Superficial primary small cell carcinoma of the esophagus: Clinicopathological and immunohistochemical analysis of 15 cases

Diseases of the Esophagus

Volumn 23, Issue 2, 2010, Pages 153-159

  Lu, J ^a   Xue, L Y ^a   Lu, N ^a   Zou, S M ^a   Liu, X Y ^a   Wen, P ^a  

^a PEKING UNION MEDICAL COLLEGE   (China)

Author keywords

Esophageal cancer; Immunohistochemistry; Small cell carcinoma; Therapy

Indexed keywords

CARBOPLATIN; CD56 ANTIGEN; CHROMOGRANIN A; CISPLATIN; CYTOKERATIN; CYTOKERATIN 10; CYTOKERATIN 13; CYTOKERATIN 34BETAE12; CYTOKERATIN AE1; CYTOKERATIN AE3; ETOPOSIDE; NEURON SPECIFIC ENOLASE; SYNAPTOPHYSIN; THYROID TRANSCRIPTION FACTOR 1; UNCLASSIFIED DRUG; CK-34 BETA E12; ENOLASE; KERATIN; NUCLEAR PROTEIN; THYROID NUCLEAR FACTOR 1; TRANSCRIPTION FACTOR; TUMOR MARKER;

ABDOMINAL PAIN; ADULT; AGED; ARTICLE; CANCER COMBINATION CHEMOTHERAPY; CANCER DIAGNOSIS; CANCER GROWTH; CANCER RADIOTHERAPY; CANCER STAGING; CLINICAL ARTICLE; CLINICAL FEATURE; CONTINUOUS INFUSION; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; DIFFERENTIAL DIAGNOSIS; DISEASE ASSOCIATION; DISEASE DURATION; DYSPHAGIA; ESOPHAGUS CARCINOMA; ESOPHAGUS INJURY; FEMALE; FOLLOW UP; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MULTIPLE CYCLE TREATMENT; PRIORITY JOURNAL; PROGNOSIS; RETROSTERNAL PAIN; SEX RATIO; SMALL CELL CARCINOMA; SURVIVAL RATE; SURVIVAL TIME; ADJUVANT THERAPY; AGE; CARCINOMA, SMALL CELL; DEGLUTITION DISORDERS; ESOPHAGEAL NEOPLASMS; ESOPHAGUS RESECTION; LYMPH NODE DISSECTION; MIDDLE AGED; RETROSPECTIVE STUDY; SECONDARY; SEX DIFFERENCE; TREATMENT OUTCOME; VERY ELDERLY;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; ANTIGENS, CD56; CARCINOMA, SMALL CELL; CHROMOGRANIN A; DEGLUTITION DISORDERS; ESOPHAGEAL NEOPLASMS; ESOPHAGECTOMY; FEMALE; FOLLOW-UP STUDIES; HUMANS; KERATIN-13; KERATINS; LYMPH NODE EXCISION; MALE; MIDDLE AGED; NEOADJUVANT THERAPY; NUCLEAR PROTEINS; PHOSPHOPYRUVATE HYDRATASE; RETROSPECTIVE STUDIES; SEX FACTORS; SURVIVAL RATE; SYNAPTOPHYSIN; TRANSCRIPTION FACTORS; TREATMENT OUTCOME; TUMOR MARKERS, BIOLOGICAL;

EID: 77953158473     PISSN: 11208694     EISSN: 14422050     Source Type: Journal    
DOI: 10.1111/j.1442-2050.2009.00981.x     Document Type: Article

References (30)

