Cumulative incidence of false-positive test results in lung cancer screening: A randomized trial

Annals of Internal Medicine

Volumn 152, Issue 8, 2010, Pages 505-512

  Croswell, Jennifer M ^a,b   Baker, Stuart G ^a   Marcus, Pamela M ^a   Clapp, Jonathan D ^a,c   Kramer, Barnett S ^a,b  

^a NATIONAL CANCER INSTITUTE   (United States)

^b NATIONAL INSTITUTES OF HEALTH   (United States)

^c INFORMATION MANAGEMENT SERVICES INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; AGED; ARTICLE; CANCER SCREENING; CIGARETTE SMOKING; CLINICAL TRIAL; COMPUTER ASSISTED TOMOGRAPHY; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIAGNOSTIC PROCEDURE; FALSE NEGATIVE RESULT; FALSE POSITIVE RESULT; FEMALE; FOLLOW UP; HUMAN; INCIDENCE; INTERMETHOD COMPARISON; INVASIVE PROCEDURE; LUNG CANCER; MAJOR CLINICAL STUDY; MALE; PRIORITY JOURNAL; RADIATION DOSE; RANDOMIZED CONTROLLED TRIAL; RISK ASSESSMENT; THORAX RADIOGRAPHY; EARLY DIAGNOSIS; KAPLAN MEIER METHOD; LABORATORY DIAGNOSIS; LUNG TUMOR; MASS SCREENING; METHODOLOGY; MIDDLE AGED; MULTICENTER STUDY; PATIENT COMPLIANCE; RADIOGRAPHY; STANDARD; UNNECESSARY PROCEDURE;

AGED; EARLY DETECTION OF CANCER; FALSE POSITIVE REACTIONS; FEMALE; HUMANS; KAPLAN-MEIERS ESTIMATE; LUNG NEOPLASMS; MALE; MASS CHEST X-RAY; MASS SCREENING; MIDDLE AGED; PATIENT COMPLIANCE; TOMOGRAPHY, X-RAY COMPUTED; UNNECESSARY PROCEDURES;

EID: 77953001300     PISSN: 00034819     EISSN: 15393704     Source Type: Journal    
DOI: 10.7326/0003-4819-152-8-201004200-00007     Document Type: Article

References (46)

