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Volumn 196, Issue 6, 2010, Pages 434-439

Efficacy of atypical v. typical antipsychotics in the treatment of early psychosis: Meta-analysis

Author keywords

[No Author keywords available]

Indexed keywords

AMISULPRIDE; ATYPICAL ANTIPSYCHOTIC AGENT; CHLORPROMAZINE; CLOZAPINE; HALOPERIDOL; NEUROLEPTIC AGENT; OLANZAPINE; QUETIAPINE; RISPERIDONE; SULPIRIDE; ZIPRASIDONE; ZUCLOPENTHIXOL;

EID: 77952994419     PISSN: 00071250     EISSN: 14721465     Source Type: Journal    
DOI: 10.1192/bjp.bp.109.066217     Document Type: Article
Times cited : (128)

References (48)
  • 1
    • 0034598111 scopus 로고    scopus 로고
    • Atypical antipsychotics in the treatment of schizophrenia: Systematic overview and meta-regression analysis
    • Geddes J, Freemantle N, Harrison P, Bebbington P. Atypical antipsychotics in the treatment of schizophrenia: systematic overview and meta-regression analysis. BMJ 2000; 321: 1371-1376
    • (2000) BMJ , vol.321 , pp. 1371-1376
    • Geddes, J.1    Freemantle, N.2    Harrison, P.3    Bebbington, P.4
  • 2
    • 0038582771 scopus 로고    scopus 로고
    • New generation antipsychotics versus low-potency conventional antipsychotics: A systematic review and meta-analysis
    • DOI 10.1016/S0140-6736(03)13306-5
    • Leucht S, Wahlbeck K, Hamann J, Kissling W. New generation antipsychotics versus low-potency conventional antipsychotics: a systematic review and meta-analysis. Lancet 2003; 361: 1581-1589 (Pubitemid 36578993)
    • (2003) Lancet , vol.361 , Issue.9369 , pp. 1581-1589
    • Leucht, S.1    Wahlbeck, K.2    Hamann, J.3    Kissling, W.4
  • 3
    • 0038653525 scopus 로고    scopus 로고
    • A meta-analysis of the efficacy of second-generation antipsychotics
    • Davis JM, Chen N, Glick ID. A meta-analysis of the efficacy of second-generation antipsychotics. Arch Gen Psychiatry 2003; 60: 553-564
    • (2003) Arch Gen Psychiatry , vol.60 , pp. 553-564
    • Davis, J.M.1    Chen, N.2    Glick, I.D.3
  • 4
    • 58049157203 scopus 로고    scopus 로고
    • Second-generation versus first-generation antipsychotic drugs for schizophrenia: A meta-analysis
    • Leucht S, Corves C, Arbter D, Engel RR, Li C, Davis JM. Second-generation versus first-generation antipsychotic drugs for schizophrenia: a meta-analysis. Lancet 2009; 373: 31-41.
    • (2009) Lancet , vol.373 , pp. 31-41
    • Leucht, S.1    Corves, C.2    Arbter, D.3    Engel, R.R.4    Li, C.5    Davis, J.M.6
  • 5
    • 25144456112 scopus 로고    scopus 로고
    • Effectiveness of antipsychotic drugs in patients with chronic schizophrenia
    • Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Investigators.
