The upregulation of heat shock protein 47 in human gingival fibroblasts stimulated with cyclosporine A

Journal of Periodontal Research

Volumn 45, Issue 3, 2010, Pages 317-322

  Chang, T Y ^a   Tsai, C H ^b   Chang, Y C ^c  

^a School of Dentistry   (Taiwan)

^b CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^c CHUNG SHAN MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

Author keywords

Cyclosporine A; Gingival fibroblast; Gingival overgrowth; Heat shock protein 47

Indexed keywords

1,3 BUTADIENE DERIVATIVE; 1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; CYCLOSPORIN; ENZYME INHIBITOR; HEAT SHOCK PROTEIN 47; IMMUNOSUPPRESSIVE AGENT; INTERLEUKIN 1ALPHA; MITOGEN ACTIVATED PROTEIN KINASE KINASE; NITRILE; SERPINH1 PROTEIN, HUMAN;

AGGREGATIBACTER ACTINOMYCETEMCOMITANS; ARTICLE; CELL CULTURE; COMPARATIVE STUDY; CYTOLOGY; DOSE RESPONSE; DRUG ANTAGONISM; DRUG EFFECT; ENDOTHELIUM CELL; EPITHELIUM CELL; FIBROBLAST; GINGIVA; GINGIVA OVERGROWTH; HUMAN; IMMUNOHISTOCHEMISTRY; INFLAMMATION; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION; UPREGULATION; WESTERN BLOTTING; ANTAGONISTS AND INHIBITORS; DRUG EFFECTS;

ACTINOBACILLUS ACTINOMYCETEMCOMITANS; BLOTTING, WESTERN; BUTADIENES; CELLS, CULTURED; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOTHELIAL CELLS; ENZYME INHIBITORS; EPITHELIAL CELLS; FIBROBLASTS; GINGIVA; GINGIVAL OVERGROWTH; HSP47 HEAT-SHOCK PROTEINS; HUMANS; IMMUNOHISTOCHEMISTRY; IMMUNOSUPPRESSIVE AGENTS; INFLAMMATION; INTERLEUKIN-1ALPHA; MAP KINASE SIGNALING SYSTEM; MITOGEN-ACTIVATED PROTEIN KINASE KINASES; NITRILES; UP-REGULATION; AGGREGATIBACTER ACTINOMYCETEMCOMITANS;

EID: 77953164387     PISSN: 00223484     EISSN: 16000765     Source Type: Journal    
DOI: 10.1111/j.1600-0765.2009.01238.x     Document Type: Article

References (33)