1. Steele MF. Hospitals urge screening in lung cancer detection. New York Times. 4 March 2007. Accessed at www.nytimes.com/2007/03/04/nyregion/ nyregionspecial2/04CTtopic.html on August 19, 2008.
2. Bonnie J. Addario Lung Cancer Foundation. Awareness Campaign Launched in Four Major Cities Takes Aim at Lung Cancer. Accessed at www. lungcancerfoundation.org/projects-and-progress/bus-and-subway-campaign/ on 16 July 2009.
3. Lung Cancer Mortality Reduction Act of 2009, S. 332, 111th Cong. (2009). Accessed at www.govtrack.us/congress/billtext.xpd?bill=s111-332 on 16 July 2009.
4. Baecke E, de Koning HJ, Otto SJ, van Iersel CA, van Klaveren RJ. Limited contamination in the Dutch-Belgian randomized lung cancer screening trial (NELSON). Lung Cancer. 2009. [PMID: 19801174]
5. Czaja R, McFall SL, Warnecke RB, Ford L, Kaluzny AD. Preferences of community physicians for cancer screening guidelines. Ann Intern Med. 1994; 120:602-8. [PMID: 8117000] (Pubitemid 24091603)
6. Black WC. Overdiagnosis: an underrecognized cause of confusion and harm in cancer screening [Editorial]. J Natl Cancer Inst. 2000;92:1280-2. [PMID: 10944539]
7. Marcus PM, Bergstralh EJ, Zweig MH, Harris A, Offord KP, Fontana RS. Extended lung cancer incidence follow-up in the Mayo Lung Project and overdiagnosis. J Natl Cancer Inst. 2006;98:748-56. [PMID: 16757699] (Pubitemid 43983298)
8. Brewer NT, Salz T, Lillie SE. Systematic review: the long-term effects of false-positive mammograms. Ann Intern Med. 2007;146:502-10. [PMID: 17404352] (Pubitemid 351650559)
9. Gilbert FJ, Cordiner CM, Affleck IR, Hood DB, Mathieson D, Walker LG. Breast screening: the psychological sequelae of false-positive recall in women with and without a family history of breast cancer. Eur J Cancer. 1998;34:2010-4. [PMID: 10070302] (Pubitemid 28546933)
10. Taylor KL, Shelby R, Gelmann E, McGuire C. Quality of life and trial adherence among participants in the prostate, lung, colorectal, and ovarian cancer screening trial. J Natl Cancer Inst. 2004;96:1083-94. [PMID: 15265970] (Pubitemid 39172410)
11. Ford ME, Havstad SL, Flickinger L, Johnson CC. Examining the effects of false positive lung cancer screening results on subsequent lung cancer screening adherence. Cancer Epidemiol Biomarkers Prev. 2003;12:28-33. [PMID: 12540500] (Pubitemid 36110154)
12. Gohagan J, Marcus P, Fagerstrom R, Pinsky P, Kramer B, Prorok P; Writing Committee, Lung Screening Study Research Group. Baseline findings of a randomized feasibility trial of lung cancer screening with spiral CT scan vs chest radiograph: the Lung Screening Study of the National Cancer Institute. Chest. 2004;126:114-21. [PMID: 15249451]
13. Gohagan JK, Marcus PM, Fagerstrom RM, Pinsky PF, Kramer BS, Prorok PC, et al; Lung Screening Study Research Group. Final results of the Lung Screening Study, a randomized feasibility study of spiral CT versus chest X-ray screening for lung cancer. Lung Cancer. 2005;47:9-15. [PMID: 15603850]
14. Baker SG, Erwin D, Kramer BS. Estimating the cumulative risk of false positive cancer screenings. BMC Med Res Methodol. 2003;3:11. [PMID: 12841854]
15. Oken MM, Marcus PM, Hu P, Beck TM, Hocking W, Kvale PA, et al; PLCO Project Team. Baseline chest radiograph for lung cancer detection in the randomized Prostate, Lung, Colorectal and Ovarian Cancer Screening Trial. J Natl Cancer Inst. 2005;97:1832-9. [PMID: 16368945]
16. Yau G, Lock M, Rodrigues G. Systematic review of baseline low-dose CT lung cancer screening. Lung Cancer. 2007;58:161-70. [PMID: 17723250] (Pubitemid 47513259)
17. Elmore JG, Barton MB, Moceri VM, Polk S, Arena PJ, Fletcher SW. Ten-year risk of false positive screening mammograms and clinical breast examinations. N Engl J Med. 1998;338:1089-96. [PMID: 9545356] (Pubitemid 28227478)
18. Hofvind S, Thoresen S, Tretli S. The cumulative risk of a false-positive recall in the Norwegian Breast Cancer Screening Program. Cancer. 2004;101:1501-7. [PMID: 15378474] (Pubitemid 39318894)
19. Christiansen CL, Wang F, Barton MB, Kreuter W, Elmore JG, Gelfand AE, et al. Predicting the cumulative risk of false-positive mammograms. J Natl Cancer Inst. 2000;92:1657-66. [PMID: 11036111]
20. Njor SH, Olsen AH, Schwartz W, Vejborg I, Lynge E. Predicting the risk of a false-positive test for women following a mammography screening programme. J Med Screen. 2007;14:94-7. [PMID: 17626709] (Pubitemid 47067764)
21. Croswell JM, Kramer BS, Kreimer AR, Prorok PC, Xu JL, Baker SG, et al. Cumulative incidence of false-positive results in repeated, multimodal cancer screening. Ann Fam Med. 2009;7:212-22. [PMID: 19433838]
22. Swensen SJ, Jett JR, Hartman TE, Midthun DE, Mandrekar SJ, Hillman SL, et al. CT screening for lung cancer: five-year prospective experience. Radiology. 2005;235:259-65. [PMID: 15695622]
23. Jett JR, Midthun DE. Commentary: CT screening for lung cancer - caveat emptor. Oncologist. 2008;13:439-44. [PMID: 18448559]
24. Garg K, Keith RL, Byers T, Kelly K, Kerzner AL, Lynch DA, et al. Randomized controlled trial with low-dose spiral CT for lung cancer screening: feasibility study and preliminary results. Radiology. 2002;225:506-10. [PMID: 12409588] (Pubitemid 35239255)