    • Lieberman JA, Stroup TS, McEvoy JP, Swartz MS, Rosenheck RA, Perkins DO, et al; Clinical Antipsychotic Trials of Intervention Effectiveness (CATIE) Investigators. Effectiveness of antipsychotic drugs in patients with chronic schizophrenia. N Engl J Med 2005; 353: 1209-1223
    • (2005) N Engl J Med , vol.353 , pp. 1209-1223
    • Lieberman, J.A.1    Stroup, T.S.2    McEvoy, J.P.3    Swartz, M.S.4    Rosenheck, R.A.5    Perkins, D.O.6
  • 6
    • 33749321169 scopus 로고    scopus 로고
    • Randomized controlled trial of the effect on quality of life of second- Vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1)
    • DOI 10.1001/archpsyc.63.10.1079
    • Jones PB, Barnes TR, Davies L, Dunn G, Lloyd H, Hayhurst KP, et al. Randomized controlled trial of the effect on Quality of Life of second- vs first-generation antipsychotic drugs in schizophrenia: Cost Utility of the Latest Antipsychotic Drugs in Schizophrenia Study (CUtLASS 1). Arch Gen Psychiatry 2006; 63: 1079-1087 (Pubitemid 44498387)
    • (2006) Archives of General Psychiatry , vol.63 , Issue.10 , pp. 1079-1087
    • Jones, P.B.1    Barnes, T.R.E.2    Davies, L.3    Dunn, G.4    Lloyd, H.5    Hayhurst, K.P.6    Murray, R.M.7    Markwick, A.8    Lewis, S.W.9
  • 7
    • 33846276906 scopus 로고    scopus 로고
    • Cost-effectiveness of second-generation antipsychotics and perphenazine in a randomized trial of treatment for chronic schizophrenia
    • CATIE Study Investigators
    • Rosenheck RA, Leslie DL, Sindelar J, Miller EA, Lin H, Stroup TS, et al; CATIE Study Investigators. Cost-effectiveness of second-generation antipsychotics and perphenazine in a randomized trial of treatment for chronic schizophrenia. Am J Psychiatry 2006; 163: 2080-2089
    • (2006) Am J Psychiatry , vol.163 , pp. 2080-2089
    • Rosenheck, R.A.1    Leslie, D.L.2    Sindelar, J.3    Miller, E.A.4    Lin, H.5    Stroup, T.S.6
  • 8
    • 34447131002 scopus 로고    scopus 로고
    • Cost-effectiveness of first- V. second-generation antipsychotic drugs results from a randomised controlled trial in schizophrenia responding poorly to previous therapy
    • CUtLASS team
    • Davies LM, Lewis S, Jones PB, Barnes TRE, Gaughran F, Hayhurst K, et al; CUtLASS team. Cost-effectiveness of first- v. second-generation antipsychotic drugs: results from a randomised controlled trial in schizophrenia responding poorly to previous therapy. Br J Psychiatry 2007; 191: 14-22.
    • (2007) Br J Psychiatry , vol.191 , pp. 14-22
    • Davies, L.M.1    Lewis, S.2    Jones, P.B.3    Barnes, T.R.E.4    Gaughran, F.5    Hayhurst, K.6
  • 9
    • 53949096962 scopus 로고    scopus 로고
    • Relationship between gross domestic product and duration of untreated psychosis in low- And middle-income countries
    • Large M, Farooq S, Nielssen O, Slade T. Relationship between gross domestic product and duration of untreated psychosis in low- and middle-income countries. Br J Psychiatry 2008; 193: 272-278
    • (2008) Br J Psychiatry , vol.193 , pp. 272-278
    • Large, M.1    Farooq, S.2    Nielssen, O.3    Slade, T.4
  • 10
    • 40449123512 scopus 로고    scopus 로고
    • CATIE and CUtLASS: Can we handle the truth?
