Siphonodictyal B1 from a marine sponge increases intracellular calcium levels comparable to the Ca 2+-ATPase (SERCA) inhibitor thapsigargin

Marine Biotechnology

Volumn 12, Issue 3, 2010, Pages 267-272

  Bickmeyer, Ulf ^a   Grube, Achim ^a   Klings, Karl Walter ^a   Pawlik, Joseph R ^b   Köck, Matthias ^a  

^a ALFRED WEGENER INSTITUTE FOR POLAR AND MARINE RESEARCH   (Germany)

^b UNIVERSITY OF NORTH CAROLINA WILMINGTON   (United States)

Author keywords

Calcium signaling; Fura 2; Marine sponge; PC12; Secondary metabolite; Siphonodictyon coralliphagum; Thapsigargin

Indexed keywords

CALCIUM SIGNALING; CELLULAR TARGETS; CORAL REEF; ENDOPLASMIC RETICULUM; EXTRACELLULAR; INTRACELLULAR CALCIUM LEVELS; MARINE SPONGE; NEUROENDOCRINE CELLS; RYANODINE; SCLERACTINIAN CORALS; SECONDARY METABOLITES; SESQUITERPENES; STRUCTURAL SIMILARITY; TERRESTRIAL PLANTS; THAPSIGARGINS;

CALCIUM CARBONATE; ENZYME ACTIVITY; KETONES; METABOLISM; METABOLITES; PHENOLS; SIGNALING;

CALCIUM;

CALCIUM; ENZYME INHIBITOR; HYDROQUINONE DERIVATIVE; SARCOPLASMIC RETICULUM CALCIUM TRANSPORTING ADENOSINE TRIPHOSPHATASE; SESQUITERPENE; SIPHONODICTYAL B1; THAPSIGARGIN;

BIOEROSION; CALCIUM; CORAL REEF; CYTOLOGY; ENZYME ACTIVITY; INHIBITOR; SECONDARY METABOLITE; SPONGE;

ANIMAL; ARTICLE; CELL STRAIN; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; METABOLISM; RAT; SPONGE (PORIFERA); ANTAGONISTS AND INHIBITORS; PC12 CELL LINE;

ANIMALS; CALCIUM; ENZYME INHIBITORS; HYDROQUINONES; MOLECULAR STRUCTURE; PC12 CELLS; PORIFERA; RATS; SARCOPLASMIC RETICULUM CALCIUM-TRANSPORTING ATPASES; SESQUITERPENES; THAPSIGARGIN;

ANTHOZOA; SCLERACTINIA; SIPHONODICTYON CORALLIPHAGUM; THAPSIA; THAPSIA GARGANICA;

EID: 77953021731     PISSN: 14362228     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10126-009-9206-1     Document Type: Article

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