Evidence for conformational changes in the yeast deoxyhypusine hydroxylase Lia1 upon iron displacement from its active site

Amino Acids

Volumn 38, Issue 2, 2010, Pages 479-490

  Cano, Veridiana S P ^a   Medrano, Francisco Javier ^b   Park, Myung Hee ^c   Valentini, Sandro R ^a  

^a SÃO PAULO STATE UNIVERSITY UNESP   (Brazil)

^b LABORATÓRIO NACIONAL DE LUZ SÍNCROTRON   (Brazil)

^c NATIONAL INSTITUTE OF DENTAL AND CRANIOFACIAL RESEARCH   (United States)

Author keywords

Deoxyhypusine hydroxylase; eIF5A; Heat repeat containing protein; Hypusine; Iron metalloenzyme; Lia1; Structural analysis

Indexed keywords

DEOXYHYPUSINE HYDROXYLASE; GUANIDINE; HYPUSINE; INITIATION FACTOR 5A; IRON; OXYGENASE; RECOMBINANT ENZYME; UNCLASSIFIED DRUG; MIXED FUNCTION OXIDASE; SACCHAROMYCES CEREVISIAE PROTEIN;

AMINO ACID SYNTHESIS; CONFERENCE PAPER; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME MECHANISM; ENZYME STABILITY; ENZYME SUBSTRATE COMPLEX; GEL ELECTROPHORESIS; GEL FILTRATION; HUMAN VERSUS NONHUMAN DATA; IRON BINDING CAPACITY; MUTATIONAL ANALYSIS; NONHUMAN; PH MEASUREMENT; PRIORITY JOURNAL; PROTEIN FOLDING; STRUCTURE ANALYSIS; X RAY CRYSTALLOGRAPHY; YEAST; ARTICLE; CHEMISTRY; ENZYMOLOGY; GENETICS; KINETICS; METABOLISM; MOLECULAR GENETICS; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN TERTIARY STRUCTURE; SACCHAROMYCES CEREVISIAE;

CATALYTIC DOMAIN; ENZYME STABILITY; IRON; KINETICS; MIXED FUNCTION OXYGENASES; MOLECULAR SEQUENCE DATA; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE, TERTIARY; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS;

EID: 77953060465     PISSN: 09394451     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00726-009-0407-8     Document Type: Conference Paper

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