DNA gyrase and topoisomerase IV are dual targets of zabofloxacin in Streptococcus pneumoniae

International Journal of Antimicrobial Agents

Volumn 36, Issue 1, 2010, Pages 97-98

  Park, Hee Soo ^a   Jung, Sung Ji ^a   Kwak, Jin Hwan ^a   Choi, Dong Rack ^b   Choi, Eung Chil ^c  

^a Handong University   (South Korea)

^b DongWha Pharm Ind Co   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE; ASPARTIC ACID; CIPROFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING); DNA TOPOISOMERASE (ATP HYDROLYSING) A; DNA TOPOISOMERASE (ATP HYDROLYSING) B; DNA TOPOISOMERASE IV; GEMIFLOXACIN; GENOMIC DNA; GLUTAMIC ACID; GLYCINE; LYSINE; MOXIFLOXACIN; PHENYLALANINE; PROTEIN PARC; PROTEIN PARE; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SERINE; SPARFLOXACIN; UNCLASSIFIED DRUG; ZABOFLOXACIN;

AMINO ACID SUBSTITUTION; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; BACTERICIDAL ACTIVITY; CONTROLLED STUDY; GENE MUTATION; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; IN VITRO STUDY; INCUBATION TIME; LETTER; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SEQUENCE ANALYSIS; STREPTOCOCCUS PNEUMONIAE;

AMINO ACID SUBSTITUTION; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; DNA GYRASE; DNA TOPOISOMERASE IV; HUMANS; MICROBIAL SENSITIVITY TESTS; MUTATION, MISSENSE; STREPTOCOCCUS PNEUMONIAE;

EID: 77953020893     PISSN: 09248579     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2010.02.022     Document Type: Letter

References (7)

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