    • Lewis S, Lieberman J. CATIE and CUtLASS: can we handle the truth? Br J Psychiatry 2008; 192: 161-163
    • (2008) Br J Psychiatry , vol.192 , pp. 161-163
    • Lewis, S.1    Lieberman, J.2
  • 12
    • 3042664235 scopus 로고    scopus 로고
    • A randomized, controlled comparison of the efficacy and tolerability of low and high doses of haloperidol in the treatment of first-episode psychosis
    • DOI 10.1017/S1461145704004262
    • Oosthuizen P, Emsley R, Jadri Turner H, Keyter N. A randomized, controlled comparison of the efficacy and tolerability of low and high doses of haloperidol in the treatment of first-episode psychosis. Int J Neuropsychopharmacol 2004; 7: 125-131 (Pubitemid 38823279)
    • (2004) International Journal of Neuropsychopharmacology , vol.7 , Issue.2 , pp. 125-131
    • Oosthuizen, P.1    Emsley, R.2    Turner, H.J.3    Keyter, N.4
  • 14
    • 44949234588 scopus 로고    scopus 로고
    • First- V. second-generation antipsychotics and risk for diabetes in schizophrenia: Systematic review and meta-analysis
    • DOI 10.1192/bjp.bp.107.037184
    • Smith M, Hopkins D, Peveler RC, Holt RIG, Woodward M, Ismail K. First- v. second-generation antipsychotics and risk for diabetes in schizophrenia: systematic review and meta-analysis. Br J Psychiatry 2008; 192: 406-411 (Pubitemid 351809892)
    • (2008) British Journal of Psychiatry , vol.192 , Issue.6 , pp. 406-411
    • Smith, M.1    Hopkins, D.2    Peveler, R.C.3    Holt, R.I.G.4    Woodward, M.5    Ismail, K.6
  • 15
    • 69949137687 scopus 로고    scopus 로고
    • Gender differences in premorbid, entry, treatment, and outcome characteristics in a treated epidemiological sample of 661 patients with first episode psychosis
    • Cotton SM, Lambert M, Schimmelmann BG, Foley DL, Morley KI, McGorry PD, Conus P. Gender differences in premorbid, entry, treatment, and outcome characteristics in a treated epidemiological sample of 661 patients with first episode psychosis. Schizophr Res 2009; 114: 17-24.
    • (2009) Schizophr Res , vol.114 , pp. 17-24
    • Cotton, S.M.1    Lambert, M.2    Schimmelmann, B.G.3    Foley, D.L.4    Morley, K.I.5    McGorry, P.D.6    Conus, P.7
  • 17
    • 77952977588 scopus 로고    scopus 로고
    • National Institute for Health and Clinical Excellence
    • National Institute for Health and Clinical Excellence. Schizophrenia. NICE Clinical Guideline 82. NICE, 2009 (http://www.nice.org.uk/nicemedia/pdf/ CG82NICEGuideline.pdf).
    • (2009) Schizophrenia. NICE Clinical Guideline 82
  • 18
    • 85047697275 scopus 로고    scopus 로고
    • Time course for antipsychotic treatment response in first-episode schizophrenia
    • DOI 10.1176/appi.ajp.163.4.743
    • Emsley R, Rabinowitz J, Medori R. Time course for antipsychotic treatment response in first-episode schizophrenia. Am J Psychiatry 2006; 163: 743-745 (Pubitemid 44464590)
    • (2006) American Journal of Psychiatry , vol.163 , Issue.4 , pp. 743-745
    • Emsley, R.1    Rabinowitz, J.2    Medori, R.3
  • 22
    • 40949142200 scopus 로고    scopus 로고
    • Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: An open randomised clinical trial
    • EUFEST study group
    • Kahn RS, Fleischhacker WW, Boter H, Davidson M, Vergouwe Y, Keet IP, et al; EUFEST study group. Effectiveness of antipsychotic drugs in first-episode schizophrenia and schizophreniform disorder: an open randomised clinical trial. Lancet 2008; 371: 1085-1097
    • (2008) Lancet , vol.371 , pp. 1085-1097
    • Kahn, R.S.1    Fleischhacker, W.W.2    Boter, H.3    Davidson, M.4    Vergouwe, Y.5    Keet, I.P.6
  • 23
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ 1997; 315: 629-634 (Pubitemid 27387172)
    • (1997) British Medical Journal , vol.315 , Issue.7109 , pp. 629-634
    • Egger, M.1    Smith, G.D.2    Schneider, M.3    Minder, C.4
