메뉴 건너뛰기




Volumn 65, Issue 5, 2010, Pages 358-361

Pharmacokinetics of methyl protodioscin in rats

Author keywords

[No Author keywords available]

Indexed keywords

METHYL PROTODIOSCIN; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG;

EID: 77953063647     PISSN: 00317144     EISSN: None     Source Type: Journal    
DOI: 10.1691/ph.2010.9785     Document Type: Article
Times cited : (6)

References (18)
  • 1
    • 42549166064 scopus 로고    scopus 로고
    • Development and validation of a liquid chromatography/tandem mass spectrometry assay for the quantification of methyl protodioscin in rat plasma: Application to a pharmacokinetic study
    • DOI 10.1002/bmc.948
    • Cao X, Yao Z, Chen H, Dai Y, Sun P, Ye W, Yao X (2008) Development and validation of a liquid chromatography/tandem mass spectrometry assay for the quantification of methyl protodioscin in rat plasma: Application to a pharmacokinetic study. Biomed Chromatogr 22: 408-413. (Pubitemid 351577705)
    • (2008) Biomedical Chromatography , vol.22 , Issue.4 , pp. 408-413
    • Cao, X.1    Yao, Z.2    Chen, H.3    Dai, Y.4    Sun, P.5    Ye, W.6    Yao, X.7
  • 4
    • 36248956546 scopus 로고    scopus 로고
    • Method for rapid metabolite profiling of drug candidates in fresh hepatocytes using liquid chromatography coupled with a hybrid quadrupole linear ion trap
    • DOI 10.1002/rcm.3257
    • Gao H, Materne OL, Howe DL, Brummel CL (2007) Method for rapid metabolite profiling of drug candidates in fresh hepatocytes using liquid chromatography coupled with a hybrid quadrupole linear ion trap. Rapid Commun Mass Spectrom 21: 3683-3693. (Pubitemid 350124638)
    • (2007) Rapid Communications in Mass Spectrometry , vol.21 , Issue.22 , pp. 3683-3693
    • Gao, H.1    Materne, O.L.2    Howe, D.L.3    Brummel, C.L.4
  • 5
    • 33745976498 scopus 로고    scopus 로고
    • Microbial metabolism of methyl protodioscin by Aspergillus niger culture-A new androstenedione producing way from steroid
    • DOI 10.1016/j.jsbmb.2006.03.007, PII S0960076006001129
    • He X, Liu B, Wang G, Wang X, Su L, Qu G, Yao X (2006) Microbial metabolism of methyl protodioscin by Aspergillus niger culture-A new androstenedione producingway from steroid. J Steroid Biochem Mol Biol 100: 87-94. (Pubitemid 44067456)
    • (2006) Journal of Steroid Biochemistry and Molecular Biology , vol.100 , Issue.1-3 , pp. 87-94
    • He, X.1    Liu, B.2    Wang, G.3    Wang, X.4    Su, L.5    Qu, G.6    Yao, X.7
  • 6
    • 28844486067 scopus 로고    scopus 로고
    • Bioconversion of methyl protodioscin by Penicillium melinii cells
    • DOI 10.1016/j.enzmictec.2005.06.013, PII S0141022905002711
    • He X, Qiao A, Liu B, Wang X, Wang G, Qu G, Liu R, Yao X (2006) Bioconversion of methyl protodioscin by Penicillium melinii cells. Enzyme Microb Technol 38: 400-406. (Pubitemid 41774507)
    • (2006) Enzyme and Microbial Technology , vol.38 , Issue.3-4 , pp. 400-406
    • He, X.1    Qiao, A.2    Liu, B.3    Wang, X.4    Wang, G.5    Qu, G.6    Liu, R.H.7    Yao, X.8
  • 7
    • 33745967292 scopus 로고    scopus 로고
    • Structural identification of methyl protodioscin metabolites in rats' urine and their antiproliferative activities against human tumor cell lines
    • DOI 10.1016/j.steroids.2006.05.013, PII S0039128X06001292
    • He X, Qiao A, Wang X, Liu B, Jiang M, Su L, Yao X (2006) Structural identification of methyl protodioscin metabolites in rats' urine and their antiproliferative activities against human tumor cell lines. Steroids 71: 828-833. (Pubitemid 44062606)
    • (2006) Steroids , vol.71 , Issue.9 , pp. 828-833
    • He, X.1    Qiao, A.2    Wang, X.3    Liu, B.4    Jiang, M.5    Su, L.6    Yao, X.7
