTCH RECEPTOR; POMALIDOMIDE; PROTEIN BAX; PROTEIN BCL 2; RING FINGER PROTEIN; SCATTER FACTOR; SEMINAL VESICLE SECRETORY PROTEIN; THALIDOMIDE; TRANSFORMING GROWTH FACTOR BETA RECEPTOR 1; TRANSFORMING GROWTH FACTOR BETA1; VASCULOTROPIN RECEPTOR 1; WNT PROTEIN; BIOLOGICAL MARKER; DRUG DERIVATIVE; IMMUNOLOGIC FACTOR;

EID: 77953171709     PISSN: 03014851     EISSN: 15734978     Source Type: Journal    
DOI: 10.1007/s11033-009-9614-3     Document Type: Article
Times cited : (29)

References (33)
  • 1
    • 41149168649 scopus 로고    scopus 로고
    • Lenalidomide for the treatment of B-cell malignancies
    • doi:10.1200/JCO.2007.14.5367
    • Chanan-Khan AA, Cheson BD (2008) Lenalidomide for the treatment of B-cell malignancies. J Clin Oncol 26:1544-1552. doi:10.1200/JCO.2007.14.5367
    • (2008) J Clin Oncol , vol.26 , pp. 1544-1552
    • Chanan-Khan, A.A.1    Cheson, B.D.2
  • 2
    • 47249145259 scopus 로고    scopus 로고
    • Lenalidomide and its role in the management of multiple myeloma
    • doi:10.1586/14737140.8.6.865
    • Falco P, Cavallo F, Larocca A et al (2008) Lenalidomide and its role in the management of multiple myeloma. Expert Rev Anticancer Ther 8:865-874. doi:10.1586/14737140.8.6.865
    • (2008) Expert Rev Anticancer Ther , vol.8 , pp. 865-874
    • Falco, P.1    Cavallo, F.2    Larocca, A.3
  • 3
    • 1942534043 scopus 로고    scopus 로고
    • The evolution of thalidomide and its IMiD derivatives as anticancer agents
    • doi:10.1038/nrc1323
    • Bartlett JB, Dredge K, Dalgleish AG (2004) The evolution of thalidomide and its IMiD derivatives as anticancer agents. Nat Rev Cancer 4:314-322. doi:10.1038/nrc1323
    • (2004) Nat Rev Cancer , vol.4 , pp. 314-322
    • Bartlett, J.B.1    Dredge, K.2    Dalgleish, A.G.3
  • 4
    • 20144375457 scopus 로고    scopus 로고
    • Orally administered lenalidomide (CC-5013) is anti-angiogenic in vivo and inhibits endothelial cell migration and Akt phosphorylation in vitro
    • doi:10.1016/j.mvr.2005.01.002
    • Dredge K, Horsfall R, Robinson SP et al (2005) Orally administered lenalidomide (CC-5013) is anti-angiogenic in vivo and inhibits endothelial cell migration and Akt phosphorylation in vitro. Microvasc Res 69:56-63. doi:10.1016/j.mvr.2005.01.002
    • (2005) Microvasc Res , vol.69 , pp. 56-63
    • Dredge, K.1    Horsfall, R.2    Robinson, S.P.3
  • 5
    • 0037021257 scopus 로고    scopus 로고
    • Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects
    • doi:10.1038/sj.bjc.6600607
    • Dredge K, Marriott JB, Macdonald CD et al (2002) Novel thalidomide analogues display anti-angiogenic activity independently of immunomodulatory effects. Br J Cancer 87:1166-1172. doi:10.1038/sj.bjc.6600607
    • (2002) Br J Cancer , vol.87 , pp. 1166-1172
    • Dredge, K.1    Marriott, J.B.2    Macdonald, C.D.3
  • 6
    • 33749331571 scopus 로고    scopus 로고
    • The thalidomide analogue, CC-4047, induces apoptosis signaling and growth arrest in childhood acute lymphoblastic leukemia cells in vitro and in vivo
    • doi:10.1158/1078-0432.CCR-06-0719
    • Shalapour S, Zelmer A, Pfau M et al (2006) The thalidomide analogue, CC-4047, induces apoptosis signaling and growth arrest in childhood acute lymphoblastic leukemia cells in vitro and in vivo. Clin Cancer Res 12:5526-5532. doi:10.1158/1078-0432.CCR-06-0719
    • (2006) Clin Cancer Res , vol.12 , pp. 5526-5532
    • Shalapour, S.1    Zelmer, A.2    Pfau, M.3
  • 7
    • 33846665934 scopus 로고    scopus 로고
    • Lenalidomide and CC-4047 inhibit the proliferation of malignant B cells while expanding normal CD34+ progenitor cells
    • doi:10.1158/0008-5472.CAN-06-2317
    • Verhelle D, Corral LG, Wong K et al (2007) Lenalidomide and CC-4047 inhibit the proliferation of malignant B cells while expanding normal CD34+ progenitor cells. Cancer Res 67:746-755. doi:10.1158/0008-5472.CAN-06-2317
