NOX activity in brain aging: Exacerbation by high fat diet

Free Radical Biology and Medicine

Volumn 49, Issue 1, 2010, Pages 22-30

  Bruce Keller, Annadora J ^a   White, Christy L ^a   Gupta, Sunita ^a   Knight, Alecia G ^a   Pistell, Paul J ^a   Ingram, Donald K ^a   Morrison, Christopher D ^a   Keller, Jeffrey N ^a  

^a PENNINGTON BIOMEDICAL RESEARCH CENTER   (United States)

Author keywords

Metabolic dysfunction; Neurodegeneration; Obesity; Oxidative stress; Western diet

Indexed keywords

REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; DIFFERENTIATION ANTIGEN; FAT INTAKE;

AGING; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN NERVE CELL; BRAIN REGION; CALORIC INTAKE; CARBONYLATION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBUNIT; EXPERIMENTAL MOUSE; FRONTAL CORTEX; HISTOPATHOLOGY; LIPID DIET; MALE; MICROGLIA; MOUSE; NONHUMAN; OXIDATION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; QUANTITATIVE STUDY; AGE; ANIMAL; BRAIN CORTEX; C57BL MOUSE; DRUG EFFECTS; FAT INTAKE; GLIA; METABOLISM; OXIDATION REDUCTION REACTION; PATHOLOGY; PHYSIOLOGY; PROTEIN CARBONYLATION;

AGE FACTORS; ANIMALS; ANTIGENS, DIFFERENTIATION; CEREBRAL CORTEX; DIETARY FATS; MALE; MICE; MICE, INBRED C57BL; NADPH OXIDASE; NEUROGLIA; OXIDATION-REDUCTION; PROTEIN CARBONYLATION;

MUS;

EID: 77953026364     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2010.03.006     Document Type: Article

References (63)