  • 9
    • 0031002622 scopus 로고    scopus 로고
    • Antineoplastic agents; II. Four furostanol glycosides from rhizomes of Dioscorea collettii var. hypoglauca
    • HuK, Dong A, Yao X, Kobayashi H, Iwasaki S (1997) Antineoplastic agents, part 2. Four furostanol glycosides from rhizomes of Dioscorea collettii var. hypoglauca. Planta Med 63: 161-165. (Pubitemid 27196087)
    • (1997) Planta Medica , vol.63 , Issue.2 , pp. 161-165
    • Hu, K.1    Dong, A.2    Yao, X.3    Kobayashi, H.4    Iwasaki, S.5
  • 10
    • 0036244470 scopus 로고    scopus 로고
    • The cytotoxicity of methyl protoneodioscin (NSC-698791) against human cancer cell lines in vitro
    • Hu K, Yao X (2002) The cytotoxicity of methyl protoneodioscin (NSC-698791) against human cancer cell lines in vitro. Anticanc Res 22: 1001-1005. (Pubitemid 34475263)
    • (2002) Anticancer Research , vol.22 , Issue.2 A , pp. 1001-1005
    • Hu, K.1    Yao, X.S.2
  • 11
    • 0041857788 scopus 로고    scopus 로고
    • The cytotoxicity of methyl protodioscin against human cancer cell lines in vitro
    • DOI 10.1081/CNV-120018230
    • Hu K, Yao X (2003) The cytotoxicity of methyl protodioscin against human cancer cell lines in vitro. Cancer Invest 21: 389-393. (Pubitemid 37055671)
    • (2003) Cancer Investigation , vol.21 , Issue.3 , pp. 389-393
    • Hu, K.1    Yao, X.2
  • 12
    • 0026848307 scopus 로고
    • Steroidal saponins from the rhizomes of Smilax menispermoidea
    • Ju Y, Jia Z (1992) Steroidal saponins from the rhizomes of Smilax menispermoidea. Phytochemistry 31: 1349-1351.
    • (1992) Phytochemistry , vol.31 , pp. 1349-1351
    • Ju, Y.1    Jia, Z.2
  • 13
    • 34548639939 scopus 로고    scopus 로고
    • Determination of digoxin in human serum using stable isotope dilution liquid chromatography/electrospray ionization-tandem mass spectrometry
    • DOI 10.1248/bpb.30.1653
    • Kuniko M, Aki H, Yuko Y, Yukari I, Youichi F, Kazutake S (2007) Determination of digoxin in human serum using stable isotope dilution liquid chromatography/electrospray ionization-tandem mass spectrometry. Biol Pharm Bull 30: 1653-1656. (Pubitemid 47403238)
    • (2007) Biological and Pharmaceutical Bulletin , vol.30 , Issue.9 , pp. 1653-1656
    • Mitamura, K.1    Horikawa, A.2    Yamane, Y.3    Ikeda, Y.4    Fujii, Y.5    Shimada, K.6
  • 14
    • 33746176533 scopus 로고    scopus 로고
    • Facile conversion of spirostan saponin into furostan saponin: Synthesis of methyl protodioscin and its 26-thio-analogue
    • DOI 10.1021/ol060594w
    • Li M, Yu B (2006) Facile conversion of spirostan saponin into furostan saponin: synthesis of methyl protodioscin and its 26-thio-analog. Organ Lett 8: 2679-2682. (Pubitemid 44085840)
    • (2006) Organic Letters , vol.8 , Issue.13 , pp. 2679-2682
    • Li, M.1    Yu, B.2
  • 15
    • 19444376774 scopus 로고    scopus 로고
    • Methyl protodioscin induces G2/M arrest and apoptosis in K562 cells with the hyperpolarization of mitochondria
    • Liu M, Yue PYK,Wang Z,Wong RNS (2005) Methyl protodioscin induces G2/M arrest and apoptosis in K562 cells with the hyperpolarization of mitochondria. Cancer Lett 224: 229-241.
    • (2005) Cancer Lett , vol.224 , pp. 229-241
    • Liu, M.1    Yue, P.Y.K.2    Wang, Z.3    Wong, R.N.S.4
  • 17
    • 0020351990 scopus 로고
    • Plant saponins. II. Saponins from the seeds of Costus speciosus
    • Singh SB, Thakur RS (1982) Plant saponins. II. Saponins from the seeds of Costus speciosus. J Nat Prod 45: 667-671.
    • (1982) J Nat Prod , vol.45 , pp. 667-671
    • Singh, S.B.1    Thakur, R.S.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.