Prenatal thyroxine treatment disparately affects peripheral and amygdala thyroid hormone levels

Psychoneuroendocrinology

Volumn 35, Issue 6, 2010, Pages 791-797

  Shukla, Pradeep K ^a   Sittig, Laura J ^a   Andrus, Brian M ^a   Schaffer, Daniel J ^a   Batra, Kanchi K ^a   Redei, Eva E ^a  

^a NORTHWESTERN UNIVERSITY   (United States)

Author keywords

Amygdala; Anxiety; Defensive burying; Prenatal; Thyroxine; Wistar Kyoto

Indexed keywords

CORTICOSTERONE; CORTICOTROPIN RELEASING FACTOR; GLUCOCORTICOID RECEPTOR; LIOTHYRONINE; MESSENGER RNA; MONOCARBOXYLATE TRANSPORTER 8; PROTIRELIN; THYROXINE; THYROXINE DEIODINASE;

AMYGDALOID NUCLEUS; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANXIETY; ARTICLE; CONTROLLED STUDY; CORTICOSTERONE BLOOD LEVEL; DEPRESSION; DOSE RESPONSE; DRUG MECHANISM; DRUG MEGADOSE; FEMALE; FORCED SWIMMING TEST; GROOMING; HIPPOCAMPUS; HYPOTHYROIDISM; MALE; NONHUMAN; PRENATAL DRUG EXPOSURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; THYROID FUNCTION; THYROID HORMONE BLOOD LEVEL; THYROID HORMONE METABOLISM; THYROID HORMONE RELEASE; UPREGULATION;

AMYGDALA; ANIMALS; ANXIETY; CORTICOSTERONE; CORTICOTROPIN-RELEASING HORMONE; DEPRESSIVE DISORDER; DISEASE MODELS, ANIMAL; FEMALE; HIPPOCAMPUS; HYPOTHYROIDISM; IODIDE PEROXIDASE; MALE; MONOCARBOXYLIC ACID TRANSPORTERS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; PROTEIN PRECURSORS; RATS; RATS, INBRED WKY; RECEPTORS, GLUCOCORTICOID; THYROTROPIN-RELEASING HORMONE; THYROXINE; TRIIODOTHYRONINE;

EID: 77953027355     PISSN: 03064530     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2009.10.019     Document Type: Article

References (41)