    • (2007) Cancer Res , vol.67 , pp. 746-755
    • Verhelle, D.1    Corral, L.G.2    Wong, K.3
  • 8
    • 54049156803 scopus 로고    scopus 로고
    • Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma
    • Breitkreutz I, Raab MS, Vallet S, et al. (2008) Lenalidomide inhibits osteoclastogenesis, survival factors and bone-remodeling markers in multiple myeloma. Leukemia 22:1925-1932
    • (2008) Leukemia , vol.22 , pp. 1925-1932
    • Breitkreutz, I.1    Raab, M.S.2    Vallet, S.3
  • 9
    • 3142693456 scopus 로고    scopus 로고
    • S-thalidomide has a greater effect on apoptosis than angiogenesis in a multiple myeloma cell line
    • doi:10.1038/sj.thj.6200351
    • Liu WM, Strauss SJ, Chaplin T et al (2004) s-thalidomide has a greater effect on apoptosis than angiogenesis in a multiple myeloma cell line. Hematol J 5:247-254. doi:10.1038/sj.thj.6200351
    • (2004) Hematol J , vol.5 , pp. 247-254
    • Liu, W.M.1    Strauss, S.J.2    Chaplin, T.3
  • 10
    • 67349107194 scopus 로고    scopus 로고
    • The anticancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells
    • Galustian C, Meyer B, Labarthe MC, et al. (2008) The anticancer agents lenalidomide and pomalidomide inhibit the proliferation and function of T regulatory cells. Cancer Immunol Immunother 58:1033-1045
    • (2008) Cancer Immunol Immunother , vol.58 , pp. 1033-1045
    • Galustian, C.1    Meyer, B.2    Labarthe, M.C.3
  • 11
    • 77955717766 scopus 로고    scopus 로고
    • Inhibition of metastatic potential in colorectal carcinoma in vivo and in vitro using immunomodulatory drugs (IMiDs)
    • (in press)
    • Liu WM, Henry JY, Meyer B, Bartlett JB, Dalgleish AG, Galustian C (in press) Inhibition of metastatic potential in colorectal carcinoma in vivo and in vitro using immunomodulatory drugs (IMiDs). Brit J Cancer
    • Brit J Cancer
    • Liu, W.M.1    Henry, J.Y.2    Meyer, B.3    Bartlett, J.B.4    Dalgleish, A.G.5    Galustian, C.6
  • 12
    • 18544390035 scopus 로고    scopus 로고
    • Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing erythropoiesis and promoting myelopoiesis
    • doi:10.1182/blood-2004-03-0828
    • Koh KR, Janz M, Mapara MY et al (2005) Immunomodulatory derivative of thalidomide (IMiD CC-4047) induces a shift in lineage commitment by suppressing erythropoiesis and promoting myelopoiesis. Blood 105:3833-3840. doi:10.1182/blood-2004-03-0828
    • (2005) Blood , vol.105 , pp. 3833-3840
    • Koh, K.R.1    Janz, M.2    Mapara, M.Y.3
  • 13
    • 0025370870 scopus 로고
    • T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis
    • doi:10.1038/346183a0
    • Ota K, Matsui M, Milford EL et al (1990) T-cell recognition of an immunodominant myelin basic protein epitope in multiple sclerosis. Nature 346:183-187. doi:10.1038/346183a0
    • (1990) Nature , vol.346 , pp. 183-187
    • Ota, K.1    Matsui, M.2    Milford, E.L.3
  • 14
    • 20344365607 scopus 로고    scopus 로고
    • Molecules affecting myelin stability: A novel hypothesis regarding the pathogenesis of multiple sclerosis
    • doi:10.1002/jnr.20420
    • Mastronardi FG, Moscarello MA (2005) Molecules affecting myelin stability: A novel hypothesis regarding the pathogenesis of multiple sclerosis. J Neurosci Res 80:301-308. doi:10.1002/jnr.20420
    • (2005) J Neurosci Res , vol.80 , pp. 301-308
    • Mastronardi, F.G.1    Moscarello, M.A.2
  • 15
    • 0033166025 scopus 로고    scopus 로고
    • Inhibition of TNF-alpha synthesis with thalidomide for prevention of acute exacerbations and altering the natural history of multiple sclerosis
    • doi:10.1054/mehy.1997.0719
    • Sastry PS (1999) Inhibition of TNF-alpha synthesis with thalidomide for prevention of acute exacerbations and altering the natural history of multiple sclerosis. Med Hypotheses 53:76-77.doi:10.1054/mehy.1997.0719