1. Van der heijden H F, Heijdra Y F. Extrapulmonary small cell carcinoma. South Med J 2005; 98: 345-9.
2. Kim K O, Lee H Y, Chun S H et al. Clinical overview of extrapulmonary small cell carcinoma. J Korean Med Sci 2006; 21: 833-7.
3. Pantvaidya G H, Pramesh C S, Deshpande M S, Jambhekar N A, Sharma S, Deshpande R K. Small cell carcinoma of the esophagus: the Tata Memorial Hospital experience. Ann Thorac Surg 2002; 74: 1924-7.
4. Mitani M, Kuwabara Y, Shinoda N, Sato A, Fujii Y. Longterm survivors after the resection of limited esophageal SCC. Dis Esophagus 2000; 13: 259-61.
5. Nemoto K, Zhao H J, Goto T et al. Radiation therapy for limited-stage small-cell esophageal cancer. Am J Clin Oncol 2002; 25: 404-7.
6. Shamelian S O, Nortier J W. Extrapulmonary small-cell carcinoma: report of three cases and update of therapy and prognosis. Neth J Med 2000; 56: 51-5.
7. Makino H, Tajiri T, Onda M et al. Effectiveness of preoperative chemotherapy using carboplatin (CBDCA) and surgery against an esophageal small cell carcinoma. Dis Esophagus 2002; 15: 237-41.
8. Capella C, Solcia E, Sobin L H, Arnold R. Endocrine tumors of the esophagus. In: Hamilton S R, Aaltonen L A, (eds). World Health Organization Classification of Tumors, Pathology & Genetics, Tumors of the Digestive System. Lyon: IARC Press, 2004; 26-7.
9. Travis W, Petersen I, Nicholson S et al. SCC. In: Travis W D, Brambilla E, Müller-Hermelink H K, Harris C C, (eds). World Health Organization Classification of Tumors, Pathology & Genetics, Tumors of the Lung, Pleura, Thymus and Heart. Lyon: IARC Press, 2004; 31-4.
10. Brenner B, Tang L H, Klimstra D S, Kelsen D P. Small-cell carcinoma of the gastrointestinal tract: a review. J Clin Oncol 2004; 22: 2730-9.
11. Takubo K, Nakamura K, Sawabe M et al. Primary undifferentiated small cell carcinoma of the esophagus. Hum Pathol 1999; 30: 216-21.
12. Ugras S, Akpolat N, Er M, Yalcynkaya I, Karayvazm M. Primary composite tumour with bipartite differentiation of the esophagus. Acta Chir Belg 2000; 100: 39-43.
13. Law S Y, Fok M, Lam K Y, Loke S L, Ma L T, Wong J. SCC of the esophagus. Cancer 1994; 73: 2894-9.
14. Medgyesy C D, Wolff R A, Putnam J B, Ajani J A. Small cell carcinoma of the esophagus: the University of Texas M. D. Anderson Cancer Center experience and literature review. Cancer 2000; 88: 262-7.
15. Casas F, Ferrer F, Farrus B, Casals J, Biete A. Primary small cell carcinoma of the esophagus: a review of the literature with emphasis on therapy and prognosis. Cancer 1997; 80: 1366-72.
16. Noguchi T, Takeno S, Kato T et al. Small cell carcinoma of the esophagus; clinicopathological and immunohistochemical analysis of six cases. Dis Esophagus 2003; 16: 252-8.
17. Yun P Y, Zhang M F, Hou J H et al. Primary small cell carcinoma of the esophagus: clinicopathological and immunohistochemical features of 21 cases. BMC Cancer 2007; 7: 38-46.
18. Shy SW, LeeWH, ChouMC, Lai Y S, Tu Y C. Small cell lung carcinoma: clinicopathological, immunohistochemical, and ultrastructural study. J Surg Oncol 1990; 45 (3): 146-61.
19. Deftos L J, Linnoila R I, Carney D N et al. Demonstration of chromogranin A in human neuroendocrine cell lines by immunohistology and immunoassay. Cancer 1988; 62 (1): 92- 7.
20. Lloyd R V, Cano M, Rosa P, Hille A, Huttner W B. Distribution of chromogranin A and secretogranin I (chromogranin B) in neuroendocrine cells and tumors. Am J Pathol 1988; 130: 296-304.
21. Helpap B, Köllermann J. Immunohistochemical analysis of the proliferative activity of neuroendocrine tumors from various organs. Are there indications for a neuroendocrine tumor-carcinoma sequence? Virchows Arch 2001; 438: 86- 91.
22. Hamid Q, Corrin B, Sheppard M N, Huttner W B, Polak J M. Expression of chromogranin A mRNA in SCC of the lung. J Pathol 1991; 163 (4): 293-7.
23. Fabbro D, Di Loreto C, Stamerra O, Beltrami C A, Lonigro R, Damante G. TTF-1 gene expression in human lung tumors. Eur J Cancer 1996; 32A: 512-7.
24. Cheuk W, KwanMY, Suster S, Chan J K. Immunostaining for thyroid transcription factor 1 and cytokeratin 20 aids the distinction of small cell carcinoma from Merkel cell carcinoma, but not pulmonary from extrapulmonary small cell carcinomas. Arch Pathol Lab Med 2001; 125: 228-31.
25. Agoff S N, Lamps LW, Philip A T et al. Thyroid transcription factor-1 is expressed in extrapulmonary small cell carcinomas but not in other extrapulmonary neuroendocrine tumors. Mod Pathol 2000; 13: 238-42.
26. Kaufmann O, Dietel M. Expression of thyroid transcription factor-1 in pulmonary and extrapulmonary small cell carcinomas and other neuroendocrine carcinomas of various primary sites. Histopathology 2000; 36: 415-20.
27. Huncharek M, Muscat J. Small cell carcinoma of the esophagus. The Massachusetts General Hospital experience, 1978 to 1993. Chest 1995; 107: 179-81.
28. Koide N, Saito H, Suzuki A et al. Clinicopathologic features and histochemical analyses of proliferative activity and angiogenesis in small cell carcinoma of the esophagus. J Gastroenterol 2007; 42: 932-8.
29. Sun K L, He J, Cheng G Y, Chai L X. Management of primary cell carcinoma of the esophagus. Chin Med J (Engl) 2007; 120: 355-8.
30. Wang G Q, Jiao G G, Chang F B et al. Long-term results of operation for 420 patients with early squamous cell esophageal carcinoma discovered by screening. Ann Thorac Surg 2004; 77: 1740-4.