1. Allen Brain Atlas [Internet], 2008. Allen Institute for Brain Science.
2. Aguilar-Valles A., Sanchez E., de Gortari P., Balderas I., Ramirez-Amaya V., Bermudez-Rattoni F., Joseph-Bravo P. Analysis of the stress response in rats trained in the water-maze: differential expression of corticotropin-releasing hormone, CRH-R1, glucocorticoid receptors and brain-derived neurotrophic factor in limbic regions. Neuroendocrinology 2005, 82(5-6):306-319.
3. Ahmadiyeh N., Churchill G.A., Shimomura K., Solberg L.C., Takahashi J.S., Redei E.E. X-linked and lineage-dependent inheritance of coping responses to stress. Mamm. Genome 2003, 14(11):748-757.
4. Ahmadiyeh N., Churchill G.A., Solberg L.C., Baum A.E., Shimomura K., Takahashi J.S., Redei E.E. Lineage is an epigenetic modifier of QTL influencing behavioral coping with stress. Behav. Genet. 2005, 35(2):189-198.
5. Ahmadiyeh N., Slone-Wilcoxon J.L., Takahashi J.S., Redei E.E. Maternal behavior modulates X-linked inheritance of behavioral coping in the defensive burying test. Biol. Psychiatry 2004, 55(11):1069-1074.
6. Auso E., Lavado-Autric R., Cuevas E., Del Rey F.E., Morreale De Escobar G., Berbel P. A moderate and transient deficiency of maternal thyroid function at the beginning of fetal neocorticogenesis alters neuronal migration. Endocrinology 2004, 145(9):4037-4047.
7. Barker D.J., Eriksson J.G., Forsen T., Osmond C. Fetal origins of adult disease: strength of effects and biological basis. Int. J. Epidemiol. 2002, 31(6):1235-1239.
8. Bauer M., Hellweg R., Graf K.J., Baumgartner A. Treatment of refractory depression with high-dose thyroxine. Neuropsychopharmacology 1998, 18(6):444-455.
9. Baum A.E., Solberg L.C., Kopp P., Ahmadiyeh N., Churchill G., Takahashi J.S., Jameson J.L., Redei E.E. Quantitative trait loci associated with elevated thyroid-stimulating hormone in the Wistar Kyoto rat. Endocrinology 2005, 146(2):870-878.
10. Bianco A.C., Salvatore D., Gereben B., Berry M.J., Larsen P.R. Biochemistry, cellular and molecular biology, and physiological roles of the iodothyronine selenodeiodinases. Endocr. Rev. 2002, 23(1):38-89.
11. Campos-Barros A., Meinhold H., Kohler R., Muller F., Eravci M., Baumgartner A. The effects of desipramine on thyroid hormone concentrations in rat brain. Naunyn Schmiedebergs Arch. Pharmacol. 1995, 351(5):469-474.
12. De Boer S.F., Koolhaas J.M. Defensive burying in rodents: ethology, neurobiology and psychopharmacology. Eur. J. Pharmacol. 2003, 463(1-3):145-161.
13. Dumitrescu A.M., Liao X.H., Best T.B., Brockmann K., Refetoff S. A novel syndrome combining thyroid and neurological abnormalities is associated with mutations in a monocarboxylate transporter gene. Am. J. Hum. Genet. 2004, 74(1):168-175.
14. Dunn A.J., Guild A.L., Kramarcy N.R., Ware M.D. Benzodiazepines decrease grooming in response to novelty but not ACTH or beta-endorphin. Pharmacol. Biochem. Behav. 1981, 15(4):605-608.
15. Dussault J.H., Fisher D.A. Thyroid function in mothers of hypothyroid newborns. Obstet. Gynecol. 1999, 93(1):15-20.
16. Friesema E.C., Jansen J., Heuer H., Trajkovic M., Bauer K., Visser T.J. Mechanisms of disease: psychomotor retardation and high T3 levels caused by mutations in monocarboxylate transporter 8. Nat. Clin. Pract. Endocrinol. Metab. 2006, 2(9):512-523.
17. Galton V.A., Wood E.T., St Germain E.A., Withrow C.A., Aldrich G., St Germain G.M., Clark A.S., St Germain D.L. Thyroid hormone homeostasis and action in the type 2 deiodinase-deficient rodent brain during development. Endocrinology 2007, 148(7):3080-3088.
18. Gutierrez-Mariscal M., de Gortari P., Lopez-Rubalcava C., Martinez A., Joseph-Bravo P. Analysis of the anxiolytic-like effect of TRH and the response of amygdalar TRHergic neurons in anxiety. Psychoneuroendocrinology 2008, 33(2):198-213.
19. Haddow J.E., Palomaki G.E., Allan W.C., Williams J.R., Knight G.J., Gagnon J., O'Heir C.E., Mitchell M.L., Hermos R.J., Waisbren S.E., Faix J.D., Klein R.Z. Maternal thyroid deficiency during pregnancy and subsequent neuropsychological development of the child. N. Engl. J. Med. 1999, 341(8):549-555.
20. Heuer H., Maier M.K., Iden S., Mittag J., Friesema E.C., Visser T.J., Bauer K. The monocarboxylate transporter 8 linked to human psychomotor retardation is highly expressed in thyroid hormone-sensitive neuron populations. Endocrinology 2005, 146(4):1701-1706.
21. Kim S.Y., Post R.M., Rosen J.B. Differential regulation of basal and kindling-induced TRH mRNA expression by thyroid hormone in the hypothalamic and limbic structures. Neuroendocrinology 1996, 63(3):297-304.
22. Kolber B.J., Roberts M.S., Howell M.P., Wozniak D.F., Sands M.S., Muglia L.J. Central amygdala glucocorticoid receptor action promotes fear-associated CRH activation and conditioning. Proc. Natl. Acad. Sci. U.S.A. 2008, 105(33):12004-12009.
23. Larisch R., Kley K., Nikolaus S., Sitte W., Franz M., Hautzel H., Tress W., Muller H.W. Depression and anxiety in different thyroid function states. Horm. Metab. Res. 2004, 36(9):650-653.
