Multiplate® whole blood impedance point of care aggregometry: Preliminary reference values in healthy infants, children and adolescents

Klinische Padiatrie

Volumn 222, Issue 3, 2010, Pages 158-163

  Halimeh, S ^a   De Angelis, G ^b   Sander, A ^b   Edelbusch, C ^b   Rott, H ^a   Thedieck, S ^b   Mesters, R ^b   Schlegel, N ^c   Nowak Gottl U ^b  

^a Ambulatory Health Care Center for Coagulation Disorders and Haemophilia   (Germany)

^b UNIVERSITY HOSPITAL MÜNSTER   (Germany)

^c HÔPITAL ROBERT DEBRÉ   (France)

Author keywords

Aggregometry; Children; Impedance; Infants; Platelet function; Reference values

Indexed keywords

ARACHIDONIC ACID; COLLAGEN; RISTOCETIN; THROMBIN RECEPTOR ACTIVATING PEPTIDE 6;

ADOLESCENT; ANALYTIC METHOD; ANALYZER; AREA UNDER THE CURVE; ARTICLE; BLOOD; CHILD; CONTROLLED STUDY; ELECTRIC RESISTANCE; FEMALE; HUMAN; IMPEDANCE AGGREGOMETRY; INFANT; MALE; POINT OF CARE TESTING; PRESCHOOL CHILD; REFERENCE VALUE; SCHOOL CHILD; THROMBOCYTE AGGREGATION; THROMBOCYTE FUNCTION; AGE; BLOOD CLOTTING PARAMETERS; GLANZMANN DISEASE; HOSPITAL INFORMATION SYSTEM; IMPEDANCE; INSTRUMENTATION; PHYSIOLOGY;

ADOLESCENT; AGE FACTORS; CHILD; CHILD, PRESCHOOL; ELECTRIC IMPEDANCE; FEMALE; HUMANS; INFANT; MALE; PLATELET AGGREGATION; PLATELET FUNCTION TESTS; POINT-OF-CARE SYSTEMS; REFERENCE VALUES; THROMBASTHENIA;

EID: 77953157979     PISSN: 03008630     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0030-1249081     Document Type: Article

References (17)

1. Bernstaedt M, Kunze C, Brandt J, etal. Haemophiliac pseudotumor: two case reports of patients with moderate haemophilia A. Klin Padiatr 2009 221 172-173
2. Bolton-Maggs PHB, Chalmers EA, etal. A review of inherited platelet disorders with guidelines for their management on behalf of the UKHCDO. Br J Haematol 2006 135 603-633
3. Born GV, Cross MJ. The aggregation of blood platelets. J Physiol 1963 168 178-195
4. Calatzis A, Leitner M, Panzer S. Monitoring anticoagulation of primary haemostasis. Hämostaseologie 2009 29 279-284
5. Hézard N, Potron G, Schlegel N, etal. Unexpected persistence of platelet hyporeactivity beyond the neonatal period: a flow cytometric study in neonates, infants and older children. Thromb Haemost 2003 90 116-123
6. Hurtaud-Roux MF, Hezard N, Lefranc V, etal. Quantification of the major integrins and P-Selectin in neonatal platelets by flow cytometry. A bicentric study. Thromb Haemost 2001 ISSN0340-6245
7. Kühne T, Ryan G, Blanchette V, etal. Platelet-surface glycoproteins in healthy and preeclamptic mothers and their newborn infants. Pediatr Res 1996 40 876-880
8. Michelson AD, Rajasekhar D, Bednarek FJ, etal. Platelet and platelet-derived microparticle surface factor V/Va binding in whole blood: differences between neonates and adults. Thromb Haemost 2000 84 689-694
9. Mielke CH, Kaneshiro MM, Maher IA, etal. The standardized normal Ivy bleeding time and its prolongation by aspirin. Blood 1969 34 204-215
10. Rajasekhar D, Barnard MR, Bednarek FJ, etal. Platelet hyporeactivity in very low birth weight neonates. Thromb Haemost 1997 77 1002-1007
11. Rajasekhar D, Kestin AS, Bednarek FJ, etal. Neonatal platelets are less reactive than adult platelets to physiological agonists in whole blood. Thromb Haemost 1994 72 957-963
12. Rolf N, Knoefler R, Bugert P, etal. Clinical and laboratory phenotypes associated with the aspirin-like defect: a study in 17 unrelated families. Br J Haematol 2008 144 416-424
13. Scharf RE. Erworbene Plättchenfunktionsstörungen. Pathogenese, Klassifikation, Häufigkeit, Diagnostik und Behandlung. Haemostaseologie 2008 28 299-311
14. Toth O, Calatzis A, Penz S, etal. Multiple electrode aggregometry: A new device to measure platelet aggregation in whole blood. Thromb Haemost 2006 96 781-788
15. Velik-Salchner C, Maier S, Innerhofer P, etal. Point-of Care whole blood impedance aggregometry versus classical light transmission aggregometry for detecting aspirin and Clopidogrel: The results of a pilot study. Anest Analg 2008 107 1798-1806
16. Weinspach S, Siepermann M, Schaper J, etal. Intracranial hemorrhage in a female leading to the diagnosis of severe hemophilia A and Turner syndrome. Klin Padiatr 2009 221 167-171
17. Riess H, Braun G, Brehm G, etal. Critical evaluation of platelet aggregation in whole human blood. Am J Clin Pathol 1986 85 50-56