    • (1999) Med Hypotheses , vol.53 , pp. 76-77
    • Sastry, P.S.1
  • 16
    • 1542317449 scopus 로고    scopus 로고
    • Notch regulation of lymphocyte development and function
    • doi:10.1038/ni1045
    • Radtke F, Wilson A, Mancini SJ et al (2004) Notch regulation of lymphocyte development and function. Nat Immunol 5:247-253. doi:10.1038/ni1045
    • (2004) Nat Immunol , vol.5 , pp. 247-253
    • Radtke, F.1    Wilson, A.2    Mancini, S.J.3
  • 17
    • 11244305618 scopus 로고    scopus 로고
    • WNT signalling and haematopoiesis: A WNT-WNT situation
    • doi:10.1038/nri1529
    • Staal FJ, Clevers HC (2005) WNT signalling and haematopoiesis: A WNT-WNT situation. Nat Rev Immunol 5:21-30. doi:10.1038/nri1529
    • (2005) Nat Rev Immunol , vol.5 , pp. 21-30
    • Staal, F.J.1    Clevers, H.C.2
  • 18
    • 22244461524 scopus 로고    scopus 로고
    • Notch signaling from tumor cells: A new mechanism of angiogenesis
    • doi:10.1016/j.ccr.2005.06.013
    • Li JL, Harris AL (2005) Notch signaling from tumor cells: A newmechanism of angiogenesis. Cancer Cell 8:1-3. doi:10.1016/j.ccr.2005.06.013
    • (2005) Cancer Cell , vol.8 , pp. 1-3
    • Li, J.L.1    Harris, A.L.2
  • 19
    • 34748837360 scopus 로고    scopus 로고
    • Networking of WNT, FGF, Notch, BMP, and hedgehog signaling pathways during carcinogenesis
    • doi:10.1007/s12015-007-0006-6
    • Katoh M (2007) Networking of WNT, FGF, Notch, BMP, and Hedgehog signaling pathways during carcinogenesis. Stem Cell Rev 3:30-38. doi:10.1007/s12015-007- 0006-6
    • (2007) Stem Cell Rev , vol.3 , pp. 30-38
    • Katoh, M.1
  • 20
    • 0036433637 scopus 로고    scopus 로고
    • Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/ KDR expression
    • doi:10.1006/mvre.2002.2443
    • Taylor KL, Henderson AM, Hughes CC (2002) Notch activation during endothelial cell network formation in vitro targets the basic HLH transcription factor HESR-1 and downregulates VEGFR-2/ KDR expression. Microvasc Res 64:372-383. doi:10.1006/mvre.2002.2443
    • (2002) Microvasc Res , vol.64 , pp. 372-383
    • Taylor, K.L.1    Henderson, A.M.2    Hughes, C.C.3
  • 21
    • 34547107319 scopus 로고    scopus 로고
    • WNT signaling pathway and stem cell signaling network
    • doi:10.1158/1078-0432.CCR-06-2316
    • Katoh M, Katoh M (2007) WNT signaling pathway and stem cell signaling network. Clin Cancer Res 13:4042-4045. doi:10.1158/1078-0432.CCR-06-2316
    • (2007) Clin Cancer Res , vol.13 , pp. 4042-4045
    • Katoh, M.1    Katoh, M.2
  • 23
    • 51649123319 scopus 로고    scopus 로고
    • Lenalidomide enhances natural killer cell and monocyte-mediated antibody-dependent cellular cytotoxicity of rituximab-treated CD20 + tumor cells
    • doi:10.1158/1078-0432.CCR-07-4405
    • Wu L, Adams M, Carter T et al (2008) Lenalidomide enhances natural killer cell and monocyte-mediated antibody-dependent cellular cytotoxicity of rituximab-treated CD20 + tumor cells.Clin Cancer Res 14:4650-4657. doi:10.1158/1078-0432.CCR-07-4405
    • (2008) Clin Cancer Res , vol.14 , pp. 4650-4657
    • Wu, L.1    Adams, M.2    Carter, T.3
  • 24
    • 0037097595 scopus 로고    scopus 로고
    • Apoptotic signaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: Therapeutic implications
    • doi:10.1182/blood.V99.12.4525
    • Mitsiades N, Mitsiades CS, Poulaki V et al (2002) Apoptotic ignaling induced by immunomodulatory thalidomide analogs in human multiple myeloma cells: Therapeutic implications. Blood 99:4525-4530. doi:10.1182/blood.V99.12.4525
    • (2002) Blood , vol.99 , pp. 4525-4530
    • Mitsiades, N.1    Mitsiades, C.S.2    Poulaki, V.3
  • 25
    • 0347320849 scopus 로고    scopus 로고
    • A novel hypothesis for thalidomideinduced limb teratogenesis: Redox misregulation of the NF-kappaB pathway
    • doi:10.1089/152308604771978291
