Caffeine, a drug for all seasons

Journal of Hepatology

Volumn 53, Issue 1, 2010, Pages 207-208

  Cronstein, Bruce N ^a  

^a NEW YORK UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Adenosine; Adenosine receptors; Caffeine; Methylxanthines

Indexed keywords

ADENOSINE; CAFFEINE; LIVER ENZYME;

ARTICLE; COHORT ANALYSIS; FATTY LIVER; HEPATITIS C; LIVER CELL; LIVER CIRRHOSIS; LIVER FIBROSIS; NONHUMAN; PRIORITY JOURNAL; PROTECTION;

EID: 77953122426     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2010.02.025     Document Type: Note

References (10)

1. Modi A.A., Feld J.J., Park Y., Kleiner D.E., Everhart J.E., Liang T.J., et al. Increased caffeine consumption is associated with reduced hepatic fibrosis. Hepatology 51 (2010) 201-209
2. Lee K.J., Choi J.H., and Jeong H.G. Hepatoprotective and antioxidant effects of the coffee diterpenes kahweol and cafestol on carbon tetrachloride-induced liver damage in mice. Food Chem Toxicol 45 (2007) 2118-2125
3. Sattin A., and Rall T.W. The effect of adenosine and adenine nucleotides on the cyclic adenosine 3′,5′-phosphate content of guinea pig cerebral cortex slices. Mol Pharmacol 6 (1970) 13-23
4. Fredholm B.B., AP I.J., Jacobson K.A., Klotz K.N., and Linden J. International Union of Pharmacology. XXV. Nomenclature and classification of adenosine receptors. Pharmacol Rev 53 (2001) 527-552
5. Peng Z., Fernandez P., Wilder T., Yee H., Chiriboga L., Chan E.S., et al. Ecto-5′-nucleotidase (CD73) -mediated extracellular adenosine production plays a critical role in hepatic fibrosis. FASEB J 22 (2008) 2263-2272
6. Peng Z., Borea P.A., Wilder T., Yee H., Chiriboga L., Blackburn M.R., et al. Adenosine signaling contributes to ethanol-induced fatty liver in mice. J Clin Invest 119 (2009) 582-594
7. Chan E.S., Montesinos M.C., Fernandez P., Desai A., Delano D.L., Yee H., et al. Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosis. Br J Pharmacol 148 (2006) 1144-1155
8. Gressner O.A., Lahme B., Rehbein K., Siluschek M., Weiskirchen R., and Gressner A.M. Pharmacological application of caffeine inhibits TGF-beta-stimulated connective tissue growth factor expression in hepatocytes via PPARgamma and SMAD2/3-dependent pathways. J Hepatol 49 (2008) 758-767
9. Che J., Chan E.S., and Cronstein B.N. Adenosine A2A receptor occupancy stimulates collagen expression by hepatic stellate cells via pathways involving protein kinase A, Src, and extracellular signal-regulated kinases 1/2 signaling cascade or p38 mitogen-activated protein kinase signaling pathway. Mol Pharmacol 72 (2007) 1626-1636
10. Hashmi A.Z., Hakim W., Kruglov E.A., Watanabe A., Watkins W., Dranoff J.A., et al. Adenosine inhibits cytosolic calcium signals and chemotaxis in hepatic stellate cells. Am J Physiol Gastrointest Liver Physiol 292 (2007) G395-G401