24. Lein E.S., Hawrylycz M.J., Ao N., Ayres M., Bensinger A., Bernard A., Boe A.F., Boguski M.S., Brockway K.S., Byrnes E.J., Chen L., Chen T.M., Chin M.C., Chong J., Crook B.E., Czaplinska A., Dang C.N., Datta S., Dee N.R., Desaki A.L., Desta T., Diep E., Dolbeare T.A., Donelan M.J., Dong H.W., Dougherty J.G., Duncan B.J., Ebbert A.J., Eichele G., Estin L.K., Faber C., Facer B.A., Fields R., Fischer S.R., Fliss T.P., Frensley C., Gates S.N., Glattfelder K.J., Halverson K.R., Hart M.R., Hohmann J.G., Howell M.P., Jeung D.P., Johnson R.A., Karr P.T., Kawal R., Kidney J.M., Knapik R.H., Kuan C.L., Lake J.H., Laramee A.R., Larsen K.D., Lau C., Lemon T.A., Liang A.J., Liu Y., Luong L.T., Michaels J., Morgan J.J., Morgan R.J., Mortrud M.T., Mosqueda N.F., Ng L.L., Ng R., Orta G.J., Overly C.C., Pak T.H., Parry S.E., Pathak S.D., Pearson O.C., Puchalski R.B., Riley Z.L., Rockett H.R., Rowland S.A., Royall J.J., Ruiz M.J., Sarno N.R., Schaffnit K., Shapovalova N.V., Sivisay T., Slaughterbeck C.R., Smith S.C., Smith K.A., Smith B.I., Sodt A.J., Stewart N.N., Stumpf K.R., Sunkin S.M., Sutram M., Tam A., Teemer C.D., Thaller C., Thompson C.L., Varnam L.R., Visel A., Whitlock R.M., Wohnoutka P.E., Wolkey C.K., Wong V.Y., Wood M., Yaylaoglu M.B., Young R.C., Youngstrom B.L., Yuan X.F., Zhang B., Zwingman T.A., Jones A.R. Genome-wide atlas of gene expression in the adult mouse brain. Nature 2007, 445(7124):168-176.
25. Nosek K., Dennis K., Andrus B.M., Ahmadiyeh N., Baum A.E., Woods L.C., Redei E.E. Context and strain-dependent behavioral response to stress. Behav. Brain Funct. 2008, 4:23.
26. Obregon M.J., Calvo R.M., Del Rey F.E., de Escobar G.M. Ontogenesis of thyroid function and interactions with maternal function. Endocr. Dev. 2007, 10:86-98.
27. Pracyk J.B., Seidler F.J., McCook E.C., Slotkin T.A. Pituitary-thyroid axis reactivity to hyper- and hypothyroidism in the perinatal period: ontogeny of regulation of regulation and long-term programming of responses. J. Dev. Physiol. 1992, 18(3):105-109.
28. Redei E.E., Solberg L.C., Kluczynski J.M., Pare W.P. Paradoxical hormonal and behavioral responses to hypothyroid and hyperthyroid states in the Wistar-Kyoto rat. Neuropsychopharmacology 2001, 24(6):632-639.
29. Sait Gonen M., Kisakol G., Savas Cilli A., Dikbas O., Gungor K., Inal A., Kaya A. Assessment of anxiety in subclinical thyroid disorders. Endocr. J. 2004, 51(3):311-315.
30. Schwartz C.E., Stevenson R.E. The MCT8 thyroid hormone transporter and Allan-Herndon-Dudley syndrome. Best Pract. Res. Clin. Endocrinol. Metab. 2007, 21(2):307-321.
31. Shepard J.D., Myers D.A. Strain differences in anxiety-like behavior: association with corticotropin-releasing factor. Behav. Brain Res. 2008, 186(2):239-245.
32. Shukla P.K., Tang L., Wang Z.J. Phosphorylation of neurogranin, protein kinase C, and Ca2+/calmodulin dependent protein kinase II in opioid tolerance and dependence. Neurosci. Lett. 2006, 404(3):266-269.
33. Solberg L.C., Baum A.E., Ahmadiyeh N., Shimomura K., Li R., Turek F.W., Churchill G.A., Takahashi J.S., Redei E.E. Sex- and lineage-specific inheritance of depression-like behavior in the rat. Mamm. Genome 2004, 15(8):648-662.
34. Treit D., Pinel J.P., Fibiger H.C. Conditioned defensive burying: a new paradigm for the study of anxiolytic agents. Pharmacol. Biochem. Behav. 1981, 15(4):619-626.
35. Tronche F., Kellendonk C., Kretz O., Gass P., Anlag K., Orban P.C., Bock R., Klein R., Schutz G. Disruption of the glucocorticoid receptor gene in the nervous system results in reduced anxiety. Nat. Genet. 1999, 23(1):99-103.
36. Walker P., Courtin F. Transient neonatal hyperthyroidism results in hypothyroidism in the adult rat. Endocrinology 1985, 116(6):2246-2250.
37. Wei Q., Lu X.Y., Liu L., Schafer G., Shieh K.R., Burke S., Robinson T.E., Watson S.J., Seasholtz A.F., Akil H. Glucocorticoid receptor overexpression in forebrain: a mouse model of increased emotional lability. Proc. Natl. Acad. Sci. U.S.A. 2004, 101(32):11851-11856.
38. Wilcoxon J.S., Kuo A.G., Disterhoft J.F., Redei E.E. Behavioral deficits associated with fetal alcohol exposure are reversed by prenatal thyroid hormone treatment: a role for maternal thyroid hormone deficiency in FAE. Mol. Psychiatry 2005, 10(10):961-971.
39. Wilcoxon J.S., Redei E.E. Prenatal programming of adult thyroid function by alcohol and thyroid hormones. Am. J. Physiol. Endocrinol. Metab. 2004, 287(2):E318-E326.
40. Yilmazer-Hanke D.M., Hantsch M., Hanke J., Schulz C., Faber-Zuschratter H., Schwegler H. Neonatal thyroxine treatment: changes in the number of corticotropin-releasing-factor (CRF) and neuropeptide Y (NPY) containing neurons and density of tyrosine hydroxylase positive fibers (TH) in the amygdala correlate with anxiety-related behavior of Wistar rats. Neuroscience 2004, 124(2):283-297.
41. Zoeller R.T., Bigelow C., Rovet J. Lack of a relation between human neonatal thyroxine and pediatric neurobehavioral disorders: neonatal total thyroxine is not a good proxy measure of maternal thyroid hormone insufficiency. Thyroid 2004, 14(3):239-241. author reply 241-233.