    • Hansen JM, Harris C (2004) A novel hypothesis for thalidomideinduced limb teratogenesis: redox misregulation of the NF-kappaB pathway. Antioxid Redox Signal 6:1-14. doi:10.1089/152308604771978291
    • (2004) Antioxid Redox Signal , vol.6 , pp. 1-14
    • Hansen, J.M.1    Harris, C.2
  • 26
    • 37449033866 scopus 로고    scopus 로고
    • Positive and negative signaling components involved in TNFalpha-induced NF-kappaB activation
    • doi:10.1016/j.cyto.2007.09.016
    • Li H, Lin X (2008) Positive and negative signaling components involved in TNFalpha-induced NF-kappaB activation. Cytokine 41:1-8. doi:10.1016/j.cyto. 2007.09.016
    • (2008) Cytokine , vol.41 , pp. 1-8
    • Li, H.1    Lin, X.2
  • 27
    • 0037119587 scopus 로고    scopus 로고
    • Stochastic gene expression in a single cell
    • doi:10.1126/science.1070919
    • Elowitz MB, Levine AJ, Siggia ED et al (2002) Stochastic gene expression in a single cell. Science 297:1183-1186. doi:10.1126/science.1070919
    • (2002) Science , vol.297 , pp. 1183-1186
    • Elowitz, M.B.1    Levine, A.J.2    Siggia, E.D.3
  • 28
    • 38149082553 scopus 로고    scopus 로고
    • Epigenetic gene expression noise and phenotypic diversification of clonal cell populations
    • Neildez-Nguyen TM, Parisot A, Vignal C et al (2008) Epigenetic gene expression noise and phenotypic diversification of clonal cell populations. Differentiation 76:33-40
    • (2008) Differentiation , vol.76 , pp. 33-40
    • Neildez-Nguyen, T.M.1    Parisot, A.2    Vignal, C.3
  • 29
    • 0000391746 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis
    • doi:10.1038/35036374
    • Bergers G, Brekken R, McMahon G et al (2000) Matrix metalloproteinase-9 triggers the angiogenic switch during carcinogenesis. Nat Cell Biol 2:737-744. doi:10.1038/35036374
    • (2000) Nat Cell Biol , vol.2 , pp. 737-744
    • Bergers, G.1    Brekken, R.2    McMahon, G.3
  • 30
    • 52049098990 scopus 로고    scopus 로고
    • Enhancing the cytotoxic activity of novel targeted therapies-is there a role for a combinatorial approach?
    • doi:10.2174/157488408784293714
    • Liu WM (2008) Enhancing the cytotoxic activity of novel targeted therapies-is there a role for a combinatorial approach? Curr Clin Pharmacol 3:108-117. doi:10.2174/157488408784293714
    • (2008) Curr Clin Pharmacol , vol.3 , pp. 108-117
    • Liu, W.M.1
  • 31
    • 8444220472 scopus 로고    scopus 로고
    • Gene expression microarray technologies in the development of new therapeutic agents
    • doi:10.1016/j.ejca.2004.07.024
    • Clarke PA, te Poele R, Workman P (2004) Gene expression microarray technologies in the development of new therapeutic agents. Eur J Cancer 40:2560-2591. doi:10.1016/j.ejca.2004.07.024
    • (2004) Eur J Cancer , vol.40 , pp. 2560-2591
    • Clarke, P.A.1    Te Poele, R.2    Workman, P.3
  • 32
    • 51049090172 scopus 로고    scopus 로고
    • Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma
    • doi:10.1158/1078-0432.CCR-07-4568
    • Burington B, Barlogie B, Zhan F et al (2008) Tumor cell gene expression changes following short-term in vivo exposure to single agent chemotherapeutics are related to survival in multiple myeloma. Clin Cancer Res 14:4821-4829. doi:10.1158/1078-0432.CCR-07-4568
    • (2008) Clin Cancer Res , vol.14 , pp. 4821-4829
    • Burington, B.1    Barlogie, B.2    Zhan, F.3
  • 33
    • 47649085380 scopus 로고    scopus 로고
    • Thalidomide and lenalidomide: Mechanism-based potential drug combinations
    • doi:10.1080/10428190802005191
    • Vallet S, Palumbo A, Raje N et al (2008) Thalidomide and lenalidomide: mechanism-based potential drug combinations. Leuk Lymphoma 49:1238-1245. doi:10.1080/10428190802005191
    • (2008) Leuk Lymphoma , vol.49 , pp. 1238-1245
    • Vallet, S.1    Palumbo, A.2    Raje, N.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.