1. Olufadi R., Byrne C.D. Clinical and laboratory diagnosis of the metabolic syndrome. J. Clin. Pathol. 2008, 61:697-706.
2. Haslam D.W., James W.P. Obesity. Lancet Neurol. 2005, 366:1197-1209.
3. Elias M.F., Elias P.K., Sullivan L.M., Wolf P.A., D'Agostino R.B. Lower cognitive function in the presence of obesity and hypertension: the Framingham Heart Study. Int. J. Obes. Relat. Metab. Disord. 2003, 27:260-268.
4. Elias M.F., Elias P.K., Sullivan L.M., Wolf P.A., D'Agostino R.B. Obesity, diabetes and cognitive deficit: the Framingham Heart Study. Neurobiol. Aging 2005, 26:11-16.
5. Waldstein S.R., Katzel L.I. Interactive relations of central versus total obesity and blood pressure to cognitive function. Int. J. Obes. (Lond.) 2006, 30:201-207.
6. Ward M.A., Carlsson C.M., Trivedi M.A., Sager M.A., Johnson S.C. The effect of body mass index on global brain volume in middle-aged adults: a cross sectional study. BMC Neurol. 2005, 23.
7. Pannacciulli N., Del Parigi A., Chen K., Le D.S., Reiman E.M., Tataranni P.A. Brain abnormalities in human obesity: a voxel-based morphometric study. Neuroimage 2006, 31:1419-1425.
8. Roberts C.K., Sindhu K.K. Oxidative stress and metabolic syndrome. Life Sci. 2009, 84:705-712.
9. Ansari M.A., Roberts K.N., Scheff S.W. Oxidative stress and modification of synaptic proteins in hippocampus after traumatic brain injury. Free Radic. Biol. Med. 2008, 45:443-452.
10. Reddy P.H. Mitochondrial medicine for aging and neurodegenerative diseases. Neuromolecular Med. 2008, 10:291-315.
11. Stadtman E.R., Levine R.L. Free radical-mediated oxidation of free amino acids and amino acid residues in proteins. Amino Acids 2003, 25:207-218.
12. Smith M.A., Perry G., Richey P.L., Sayre L.M., Anderson V.E., Beal M.F., Kowall N. Oxidative damage in Alzheimer's. Nature 1996, 382:120-121.
13. Zhang X., Dong F., Ren J., Driscoll M.J., Culver B. High dietary fat induces NADPH oxidase-associated oxidative stress and inflammation in rat cerebral cortex. Exp. Neurol. 2005, 191:318-325.
14. Souza C.G., Moreira J.D., Siqueira I.R., Pereira A.G., Rieger D.K., Souza D.O., Souza T.M., Portela L.V., Perry M.L. Highly palatable diet consumption increases protein oxidation in rat frontal cortex and anxiety-like behavior. Life Sci. 2007, 81:198-203.
15. Babior B.M. The respiratory burst oxidase and the molecular basis of chronic granulomatous disease. Am. J. Hematol. 1991, 37:263-266.
16. DeLeo F.R., Quinn M.T. Assembly of the phagocyte NADPH oxidase: molecular interaction of oxidase proteins. J. Leukoc. Biol. 1996, 60:677-691.
17. Chinen I., Shimabukuro M., Yamakawa K., Higa N., Matsuzaki T., Noguchi K., Ueda S., Sakanashi M., Takasu N. Vascular lipotoxicity: endothelial dysfunction via fatty-acid-induced reactive oxygen species overproduction in obese Zucker diabetic fatty rats. Endocrinology 2007, 148:160-165.
18. Patel C., Ghanim H., Ravishankar S., Sia C.L., Viswanathan P., Mohanty P., Dandona P. Prolonged reactive oxygen species generation and nuclear factor-kappaB activation after a high-fat, high-carbohydrate meal in the obese. J. Clin. Endocrinol. Metab. 2007, 92:4476-4479.
19. Silver A.E., Beske S.D., Christou D.D., Donato A.J., Moreau K.L., Eskurza I., Gates P.E., Seals D.R. Overweight and obese humans demonstrate increased vascular endothelial NAD(P)H oxidase-p47(phox) expression and evidence of endothelial oxidative stress. Circulation 2007, 115:627-637.
20. Block M.L. NADPH oxidase as a therapeutic target in Alzheimer's disease. BMC Neurosci. 2008, 9(Suppl 2):S8.
21. Shimohama S., Tanino H., Kawakami N., Okamura N., Kodama H., Yamaguchi T., Hayakawa T., Nunomura A., Chiba S., Perry G., Smith M.A., Fujimoto S. Activation of NADPH oxidase in Alzheimer's disease brains. Biochem. Biophys. Res. Commun. 2000, 273:5-9.
