Management of essential hypertension

British Medical Bulletin

Volumn 94, Issue 1, 2010, Pages 189-199

  Mancia, Giuseppe ^a,b,c   Grassi, Guido ^a,b,c  

^a UNIVERSITY OF MILAN   (Italy)

^b SAN GERARDO HOSPITAL   (Italy)

^c ISTITUTO AUXOLOGICO ITALIANO   (Italy)

Author keywords

Antihypertensive treatment; Blood pressure control; Cardioprotection; Compliance to treatment; Hypertension

Indexed keywords

ACETYLSALICYLIC ACID; ALPHA ADRENERGIC RECEPTOR BLOCKING AGENT; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; CALCIUM ANTAGONIST; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; DIURETIC AGENT; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; RAMIPRIL; TELMISARTAN; THIAZIDE DIURETIC AGENT;

ALCOHOL ABSTINENCE; ANTIHYPERTENSIVE THERAPY; BLOOD PRESSURE REGULATION; CLINICAL TRIAL; DIURETIC THERAPY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG EFFICACY; DRUG MEGADOSE; ESSENTIAL HYPERTENSION; FOOD INTAKE; FRUIT; HUMAN; LIFESTYLE MODIFICATION; LOW DRUG DOSE; MONOTHERAPY; PATIENT COMPLIANCE; PHYSICAL ACTIVITY; PRIORITY JOURNAL; RENAL PROTECTION; REVIEW; SMOKING CESSATION; SODIUM RESTRICTION; UNSPECIFIED SIDE EFFECT; VEGETABLE; WEIGHT CONTROL; CARDIOVASCULAR DISEASES; DISEASE MANAGEMENT; DRUG ADMINISTRATION; DRUG COMBINATION; HYPERTENSION; LIFESTYLE;

ANTIHYPERTENSIVE AGENTS; CARDIOVASCULAR DISEASES; DISEASE MANAGEMENT; DRUG ADMINISTRATION SCHEDULE; DRUG THERAPY, COMBINATION; HUMANS; HYPERTENSION; LIFE STYLE; PATIENT COMPLIANCE;

EID: 77953001539     PISSN: 00071420     EISSN: 14718391     Source Type: Journal    
DOI: 10.1093/bmb/ldq004     Document Type: Review

References (28)

