Do opioids affect the ability to drive safely

Journal of Pain and Palliative Care Pharmacotherapy

Volumn 24, Issue 2, 2010, Pages 167-169

  Borgeat, Alain ^a   Eisenberg, Elon ^b  

^a BALGRIST UNIVERSITY HOSPITAL   (Switzerland)

^b NONE

Author keywords

Driving ability; Impairment; Opioid; Safety

Indexed keywords

BUPRENORPHINE; FENTANYL; OPIATE;

ANALGESIA; CANCER PAIN; CAR DRIVING; CHRONIC PAIN; CONFUSION; DIZZINESS; DRIVING ABILITY; DRUG BLOOD LEVEL; DRUG DOSE INCREASE; DRUG EXPOSURE; DRUG SAFETY; DRUG TOLERANCE; HUMAN; LONG TERM CARE; LONG TERM EXPOSURE; MOTOR COORDINATION; NAUSEA; PAIN ASSESSMENT; QUALITY OF LIFE; SEDATION; SHORT SURVEY; SHORT TERM MEMORY; SIDE EFFECT; SINGLE DRUG DOSE; SOCIAL BEHAVIOR; SOMNOLENCE; TRAFFIC SAFETY;

ACCIDENTS, TRAFFIC; ANALGESICS, OPIOID; AUTOMOBILE DRIVING; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; PAIN;

EID: 77953015307     PISSN: 15360288     EISSN: 15360539     Source Type: Journal    
DOI: 10.3109/15360281003799296     Document Type: Short Survey

References (16)

1. Weiler JM, Bloomfeld JR, Woodworth GG, et al. Effects of fexofenadine, diphenhydramine, and alcohol on driving performance. A randomized, placebo-controlled trial in the Iowa driving simulator. Ann Intern Med. 2000;132:354-363.
2. Forrest WH Jr, Brown BW Jr, Brown CR, et al. Dextroamphetamine with morphine for the treatment of postoperative pain. N Engl J Med. 1977;296:712-715.
3. Joo S. Methadone substitution and driver ability: research fndings and conclusions from a discussion of experts. J Traffic Med. 1994;22:101-103.
4. Zacny JP. Should people taking opioids for medical reasons be allowed to work and drive? Addiction. 1996;91:1581-1584.
5. Smith AM. Patients taking stable doses of morphine may drive. BMJ. 1996;312:56-57.
6. Hill JL, Zacny JP. Comparing the subjective, psychomotor, and physiological effects of intravenous hydromorphone and morphine in healthy volunteers. Psychopharmacology (Berl). 2000;152:31-39.
7. Foley KM. The treatment of cancer pain. N Engl J Med. 1985;313:84-95.
8. Bruera E, Macmillan K, Hanson J, et al. The cognitive effects of the administration of narcotic analgesics in patients with cancer pain. Pain. 1989;39:13-16. (Pubitemid 19258904)
9. Dellemijn PL, van Duijn H, Vanneste, JA. Prolonged treatment with transdermal fentanyl in neuropathic pain. J Pain Symptom Manage. 1998;16:220-229.
10. Strumpf M, Köhler A, Zenz M, et al. [Opioids and driving ability]. Schmerz. 1997;11:233-240 [in German].
11. Jamison RN, Schein JR, Vallow S, et al. Neuropsychological effects of long-term opioid use in chronic pain patients. J Pain Symptom Manage. 2003;26:913-921.
12. Sabatowski R, Schwalen S, Rettig K, et al. Driving ability under long term treatment with transdermal fentanyl. J Pain Symptom Manage. 2003;25:38-47.
13. Dagtekin O, Gerbershagen HJ, Wagner W, et al. Assessing cognitive and psychomotor performance under longterm treatment with transdermal buprenorphine in chronic noncancer pain patients. Anesth Analg. 2007;105:1442-1448.
14. Ray WA, Fought RL, Decker MD. Psychoactive drugs and the risk of injurious motor vehicle crashes in elderly drivers. Am J Epidemiol. 1992;136:873-883.
15. Fishbain DA, Cutler RB, Rosomoff HL, et al. Are opioiddependent/tolerant patients impaired in driving-related skills? A structured evidence-based review. J Pain Symptom Manage. 2003;25:559-577.
16. Gaertner J, Elsner F, Radbruch L, et al. [Infuence of changes to daily dose of opioids on aspects of cognitive and psychomotor performance involved in driving]. Schmerz. 2008;22:433-441 [in German].