1. Faulds D, Goa KL, Benfield P. Cyclosporin. A review of its pharmacodynamic and pharmacokinetic properties, and therapeutic use in immunoregulatory disorders. Drugs 1993, 45:953-1040.
2. Mariani G, Calastrini C, Carinci F, Marzola R, Calura G. Ultrastructural features of cyclosporin A-induced gingival hyperplasia. J Periodontol 1993, 64:1092-1097.
3. Marshall RI, Bartold PM. A clinical review of drug-induced gingival overgrowths. Aust Dent J 1999, 44:219-232.
4. Seymour RA, Ellis JS, Thomason JM. Risk factors for drug-induced gingival overgrowth. J Clin Periodontol 2000, 27:217-223.
5. Lin HJ, Tsai CH, Huang FM, Chang YC. The upregulation of type I plasminogen activator inhibitor in human gingival fibroblasts stimulated with cyclosporin A. J Periodontal Res 2007, 42:39-44.
6. Tsai CH, Yang SF, Huang FM, Chang YC. The upregulation of cystatin C in human gingival fibroblasts stimulated with cyclosporin A. J Periodontal Res 2009, 44:459-464.
7. Tsai CH, Chang TY, Chang YC. Upregulation of lysyl oxidase expression in cyclosporin A-induced gingival overgrowth. J Dent Sci 2009, 4:13-17.
8. Whisstock J, Skinner R, Lesk AM. An atlas of serpin conformations. Trends Biochem Sci 1998, 23:63-67.
9. Taguchi T, Razzaque MS. The collagen-specific molecular chaperone Hsp47: is there a role in fibrosis? Trends Mol Med 2007, 13:45-53.
10. Natsume T, Koide T, Yokota S, Hirayoshi K, Nagata K. Interactions between collagen-binding stress protein Hsp47 and collagen. Analysis of kinetic parameters by surface plasmon resonance biosensor. J Biol Chem 1994, 269:31224-31228.
11. Naitoh M, Hosokawa N, Kubota H. Upregulation of Hsp47 and collagen type III in the dermal fibrotic disease, keloid. Biochem Biophys Res Commun 2001, 280:1316-1322.
12. Razzaque MS, Nazneen A, Taguchi T. Immunolocalization of collagen and collagen-binding heat shock protein 47 in fibrotic lung diseases. Mod Pathol 1998, 11:1183-1188.
13. Razzaque MS, Hossain MA, Kohno S, Taguchi T. Bleomycin-induced pulmonary fibrosis in rat is associated with increased expression of collagen-binding heat shock protein (HSP) 47. Virchows Arch 1998, 432:455-460.
14. Yang SF, Tsai CH, Chang YC. The upregulation of heat shock protein 47 expression in human buccal fibroblasts stimulated with arecoline. J Oral Pathol Med 2008, 37:206-210.
15. Martelli-Junior H, Cortrim P, Graner E, Sauk JJ, Coletta RD. Effect of transforming growth factor-B1, interleukin-6, and interferon-r on the expression of type I collagen, heat shock protein 47, matrix metalloproteinase (MMP-1) and MMP-2 by fibroblasts from normal gingival and hereditary gingival fibromatosis. J Periodontol 2003, 74:296-306.
16. Hassell T, Hefti AF. Drug-induced gingival overgrowth: old problem, new problem. Crit Rev Oral Biol Med 1991, 2:103-137.
17. Chang YC, Tsai CH, Yang SH, Liu CM, Chou MY. Induction of cyclooxygenase-2 mRNA and protein expression in human gingival fibroblasts stimulated with nicotine. J Periodontal Res 2003, 38:496-501.
18. Chang YC, Lai CC, Lin LF, Ni WF, Tsai CH. The upregulation of heme oxygenase-1 expression in human gingival fibroblasts stimulated with nicotine. J Periodontal Res 2005, 40:252-257.
19. Chang YC, Yang SF, Lai CC, Liu JY, Hsieh YS. Regulation of matrix metalloproteinases production by cytokines, pharmacological agents, and periodontal pathogens in human periodontal ligament fibroblast cultures. J Periodontal Res 2002, 37:196-203.
20. Seymour RA, Thomason JM, Ellis JS. The pathogenesis of drug-induced gingival overgrowth. J Clin Periodontol 1996, 23:165-175.
21. Trackman PC, Kantarci A. A connective tissue metabolism and gingival overgrowth. Crit Rev Oral Biol Med 2004, 15:165-175.
22. Taguchi T, Razzaque MS. The collagen-specific molecular chaperone Hsp47: is there a role in fibrosis? Trends Mol Med 2006, 13:45-53.
23. Tipton DA, Stricklin GP, Dabbous MKH. Fibroblast heterogeneity in collagenolytic response. J Cell Biochem 1991, 46:152-165.
24. Elias JA, Phipps RP. Fibroblast immune effector function. Pulmonary Fibroblast Heterogeneity 1992, -295. In, ed, Boca Raton, FL, CRC Press Inc
25. Rezzani R, Rodella L, Buffoli B, Giugno L, Stacchiotti A, Bianchi R. Cyclosporine A induces vascular fibrosis and heat shock protein expression in rat. Int Immunopharmacol 2005, 5:169-176.
26. Satoh M, Hirayoshi K, Obara M. Intracellular interaction of collagen-specific stress preotein Hsp47 with newly synthesized procollagen. J Cell Biol 1996, 133:469-483.
27. Nagata K. Expression and function of heat shock protein 47: a collagen-specific molecular chaperone in the endoplasmic reticulum. Matrix Biol 1998, 16:379-386.
28. Schincaglia GP, Forniti F, Cavallini R, Piva R, Calura G, del Senno L. Cyclosporin-A increases type I procollagen production and mRNA level in human gingival fibroblasts in vitro. J Oral Pathol Med 1992, 21:181-185.
29. Fu E, Nieh S, Wikesjo UME. The effect of plaque retention on cyclosporine A-induced gingival overgrowth in rats. J Periodontol 1997, 68:92-98.
30. Listgarten MA. Nature of periodontal diseases: pathogenic mechanisms. J Periodent Res 1987, 22:172-178.
31. Chae HJ, Ha MS, Yun DH. Mechanism of cyclosporine-induced overgrowth in gingival. J Dent Res 2006, 85:515-519.
32. Hagiwara S, Iwasaka H, Matsumoto S, Noguchi T. An antisense oligonucleotide to Hsp47 inhibits paraquat-induced pulmonary fibrosis in rats. Toxicology 2007, 236:199-207.
33. Hagiwara S, Iwasaka H, Matsumoto S, Noguchi T. Antisense oligonucleotide inhibition of heat shock protein (HSP) 47 improves bleomycin-induced pulmonary fibrosis in rats. Respir Res 2007, 10.1186/1465-9921-8-37, doi