22. Lambeth J.D. Nox enzymes, ROS, and chronic disease: an example of antagonistic pleiotropy. Free Radic. Biol. Med. 2007, 43:332-347.
23. Forster M.J., Dubey A., Dawson K.M., Strutts W.A., Lal H., Sohal R.S. Age-related losses of cognitive function and motor skills in mice are associated with oxidized protein damage in brain. Proc. Natl. Acad. Sci. U. S. A. 1996, 93:4765-4769.
24. Keller J.N., Schmitt F.A., Scheff S.W., Ding Q., Chen Q., Butterfield D.A., Markesbery W.R. Evidence of increased oxidative damage in subjects with mild cognitive impairment. Neurology 2005, 64:1152-1156.
25. Noh K.M., Koh J.Y. Induction and activation by zinc of NADPH oxidase in cultured cortical neurons and astrocytes. J. Neurosci. 2000, 20:1-5.
26. Kim M.J., Shin K.S., Chung Y.B., Jung K.W., Cha C.I., Shin D.H. Immunohistochemical study of p47Phox and gp91Phox distributions in rat brain. Brain Res. 2005, 1040:178-186.
27. Kishida K.T., Pao M., Holland S.M., Klann E. NADPH oxidase is required for NMDA receptor-dependent activation of ERK in hippocampal area CA1. J. Neurochem. 2005, 94:299-306.
28. Tejada-Simon M.V., Serrano F., Villasana L.E., Kanterewicz B.I., Wu G.Y., Quinn M.T., Klann E. Synaptic localization of a functional NADPH oxidase in the mouse hippocampus. Mol. Cell. Neurosci. 2005, 29:97-106.
29. Choi J.Y., Jang E.H., Park C.S., Kang J.H. Enhanced susceptibility to 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine neurotoxicity in high-fat diet-induced obesity. Free Radic. Biol. Med. 2005, 38:806-816.
30. Sriram K., Benkovic S.A., Miller D.B., O'Callaghan J.P. Obesity exacerbates chemically induced neurodegeneration. Neuroscience 2002, 115:1335-1346.
31. Vega-Avelaira D., Moss A., Fitzgerald M. Age-related changes in the spinal cord microglial and astrocytic response profile to nerve injury. Brain Behav. Immun. 2007, 21:617-623.
32. Rogers J., Mastroeni D., Leonard B., Joyce J., Grover A. Neuroinflammation in Alzheimer's disease and Parkinson's disease: are microglia pathogenic in either disorder?. Int. Rev. Neurobiol. 2007, 82:235-246.
33. Ling E.A., Ng Y.K., Wu C.H., Kaur C. Microglia: its development and role as a neuropathology sensor. Prog. Brain Res. 2001, 132:61-79.
34. Cagnin A., Brooks D.J., Kennedy A.M., Gunn R.N., Myers R., Turkheimer F.E., Jones T., Banati R.B. In-vivo measurement of activated microglia in dementia. Lancet 2001, 358:461-467.
35. O'Callaghan J.P., Sriram K. Glial fibrillary acidic protein and related glial proteins as biomarkers of neurotoxicity. Expert Opin. Drug Saf. 2005, 4:433-442.
36. Hilton G.D., Stoica B.A., Byrnes K.R., Faden A.I. Roscovitine reduces neuronal loss, glial activation, and neurologic deficits after brain trauma. J. Cereb. Blood Flow Metab. 2008, 28:1845-1859.
37. Lee C.H., Hwang I.K., Lee I.S., Yoo K.Y., Choi J.H., Lee B.H., Won M.H. Differential immunoreactivity of microglial and astrocytic marker protein in the hippocampus of the seizure resistant and sensitive gerbils. J. Vet. Med. Sci. 2008, 70:1405-1409.
38. Zecca L., Wilms H., Geick S., Claasen J.H., Brandenburg L.O., Holzknecht C., Panizza M.L., Zucca F.A., Deuschl G., Sievers J., Lucius R. Human neuromelanin induces neuroinflammation and neurodegeneration in the rat substantia nigra: implications for Parkinson's disease. Acta Neuropathol. 2008, 116:47-55.
39. Park L., Anrather J., Girouard H., Zhou P., Iadecola C. Nox2-derived reactive oxygen species mediate neurovascular dysregulation in the aging mouse brain. J. Cereb. Blood Flow Metab. 2007, 27:1908-1918.
40. Harman D. Aging: a theory based on free radical and radiation chemistry. J. Gerontol. 1956, 11:298-300.
