Necrosisof a skin autograft after short-term treatment with sunitinib in a 14-year-old girl with metastatic alveolar soft part sarcoma of the thigh

Klinische Padiatrie

Volumn 222, Issue 3, 2010, Pages 184-186

  Hanzer, M ^a   Nebl, A ^a   Spendel, S ^a   Pilhatsch, A ^a   Urban, C ^a   Benesch, M ^a  

^a MEDICAL UNIVERSITY OF GRAZ   (Austria)

Author keywords

Alveolar soft part sarcoma; Skin toxicity; Sunitinib; Targeted therapy

Indexed keywords

DOXORUBICIN; EPIDERMAL GROWTH FACTOR RECEPTOR; IFOSFAMIDE; PEGINTERFERON ALPHA2B; PLATELET DERIVED GROWTH FACTOR ALPHA RECEPTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; SUNITINIB; THALIDOMIDE; VASCULOTROPIN RECEPTOR 1; VASCULOTROPIN RECEPTOR 2; VASCULOTROPIN RECEPTOR 3; VINCRISTINE; ANGIOGENESIS INHIBITOR; ANTINEOPLASTIC AGENT; INDOLE DERIVATIVE; PYRROLE DERIVATIVE;

ADOLESCENT; ALVEOLAR SOFT PART SARCOMA; ARTICLE; BONE MARROW BIOPSY; BONE SCINTISCANNING; CANCER RADIOTHERAPY; CANCER SURGERY; CASE REPORT; COMPUTER ASSISTED TOMOGRAPHY; FEMALE; GRAFT NECROSIS; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUNG METASTASIS; METASTASIS; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSICAL EXAMINATION; POSITRON EMISSION TOMOGRAPHY; SEROMA; SHORT COURSE THERAPY; SKIN AUTOGRAFT; SKIN DEFECT; STERNOTOMY; THIGH METASTASIS; ADJUVANT CHEMOTHERAPY; ADJUVANT THERAPY; CHEMICALLY INDUCED DISORDER; COMPASSIONATE USE; FOLLOW UP; LUNG TUMOR; MULTIMODALITY CANCER THERAPY; NECROSIS; PATHOLOGY; PLASTIC SURGERY; POSTOPERATIVE COMPLICATION; REOPERATION; SKIN TRANSPLANTATION; SOFT TISSUE TUMOR; THIGH; VASCULARIZATION;

ADOLESCENT; ANGIOGENESIS INHIBITORS; ANTINEOPLASTIC AGENTS; CHEMOTHERAPY, ADJUVANT; COMBINED MODALITY THERAPY; COMPASSIONATE USE TRIALS; FEMALE; FOLLOW-UP STUDIES; HUMANS; INDOLES; LUNG NEOPLASMS; NECROSIS; POSTOPERATIVE COMPLICATIONS; PYRROLES; RADIOTHERAPY, ADJUVANT; REOPERATION; SARCOMA, ALVEOLAR SOFT PART; SKIN TRANSPLANTATION; SOFT TISSUE NEOPLASMS; SURGICAL FLAPS; THIGH;

EID: 77953143593     PISSN: 03008630     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-0030-1249093     Document Type: Article

References (17)

1. Bui DT, Chunilal A, Mehrara BJ,etal. Outcome of split-thickness skin grafts after external beam radiotherapy. Ann Plast Surg 2004 52 551-556
2. Calaminus G, Schneider DT, Weissbach L, etal. Survival after an antiangiogenetic therapy and surgery in a wide spread growing teratoma originating from a testicular mixed malignant germ cell tumor. Klin Pädiatr 2009 221 136-140
3. Chow LQM, Eckhardt SG. Sunitinib: from rational design to clinical efficacy. J Clin Oncol 2007 25 884-896
4. rd edition. St. Louis Mosby 1995 1067-1093
5. Faivre S, Delbaldo C, Vera K, etal. Safety, pharmacokinetic, and antitumor activity of SU11248, a novel oral multitarget tyrosine kinase inhibitor, in patients with cancer. Clin Oncol 2006 24 25-35
6. Göbel U, Kontny U, Gortner L, etal. Networking in pediatrics and the journal?s view. Klin Pädiatr 2009 221 131-133
7. Kayton ML, Meyers P, Wexler LH, etal. Clinical presentation, treatment, and outcome of alveolar soft part sarcoma in children, adolesents, and young adults. J Pediatr Surg 2006 41 187-193
8. Lacouture ME, Reilly LM, Gerami P, etal. Hand foot skin reaction in cancer patients treated with the multikinase inhibitors sorafenib and sunitinib. Ann Oncol 2008 19 1955-1961
9. Lee WJ, Lee JL, Chang SE, etal. Cutaneous adverse effects in patients treated with the multitargeted kinase inhibitors sorafenib and sunitinib. Br J Dermatol 2009 161 1045-1051
10. Looijenga LHJ. Embryogenesis and metastatic testicular germ cell tumors of adolescents. Klin Pädiatr 2009 221 134-135
11. Machiels JP, Henry S, Zanetta S, etal. Phase II study of sunitinib in recurrent or metastatic squamous cell carcinoma of the head and neck. GORTEC 200601. J Clin Oncol 2010 28 21-28
12. Maris JM, Courtright J, Houghton PJ, etal. Initial testing (stage 1) of sunitinib by the pediatric preclinical testing program. Pediatr Blood Cancer 2008 51 42-48 (Pubitemid 351717388)
13. Portera CA Jr, Ho V, Patel SR, etal. Alveolar soft part sarcoma: clinical course and patterns of mestastasis in 70 patients treated at a single institution. Cancer 2001 91 585-591
14. Reichardt P, Lindner T, Pink D, etal. Chemotherapy in alveolar soft part sarcomas. What do we know? Eur J Cancer 2003 39 1511-1516
15. Roozendaal KJ, de Valk B, ten Velden JJ, etal. Alveolar soft part sarcoma responding to interferon alpha-2b. Br J Cancer 2003 89 243-245
16. Sherman N, Vavilala M, Pollock R, etal. Radiation therapy for alveolar soft part sarcoma. Med Pediatr Oncol 1994 22 380-383
17. Stacchiotti S, Tamborini E, Marrari A, etal. Response to sunitinib malate in advanced alveolar soft part sarcoma. Clin Cancer Res 2009 15 1096-1104