Cytotoxicity of calcium phosphate crystals and human-derived nanoparticles: An overlooked link

Circulation Research

Volumn 106, Issue 10, 2010, Pages

  Sommer, Andrei P ^a  

^a UNIVERSITY OF ULM   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM PHOSPHATE; HUMAN DERIVED NANOPARTICLE; NANOPARTICLE; UNCLASSIFIED DRUG;

AORTA ANEURYSM; AORTA VALVE DISEASE; CELL DEATH; CELL LEVEL; CHEMICAL COMPOSITION; CRYSTAL STRUCTURE; CYTOTOXICITY; HUMAN; LETTER; MATERIAL COATING; MOLECULAR SIZE; NANOANALYSIS; NONHUMAN; PRIORITY JOURNAL; SMOOTH MUSCLE FIBER;

AORTIC VALVE; CALCINOSIS; CALCIUM PHOSPHATES; CELL DEATH; HUMANS; MUSCLE, SMOOTH, VASCULAR; NANOPARTICLES;

EID: 77952998563     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.110.221374     Document Type: Letter

References (4)

1. Ewence AE, Bootman M, Roderick HL, Skepper JN, McCarthy G, Epple M, Neumann M, Shanahan CM, Proudfoot D. Calcium phosphate crystals induce cell death in human vascular smooth muscle cells: a potential mechanism in atherosclerotic plaque destabilization. Circ Res. 2008;103: e28-e34.
2. Bratos-Pérez MA, Sánchez PL, García de Cruz S, Villacorta E, Palacios IF, Fernández-Fernández JM, Di Stefano S, Orduña-Domingo A, Carrascal Y, Mota P, Martín-Luengo C, Bermejo J, San Roman JA, Rodríguez-Torres A, Fernández-Avilés F. Grupo AORTICA (Grupo de Estudio de la Este-nosis Aórtica). Association between self-replicating calcifying nanopar-ticles and aortic stenosis: a possible link to valve calcification. Eur Heart J. 2008;29:371-376.
3. Schwartz MK, Lieske JC, Hunter LW, Miller VM. Systemic injection of planktonic forms of mammalian-derived nanoparticles alters arterial response to injury in rabbits. Am J Physiol Heart Circ Physiol. 2009;296: H1434-H1441.
4. Wu CY, Martel J, Young D, Young JD. Fetuin-a/albumin-mineral complexes resembling serum calcium granules and putative nanobacteria: demonstration of a dual inhibition-seeding concept. PLoS One. 2009;4:e8058.