1. Guidelines Committee (2007) 2007 European Society of HT-European Society of Cardiology guidelines for the management of arterial HT. J Hypertens, 25, 1105-1187.
2. Lopez AD, Mathers CD, Ezzati M, Jamison DT, Murray CJ (2006) Global and regional burden of disease and risk factors, 2001: systematic analysis of population health data. Lancet, 367, 1747-1757.
3. Haider AW, Larson MG, Franklin SS, Levy D, Framingham Heart Study (2003) Systolic blood pressure, diastolic blood pressure, and pulse pressure as predictors of risk for congestive heart failure in the Framingham Heart Study. Ann Intern Med, 138, 10-16.
4. Dahlöf B (2007) Prevention of stroke in patients with hypertension. Am J Cardiol, 100, 17J-24J.
5. Collins R, MacMahon S (1994) Blood pressure, antihypertensive drug treatment and the risk of stroke and of coronary heart disease. Br Med Bull, 50, 272-298.
6. Staessen JA, Wang JG, Thijs L (2003) Cardiovascular prevention and blood pressure reduction: a quantitative overview updated until 1 March 2003. J Hypertens, 21, 1055-1076.
7. Mancia G (2007) Blood pressure reduction and cardiovascular outcomes: past, present and future. Am J Cardiol, 100(Suppl), 3J-9J.
8. Blood Pressure Lowering Treatment Trialists' Collaboration (2005) Effects of different blood pressure-lowering regimens on major cardiovascular events in individuals with and without diabetes mellitus. Results of prospectively designed overviews of randomized trials. Arch Intern Med, 165, 1410-1419.
9. Blood Pressure Lowering Treatment Trialists' Collaboration (2008) Effects of different regimens to lower blood pressure on major cardiovascular events in older and younger adults: meta-analysis of randomised trials. Br Med J, 336, 1121-1123.
10. Grassi G, Dell'Oro R, Seravalle G, Foglia G, Quarti Trevano F, Mancia G (2002) Short-and long-term neuroadrenergic effects of moderate dietary sodium restriction in essential HT. Circulation, 106, 1957-1961.
11. Law MR, Wald NJ, Morris JK, Jordan RE (2003) Value of low dose combination treatment with BP lowering drugs: analysis of 354 randomised trials. Br Med J, 326, 1427.
12. Wald DS, Law M, Morris JK, Bestwick JP, Wald NJ (2009) Combination therapy versus monotherapy in reducing blood pressure: meta-analysis on 11,000 participants from 42 trials. Am J Med, 122, 290-300.
13. Elliott WJ (2008) What factors contribute to the inadequate control of elevated blood pressure? J Clin Hypertens, 10(Suppl 1), 20-26.
14. ONTARGET Investigators, Yusuf S, Teo KK, Pogue J et al. (2008) Telmisartan, ramipril, or both in patients at high risk for vascular events. N Engl J Med, 358, 1547-1559.
15. Mancia G, Laurent S, Agabiti-Rosei E et al. (2009) Reappraisal of European guidelines on hypertension management: a European Society of Hypertension (ESH) task force document. J Hypertens, 27, 2121-2158.
16. Grassi G, Mancia G (2009) Implementation of new evidence into hypertension guidelines: the case of the ONTARGET and TRANSCEND trials. J Hypertens, 27(Suppl 2), S40-S44.
17. Mazzaglia G, Ambrosioni E, Alacqua M et al. (2009) Adherence to antihypertensive medications and cardiovascular morbidity among newly diagnosed hypertensive patients. Circulation, 120, 1598-1605.
18. Julius S, Kjeldsen SE, Weber M et al. (2004) Outcomes in hypertensive patients at high CV risk treated with regimens based on valsartan or amlodipine: the VALUE randomized trial. Lancet, 363, 2022-2031.
19. Sega R, Facchetti R, Bombelli M et al. (2005) Prognostic value of ambulatory and home blood pressures compared with office BP in the general population: follow-up results from the Pressioni Arteriose Monitorate e Loro Associazioni (PAMELA) study. Circulation, 111, 1777-1783.
20. Mancia G, Grassi G (2002) Systolic and diastolic blood pressure control in antihypertensive drug trials. J Hypertens, 20, 1461-1464.
21. Volpe M, Tocci G, Trimarco B et al. (2007) Blood pressure control in Italy: results of recent surveys on hypertension. J Hypertens, 25, 1491-1498.
22. Suh DC, Kim CM, Choi IS, Plauschinat CA, Barone JA (2009) Trends in blood pressure control and treatment among type 2 diabetes with comorbid hypertension in the United States: 1988-2004. J Hypertens, 27, 1908-1916.
23. Ostchega Y, Dillon CF, Hughes JP, Carroll M, Yoon S (2007) Trends in hypertension prevalence, awareness, treatment, and control in older U.S. adults: data from the National Health and Nutrition Examination Survey 1988 to 2004. J Am Geriatr Soc, 55, 1056-1065.
24. Antikainen RL, Moltchanov VA, Chukwuma C Sr et al., WHO MONICA Project (2006) Trends in the prevalence, awareness, treatment and control of hypertension: the WHO MONICA Project. Eur J Cardiovasc Prev Rehabil, 13, 13-29.
25. Banegas JR, Segura J, Ruilope LM et al., CLUE Study Group Investigators (2004) Blood pressure control and physician management of hypertension in hospital hypertension units in Spain. Hypertension, 43, 1338-1344.
26. Mancia G, Facchetti R, Bombelli M, Grassi G, Sega R (2006) Long-term risk of mortality associated with selective and combined elevation in office, home, and ambulatory blood pressure. Hypertension, 47, 846-853.
27. Zanchetti A, Grassi G, Mancia G (2009) When should antihypertensive drug treatment be initiated and to what levels should systolic blood pressure be lowered? A critical appraisal. J Hypertens, 27, 923-934.
28. Indian Polycap Study (TIPS), Yusuf S, Pais P, Afzal R et al. (2009) Effects of a polypill (Polycap) on risk factors in middle-aged individuals without cardiovascular disease (TIPS): a phase II, double-blind, randomised trial. Lancet, 373, 1341-1351.