Doxorubicin-loaded QuadraSphere microspheres: Plasma pharmacokinetics and intratumoral drug concentration in an animal model of liver cancer

CardioVascular and Interventional Radiology

Volumn 33, Issue 3, 2010, Pages 576-582

  Lee, Kwang Hun ^a,b   Liapi, Eleni A ^a   Cornell, Curt ^c   Reb, Philippe ^d   Buijs, Manon ^a   Vossen, Josephina A ^a   Ventura, Veronica Prieto ^a   Geschwind, Jean Francois H ^a,e  

^a JOHNS HOPKINS UNIVERSITY   (United States)

^b Yonsei University   (South Korea)

^c BioSphere Medical   (United States)

^d Research and Development Department   (France)

^e JOHNS HOPKINS HOSPITAL   (United States)

Author keywords

Drug eluting microspheres; Hepatic artery chemoembolization; Liver tumor; Superabsorbent microspheres; VX 2 tumor

Indexed keywords

COPOLYMER; DOXORUBICIN; DOXORUBICINOL; MICROSPHERE; POLYVINYL ALCOHOL;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; ARTIFICIAL EMBOLISM; BLAND EMBOLIZATION; CELL DEATH; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG TUMOR LEVEL; IN VITRO STUDY; IN VIVO STUDY; LIVER CANCER; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; SLOW DRUG RELEASE; SUSTAINED DRUG RELEASE; TUMOR CELL; TUMOR NECROSIS;

ACRYLIC RESINS; ANGIOGRAPHY, DIGITAL SUBTRACTION; ANIMALS; CHEMOEMBOLIZATION, THERAPEUTIC; CONTRAST MEDIA; DISEASE MODELS, ANIMAL; DOXORUBICIN; HEPATIC ARTERY; LIVER NEOPLASMS; MALE; MICROSPHERES; POLYMERS; POLYVINYLS; RABBITS;

EID: 77953131722     PISSN: 01741551     EISSN: 1432086X     Source Type: Journal    
DOI: 10.1007/s00270-010-9794-1     Document Type: Article

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