Steroidal alkaloids of Veratrum lobelianum Bernh. and Veratrum nigrum L.

Zeitschrift fur Naturforschung - Section C Journal of Biosciences

Volumn 65, Issue 3-4, 2010, Pages 195-200

  Christov, Veselin ^a   Mikhova, Bozhanka ^a   Ivanova, Antoaneta ^a   Serly, Julianna ^b   Molnar, Joseph ^b   Selenge, Dangaa ^c   Solongo, Amgalan ^c   Kostova, Nadezhda ^a   Gerelt Od, Yadamsuren ^c   Dimitrov, Dimitar ^d  

^a INSTITUTE OF ORGANIC CHEMISTRY   (Bulgaria)

^b UNIVERSITY OF SZEGED   (Hungary)

^c INSTITUTE OF CHEMISTRY AND CHEMICAL TECHNOLOGY   (Mongolia)

^d BULGARIAN ACADEMY OF SCIENCES   (Bulgaria)

Author keywords

Antipro liferative activity; Steroidal alkaloids; Veratrum lobelianum Bernh; Veratrum nigrum L.

Indexed keywords

PHYTOSTEROL; VERANIGRINE; VERATRUM ALKALOID;

ANIMAL; ARTICLE; BULGARIA; CELL DIVISION; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; ISOLATION AND PURIFICATION; LEUKEMIA L 5178 Y; MONGOLIA; MOUSE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PATHOLOGY; TRADITIONAL MEDICINE; VERATRUM;

ANIMALS; BULGARIA; CELL DIVISION; LEUKEMIA L5178; MAGNETIC RESONANCE SPECTROSCOPY; MEDICINE, TRADITIONAL; MICE; MODELS, MOLECULAR; MONGOLIA; PHYTOSTEROLS; VERATRUM; VERATRUM ALKALOIDS;

EID: 77953078238     PISSN: 09395075     EISSN: None     Source Type: Journal    
DOI: 10.1515/znc-2010-3-405     Document Type: Article

References (20)

1. Basterechea M., Preiss A., Coli F., Voigt D., Mola J., and Adam G. (1984), Havanine - a steroidal alkaloid glycoside from Solanum havanense. Phytochemistry 23, 2057-2058.
2. Christov V., Mikhova B., and Selenge D. (2009), (-)-Veranigrine, a new steroidal alkaloid from Veratrum nigrum L. Fitoterapia 80, 25-27.
3. Cong Y., Guo L., Yang J., Li L., Zhou Y., Chen J., and Wang J. (2007), Steroidal alkaloids from Veratrum japonicum with genotoxicity on brain cell DNA of the cerebellum and cerebral cortex in mice. Planta Med. 73, 1588-1591.
4. Cornwell M., Pastan I., and Gottesmann M. (1987), ATP dependent transport of vinblastine in vesicles from human multidrug-resistant cells. J. Biol. Chem. 262, 2166-2170.
5. Gaffi eld W., Wong R. Y., Lundin R. E., and Keeler R. F. (1982), Structure of the steroidal alkaloid muldamine and its deacetyl derivative. Phytochemistry 21, 2397-2400.
6. 13C nuclear magnetic resonances by two-dimensional NMR techniques. Magn. Reson. Chem. 29, 100-112.
7. Huang H., Li H., Tang J., Wang B., Lv Y., Shen Y., and Zhang W. (2008), Steroidal alkaloids from Veratrum schindleri and Veratrum maackii. Biochem. Syst. Ecol. 36, 430-433.
8. Kadota S., Chen S., Li J., Xu G., and Namba T. (1995), A steroidal alkaloid from Veratrum oblongum. Phytochemistry 38, 777-781.
9. Khashimov A., Shakirov R., and Yunusov S. (1970), Structure of veralosine. Khim. Prir. Soedin., 343-346.
10. Khashimov A., Shakirov R., and Yunusov S. (1971), Alkaloids from aboveground parts of Veratrum lobelianum. Structure of veralosinine. Khim. Prir. Soedin., 779-784.
11. Lavie Y., Harel-Orbital T., Gaffi eld W., and Liscovitch M. (2001), Inhibitory effect of steroidal alkaloids on drug transport and multidrug resistance in human cancer cells. Anticancer Res. 21, 1189-1194.
12. Moiseeva G., Shakirov R., Yagudaev M., and Yunusov S. (1976), Circular dichroism of veralosidine and its derivatives. Khim. Prir. Soedin., 623-625.
13. Ripperger H. (1990), 25-Isoetioline from two Solanum species. Phytochemistry 29, 3375-3376.
14. Ripperger H. (1996a), Steroidal alkaloids from roots of Solanum spirale. Phytochemistry 43, 705-707.
15. Ripperger H. (1996b), 22,26-Epiminocholestane alkaloids with unusual (20R)-confi gurations from Solanum species. Phytochemistry 41, 1629-1631.
16. Robert J. (1996), Multidrug resistance and its reversal. General review of fundamental aspects. Ann. Biol. Clin. 54, 3-8.
17. Sayed K., McChesney J., Halim A., Zaghloul A., and Voehler M. (1995), Two steroidal alkaloids from Vera trum viride. Phytochemistry 38, 1547-1550.
18. Tezuka Y., Kikuchi T., Zhao W., Chen J., and Guo Y. (1998a), Two new steroidal alkaloids, 20-isoveratramine and verapatuline, from the roots and rhizomes of Veratrum patulum. J. Nat. Prod. 61, 1078-1081.
19. Tezuka Y., Kikuchi T., Zhao W., Chen J., and Guo Y. (1998b), (+)-Verussurinine, a new steroidal alkaloid from the roots and rhizomes of Veratrum nigrum var. ussuriense and structure revision of (+)-verabenzoamine. J. Nat. Prod. 61, 1397-1399.
20. Zhao W., Tezuka Y., Kikuchi T., Chen J., and Guo Y. (1991), Studies on the constituents of Veratrum plants. II. Constituents of Veratrum nigrum L. var. ussuriense. (1). Structure and 1H- and 13C-nuclear magnetic resonance spectra of a new alkaloid, verussurinine, and related alkaloids. Chem. Pharm. Bull. 39, 549-554.