25. Diederich S, Thomas M, Semik M, Lenzen H, Roos N, Weber A, et al. Screening for early lung cancer with low-dose spiral computed tomography: results of annual follow-up examinations in asymptomatic smokers. Eur Radiol. 2004;14:691-702. [PMID: 14727146]
26. Sone S, Li F, Yang ZG, Honda T, Maruyama Y, Takashima S, et al. Results of three-year mass screening programme for lung cancer using mobile low-dose spiral computed tomography scanner. Br J Cancer. 2001;84:25-32. [PMID: 11139308]
27. Swensen SJ, Jett JR, Hartman TE, Midthun DE, Sloan JA, Sykes AM, et al. Lung cancer screening with CT: Mayo Clinic experience. Radiology. 2003;226: 756-61. [PMID: 12601181]
28. MacRedmond R, McVey G, Lee M, Costello RW, Kenny D, Foley C, et al. Screening for lung cancer using low dose CT scanning: results of 2 year follow up. Thorax. 2006;61:54-6. [PMID: 16396954]
29. Chong S, Lee KS, Chung MJ, Kim TS, Kim H, Kwon OJ, et al. Lung cancer screening with low-dose helical CT in Korea: experiences at the Samsung Medical Center. J Korean Med Sci. 2005;20:402-8. [PMID: 15953860]
30. McWilliams A, Mayo J. Computed tomography-detected noncalcified pulmonary nodules: a review of evidence for significance and management. Proc Am Thorac Soc. 2008;5:900-4. [PMID: 19056713]
31. MacMahon H, Austin JH, Gamsu G, Herold CJ, Jett JR, Naidich DP, et al; Fleischner Society. Guidelines for management of small pulmonary nodules detected on CT scans: a statement from the Fleischner Society [Editorial]. Radiology. 2005;237:395-400. [PMID: 16244247]
32. Blanchon T, Bréchot JM, Grenier PA, Ferretti GR, Lemarié E, Milleron B, et al; Dépiscan Group. Baseline results of the Depiscan study: a French randomized pilot trial of lung cancer screening comparing low dose CT scan (LDCT) and chest X-ray (CXR). Lung Cancer. 2007;58:50-8. [PMID: 17624475]
33. van Klaveren RV, Oudkerk M, Mali W, Scholten E, Nackaerts K, Thunnissen E, et al. Baseline and second round results from the population-based Dutch-Belgian randomized lung cancer screening trial (NELSON) [Abstract]. J Clin Oncol. 2008;26:1508.
34. Wilson DO, Weissfeld JL, Fuhrman CR, Fisher SN, Balogh P, Landreneau RJ, et al. The Pittsburgh Lung Screening Study (PLuSS): outcomes within 3 years of a first computed tomography scan. Am J Respir Crit Care Med. 2008; 178:956-61. [PMID: 18635890]
35. Pastorino U, Bellomi M, Landoni C, De Fiori E, Arnaldi P, Picchio M, et al. Early lung-cancer detection with spiral CT and positron emission tomography in heavy smokers: 2-year results. Lancet. 2003;362:593-7. [PMID: 12944057]
36. Tokarskaya ZB, Scott BR, Zhuntova GV, Okladnikova ND, Belyaeva ZD, Khokhryakov VF, et al. Interaction of radiation and smoking in lung cancer induction among workers at the Mayak nuclear enterprise. Health Phys. 2002; 83:833-46. [PMID: 12467291]
37. Pierce DA, Sharp GB, Mabuchi K. Joint effects of radiation and smoking on lung cancer risk among atomic bomb survivors. Radiat Res. 2003;159:511-20. [PMID: 12643796]
38. Henschke CI, Yankelevitz DF, Libby DM, Pasmantier MW, Smith JP, Miettinen OS; International Early Lung Cancer Action Program Investigators. Survival of patients with stage I lung cancer detected on CT screening. N Engl J Med. 2006;355:1763-71. [PMID: 17065637]
39. Brenner DJ. Radiation risks potentially associated with low-dose CT screening of adult smokers for lung cancer. Radiology. 2004;231:440-5. [PMID: 15128988]
40. Brenner DJ, Hall EJ. Computed tomography - an increasing source of radiation exposure. N Engl J Med. 2007;357:2277-84. [PMID: 18046031]
41. van den Bergh KA, Essink-Bot ML, Bunge EM, Scholten ET, Prokop M, van Iersel CA, et al. Impact of computed tomography screening for lung cancer on participants in a randomized controlled trial (NELSON trial). Cancer. 2008; 113:396-404. [PMID: 18484588]
42. Lafata JE, Simpkins J, Lamerato L, Poisson L, Divine G, Johnson CC. The economic impact of false-positive cancer screens. Cancer Epidemiol Biomarkers Prev. 2004;13:2126-32. [PMID: 15598770]
43. Pinsky PF, Miller A, Kramer BS, Church T, Reding D, Prorok P, et al. Evidence of a healthy volunteer effect in the prostate, lung, colorectal, and ovarian cancer screening trial. Am J Epidemiol. 2007;165:874-81. [PMID: 17244633]
44. Erasmus JJ, Gladish GW, Broemeling L, Sabloff BS, Truong MT, Herbst RS, et al. Interobserver and intraobserver variability in measurement of non-small-cell carcinoma lung lesions: implications for assessment of tumor response. J Clin Oncol. 2003;21:2574-82. [PMID: 12829678] (Pubitemid 46606340)
45. Bogot NR, Kazerooni EA, Kelly AM, Quint LE, Desjardins B, Nan B. Interobserver and intraobserver variability in the assessment of pulmonary nodule size on CT using film and computer display methods. Acad Radiol. 2005;12:948-56. [PMID: 16087090] (Pubitemid 41116411)
46. Gierada DS, Pilgram TK, Ford M, Fagerstrom RM, Church TR, Nath H, et al. Lung cancer: interobserver agreement on interpretation of pulmonary findings at low-dose CT screening. Radiology. 2008;246:265-72. [PMID: 18024436] (Pubitemid 350305052)