41. Harman D. Free radical involvement in aging. Pathophysiology and therapeutic implications. Drugs Aging 1993, 3:60-80.
42. Markesbery W.R., Lovell M.A. Four-hydroxynonenal, a product of lipid peroxidation, is increased in the brain in Alzheimer's disease. Neurobiol. Aging 1998, 19:33-36.
43. Swerdlow R.H., Khan S.M. A "mitochondrial cascade hypothesis" for sporadic Alzheimer's disease. Med. Hypotheses 2004, 63:8-20.
44. Niikura T., Yamada M., Chiba T., Aiso S., Matsuoka M., Nishimoto I. Characterization of V642I-AbetaPP-induced cytotoxicity in primary neurons. J. Neurosci. Res. 2004, 77:54-62.
45. Lambeth J.D. NOX enzymes and the biology of reactive oxygen. Nat. Rev. Immunol. 2004, 4:181-189.
46. Geiszt M., Leto T.L. The Nox family of NAD(P)H oxidases: host defense and beyond. J. Biol. Chem. 2004, 279:51715-51718.
47. Krause K.H. Tissue distribution and putative physiological function of NOX family NADPH oxidases. Jpn J. Infect. Dis. 2004, 57:S28-S29.
48. Sorce S., Krause K.H. NOX enzymes in the central nervous system: from signaling to disease. Antioxid. Redox Signal. 2009, 11:2481-2504.
49. Bruce-Keller A.J., Keller J.N., Morrison C.D. Obesity and vulnerability of the CNS. Biochim. Biophys. Acta 2009, 1792:395-400.
50. Sena A., Sarliève L.L., Rebel G. Brain myelin of genetically obese mice. J. Neurol. Sci. 1985, 68:233-243.
51. Jagust W. What can imaging reveal about obesity and the brain?. Curr. Alzheimer Res. 2007, 4:135-139.
52. Gazdzinski S., Kornak J., Weiner M.W., Meyerhoff D.J. Body mass index and magnetic resonance markers of brain integrity in adults. Ann. Neurol. 2008, 63:652-657.
53. Winocur G., Greenwood C.E. Studies of the effects of high fat diets on cognitive function in a rat model. Neurobiol. Aging 2005, 26:46-49.
54. White C.L., Pistell P.J., Purpera M.N., Gupta S., Fernandez-Kim S.O., Hise T.L., Keller J.N., Ingram D.K., Morrison C.D., Bruce-Keller A.J. Effects of high fat diet on Morris maze performance, oxidative stress, and inflammation in rats: contributions of maternal diet. Neurobiol. Dis. 2009, 35:3-13.
55. Streit W.J., Miller K.R., Lopes K.O., Njie E. Microglial degeneration in the aging brain-bad news for neurons?. Front. Biosci. 2008, 13:3423-3438.
56. McGeer P.L., McGeer E.G. The role of the immune system in neurodegenerative disorders. Mov. Disord. 1997, 12:855-858.
57. Kishida K.T., Klann E. Sources and targets of reactive oxygen species in synaptic plasticity and memory. Antioxid. Redox Signal. 2007, 9:233-244.
58. Pao M., Wiggs E.A., Anastacio M.M., Hyun J., DeCarlo E.S., Miller J.T., Anderson V.L., Malech H.L., Gallin J.I., Holland S.M. Cognitive function in patients with chronic granulomatous disease: a preliminary report. Psychosomatics 2004, 45:230-234.
59. Kishida K.T., Hoeffer C.A., Hu D., Pao M., Holland S.M., Klann E. Synaptic plasticity deficits and mild memory impairments in mouse models of chronic granulomatous disease. Mol. Cell. Biol. 2006, 26:5908-5920.
60. Knapp L.T., Klann E. Role of reactive oxygen species in hippocampal long-term potentiation: contributory or inhibitory?. J. Neurosci. Res. 2002, 70:1-7.
61. Kamsler A., Segal M. Hydrogen peroxide as a diffusible signal molecule in synaptic plasticity. Mol. Neurobiol. 2004, 29:167-178.
62. Hu D., Serrano F., Oury T.D., Klann E. Aging-dependent alterations in synaptic plasticity and memory in mice that overexpress extracellular superoxide dismutase. J. Neurosci. 2006, 26:3933-3941.
63. Liu R., Liu I.Y., Bi X., Thompson R.F., Doctrow S.R., Malfroy B., Baudry M. Reversal of age-related learning deficits and brain oxidative stress in mice with superoxide dismutase/catalase mimetics. Proc. Natl. Acad. Sci. U.S.A. 2003, 100:8526-8531.