Binding to gangliosides containing N-acetylneuraminic acid is sufficient to mediate the immunomodulatory properties of the nontoxic mucosal adjuvant LT-IIb(T13I)

Clinical and Vaccine Immunology

Volumn 17, Issue 6, 2010, Pages 969-978

  Nawar, Hesham F ^a   Berenson, Charles S ^a   Hajishengallis, George ^b   Takematsu, Hiromu ^c   Mandell, Lorrie ^a   Clare, Ragina L ^a   Connell, Terry D ^a  

^a UNIVERSITY AT BUFFALO   (United States)

^b University of Louisville School of Medicine   (United States)

^c KYOTO UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ENTEROTOXIN LT IIB; ENTEROTOXIN LT IIB(T13I); GAMMA INTERFERON; GANGLIOSIDE; IMMUNOGLOBULIN A; IMMUNOGLOBULIN G; IMMUNOLOGICAL ADJUVANT; INTERLEUKIN 17; INTERLEUKIN 4; INTERLEUKIN 6; N ACETYLNEURAMINIC ACID; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANTIBODY PRODUCTION; ARTICLE; B LYMPHOCYTE; BINDING AFFINITY; CONTROLLED STUDY; CYTOKINE RELEASE; DENDRITIC CELL; DRUG RECEPTOR BINDING; FEMALE; HUMAN; HUMAN CELL; IMMUNE RESPONSE; IMMUNOMODULATION; IMMUNOPOTENTIATION; MONOCYTE; MOUSE; NONHUMAN; PERITONEUM MACROPHAGE; PRIORITY JOURNAL; PROTEIN EXPRESSION; T LYMPHOCYTE; TRANSCRIPTION REGULATION; UPREGULATION;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; B-LYMPHOCYTES; BACTERIAL TOXINS; CYTOKINES; ENTEROTOXINS; ESCHERICHIA COLI PROTEINS; GANGLIOSIDES; HUMANS; IMMUNITY, MUCOSAL; IMMUNIZATION; IMMUNOLOGIC FACTORS; MACROPHAGES, PERITONEAL; MICE; MICE, INBRED C57BL; MONOCYTES; N-ACETYLNEURAMINIC ACID; RECEPTORS, CELL SURFACE;

EID: 77953167145     PISSN: 15566811     EISSN: 1556679X     Source Type: Journal    
DOI: 10.1128/CVI.00076-10     Document Type: Article

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