  • 24
    • 0033372843 scopus 로고    scopus 로고
    • Risperidone in the treatment of first-episode psychotic patients: A double-blind multicenter study
    • Risperidone Working Group
    • Emsley RA. Risperidone in the treatment of first-episode psychotic patients: a double-blind multicenter study. Risperidone Working Group. Schizophr Bull 1999; 25: 721-729
    • (1999) Schizophr Bull , vol.25 , pp. 721-729
    • Emsley, R.A.1
  • 25
    • 0036838560 scopus 로고    scopus 로고
    • Effects of antipsychotics on prepulse inhibition of the startle response in drug-naïve schizophrenic patients
    • Mackeprang T, Kristiansen KT, Glenthøj BY. Effects of antipsychotics on prepulse inhibition of the startle response in drug-naïve schizophrenic patients. Biol Psychiatry 2002; 52: 863-873
    • (2002) Biol Psychiatry , vol.52 , pp. 863-873
    • Mackeprang, T.1    Kristiansen, K.T.2    Glenthøj, B.Y.3
  • 26
    • 21044457943 scopus 로고    scopus 로고
    • Risperidone and haloperidol in first-episode psychosis: A long-term randomized trial
    • Early Psychosis Global Working Group
    • Schooler N, Rabinowitz J, Davidson M, Emsley R, Harvey PD, Kopala L, et al; Early Psychosis Global Working Group. Risperidone and haloperidol in first-episode psychosis: a long-term randomized trial. Am J Psychiatry 2005; 162: 947-953
    • (2005) Am J Psychiatry , vol.162 , pp. 947-953
    • Schooler, N.1    Rabinowitz, J.2    Davidson, M.3    Emsley, R.4    Harvey, P.D.5    Kopala, L.6
  • 27
    • 33744964843 scopus 로고    scopus 로고
    • Effects of typical and atypical antipsychotics on glucose-insulin homeostasis and lipid metabolism in first-episode schizophrenia
    • Berl
    • Wu RR, Zhao JP, Liu ZN, Zhai JG, Guo XF, Guo WB, et al. Effects of typical and atypical antipsychotics on glucose-insulin homeostasis and lipid metabolism in first-episode schizophrenia. Psychopharmacology (Berl) 2006; 186: 572-578
    • (2006) Psychopharmacology , vol.186 , pp. 572-578
    • Wu, R.R.1    Zhao, J.P.2    Liu, Z.N.3    Zhai, J.G.4    Guo, X.F.5    Guo, W.B.6
  • 30
    • 37049001600 scopus 로고    scopus 로고
    • Maintenance treatment with risperidone or low-dose haloperidol in first-episode schizophrenia: 1-year results of a randomized controlled trial within the German Research Network on Schizophrenia
    • German Study Group on First-Episode Schizophrenia
    • Gaebel W, Riesbeck M, Wölwer W, Klimke A, Eickhoff M, von Wilmsdorff M, et al; German Study Group on First-Episode Schizophrenia. Maintenance treatment with risperidone or low-dose haloperidol in first-episode schizophrenia: 1-year results of a randomized controlled trial within the German Research Network on Schizophrenia. J Clin Psychiatry 2007; 68: 1763-1774
    • (2007) J Clin Psychiatry , vol.68 , pp. 1763-1774
    • Gaebel, W.1    Riesbeck, M.2    Wölwer, W.3    Klimke, A.4    Eickhoff, M.5    Von Wilmsdorff, M.6
  • 32
    • 41849114231 scopus 로고    scopus 로고
    • And schizophrenia - Effect of disease or drug? Results from a randomized, double-blind, controlled prospective study in first-episode schizophrenia
    • Saddichha S, Manjunatha N, Ameen S, Akhtar S.Diabetes and schizophrenia - effect of disease or drug? Results from a randomized, double-blind, controlled prospective study in first-episode schizophrenia. Acta Psychiatr Scand 2008; 117: 342-347
    • (2008) Acta Psychiatr Scand , vol.117 , pp. 342-347
    • Saddichha, S.1    Manjunatha, N.2    Ameen, S.3    Diabetes, A.S.4
  • 33
    • 0037313398 scopus 로고    scopus 로고
    • Subjective experience and D2 receptor occupancy in patients with recent-onset schizophrenia treated with low-dose olanzapine or haloperidol: A randomized double-blind study
    • de Haan L, van Bruggen M, Lavalaye J, Booij J, Dingemans PM, Linszen D. Subjective experience and D2 receptor occupancy in patients with recent-onset schizophrenia treated with low-dose olanzapine or haloperidol: a randomized, double-blind study. Am J Psychiatry 2003; 160: 303-309
    • (2003) Am J Psychiatry , vol.160 , pp. 303-309
    • De Haan, L.1    Van Bruggen, M.2    Lavalaye, J.3    Booij, J.4    Dingemans, P.M.5    Linszen, D.6
  • 34
    • 0042882529 scopus 로고    scopus 로고
    • Comparative efficacy and safety of atypical and conventional antipsychotic drugs in first-episode psychosis: A randomized double-blind trial of olanzapine versus haloperidol
    • HGDH Study Group
    • Lieberman JA, Tollefson G, Tohen M, Green AI, Gur RE, Kahn R, et al; HGDH Study Group. Comparative efficacy and safety of atypical and conventional antipsychotic drugs in first-episode psychosis: a randomized, double-blind trial of olanzapine versus haloperidol. Am J Psychiatry 2003; 160: 1396-1404
    • (2003) Am J Psychiatry , vol.160 , pp. 1396-1404
    • Lieberman, J.A.1    Tollefson, G.2    Tohen, M.3    Green, A.I.4    Gur, R.E.5    Kahn, R.6
  • 35
    • 49549093638 scopus 로고    scopus 로고
    • Proton Magnetic Resonance Spectroscopy during Initial Treatment with Antipsychotic Medication in Schizophrenia
    • Bustillo JR, Rowland LM, Jung R, Brooks WM, Qualls C, Hammond R, et al. Proton Magnetic Resonance Spectroscopy During Initial Treatment With Antipsychotic Medication in Schizophrenia. Neuropsychopharmacology 2008; 33: 2456-2466
    • (2008) Neuropsychopharmacology , vol.33 , pp. 2456-2466
    • Bustillo, J.R.1    Rowland, L.M.2    Jung, R.3    Brooks, W.M.4    Qualls, C.5    Hammond, R.6
  • 36
    • 0037712923 scopus 로고    scopus 로고
    • Atypical and conventional antipsychotic drugs in treatment-naive first-episode schizophrenia: A 52-week randomized trial of clozapine vs chlorpromazine
    • Lieberman JA, Phillips M, Gu H, Stroup S, Zhang P, Kong L, et al. Atypical and conventional antipsychotic drugs in treatment-naive first-episode schizophrenia: a 52-week randomized trial of clozapine vs chlorpromazine. Neuropsychopharmacology 2003; 28: 995-1003.
    • (2003) Neuropsychopharmacology , vol.28 , pp. 995-1003
    • Lieberman, J.A.1    Phillips, M.2    Gu, H.3    Stroup, S.4    Zhang, P.5    Kong, L.6
  • 37
    • 34447502019 scopus 로고    scopus 로고
    • Sex difference in effects of typical and atypical antipsychotics on glucose-insulin homeostasis and lipid metabolism in first-episode schizophrenia
    • Wu RR, Zhao JP, Zhai JG, Guo XF, Guo WB. Sex difference in effects of typical and atypical antipsychotics on glucose-insulin homeostasis and lipid metabolism in first-episode schizophrenia. J Clin Psychopharmacol 2007; 27: 374-379
    • (2007) J Clin Psychopharmacol , vol.27 , pp. 374-379
    • Wu, R.R.1    Zhao, J.P.2    Zhai, J.G.3    Guo, X.F.4    Guo, W.B.5
  • 38
    • 33747398701 scopus 로고    scopus 로고
    • Olanzapine and haloperidol in first episode psychosis: Two-year data
    • HGDH Study Group
    • Green AI, Lieberman JA, Hamer RM, Glick ID, Gur RE, Kahn RS, et al; HGDH Study Group. Olanzapine and haloperidol in first episode psychosis: two-year data. Schizophr Res 2006; 86: 234-243
    • (2006) Schizophr Res , vol.86 , pp. 234-243
    • Green, A.I.1    Lieberman, J.A.2    Hamer, R.M.3    Glick, I.D.4    Gur, R.E.5    Kahn, R.S.6
  • 39
    • 33947287844 scopus 로고    scopus 로고
    • Basal ganglia volumes in drug-naive first-episode schizophrenia patients before and after short-term treatment with either a typical or an atypical antipsychotic drug
    • Glenthøj A, Glenthøj BY, Mackeprang T, Pagsberg AK, Hemmingsen RP, Jernigan TL, et al. Basal ganglia volumes in drug-naive first-episode schizophrenia patients before and after short-term treatment with either a typical or an atypical antipsychotic drug. Psychiatry Res 2007; 154: 199-208.
    • (2007) Psychiatry Res , vol.154 , pp. 199-208
    • Glenthøj, A.1    Glenthøj, B.Y.2    Mackeprang, T.3    Pagsberg, A.K.4    Hemmingsen, R.P.5    Jernigan, T.L.6
  • 42
    • 23744432102 scopus 로고    scopus 로고
    • Effect of switching antipsychotics on antiparkinsonian medication use in schizophrenia: Population-based study
    • DOI 10.1192/bjp.187.2.137
    • Park S, Ross-Degnan D, Adams AS, Sabin J, Kanavos P, Soumerai SB. Effect of switching antipsychotics on antiparkinsonian medication use in schizophrenia: population-based study. Br J Psychiatry 2005; 187: 137-142 (Pubitemid 41139685)
    • (2005) British Journal of Psychiatry , vol.187 , Issue.AUG , pp. 137-142
    • Park, S.1    Ross-Degnan, D.2    Adams, A.S.3    Sabin, J.4    Kanavos, P.5    Soumerai, S.B.6
  • 43
    • 58049189253 scopus 로고    scopus 로고
    • The spurious advance of antipsychotic drug therapy
    • Tyrer P, Kendall T. The spurious advance of antipsychotic drug therapy. Lancet 2009; 373: 4-5.
    • (2009) Lancet , vol.373 , pp. 4-5
    • Tyrer, P.1    Kendall, T.2
  • 44
    • 68849119035 scopus 로고    scopus 로고
    • Neuropsychiatric disorders: The choice of antipsychotics in schizophrenia
    • Margolis RL. Neuropsychiatric disorders: the choice of antipsychotics in schizophrenia. Nat Rev Neurol 2009; 5: 308-310.
    • (2009) Nat Rev Neurol , vol.5 , pp. 308-310
    • Margolis, R.L.1
  • 45
    • 60349086480 scopus 로고    scopus 로고
    • A meta-analysis of head-to-head comparisons of second-generation antipsychotics in the treatment of schizophrenia
    • Leucht S, Komossa K, Rummel-Kluge C, Corves C, Hunger H, Schmid F, et al. A meta-analysis of head-to-head comparisons of second-generation antipsychotics in the treatment of schizophrenia. Am J Psychiatry 2009; 166: 152-163
    • (2009) Am J Psychiatry , vol.166 , pp. 152-163
    • Leucht, S.1    Komossa, K.2    Rummel-Kluge, C.3    Corves, C.4    Hunger, H.5    Schmid, F.6
  • 47
    • 2442467689 scopus 로고    scopus 로고
    • Effects of low-dose risperidone and low-dose zuclopenthixol on cognitive functions in fisrt-episode drug-naive schizophrenic patients
    • Fagerlund B, Mackeprang T, Gade A, Glenthøj BY. Effects of low-dose risperidone and low-dose zuclopenthixol on cognitive functions in first-episode drug-naive schizophrenic patients. CNS Spectr 2004; 9: 364-374 (Pubitemid 38649725)
    • (2004) CNS Spectrums , vol.9 , Issue.5 , pp. 364-374
    • Fagerlund, B.1    Mackeprang, T.2    Gade, A.3    Hemmingsen, R.4    Glenthoj, B.Y.5
  • 48
    • 53049096683 scopus 로고    scopus 로고
    • Short-term treatment with risperidone or haloperidol in first-episode schizophrenia 8-week results of a randomized controlled trial within the German Research Network on Schizophrenia
    • Möller HJ, Riedel M, Jäger M, Wickelmaier F, Maier W, Kühn KU, et al. Short-term treatment with risperidone or haloperidol in first-episode schizophrenia: 8-week results of a randomized controlled trial within the German Research Network on Schizophrenia. Int J Neuropsychopharmacol 2008; 11: 985-987
    • (2008) Int J Neuropsychopharmacol , vol.11 , pp. 985-987
    • Möller, H.J.1    Riedel, M.2    Jäger, M.3    Wickelmaier, F.4    Maier, W.5    Kühn, K.U.6


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