Comparison of distress and pain in infants randomized to groups receiving standard versus multiple immunizations

Infant Behavior and Development

Volumn 33, Issue 3, 2010, Pages 289-296

  Hanson, Denise ^a   Hall, Wendy ^b   Mills, Leslie L ^a   Au, Scholastica ^a   Bhagat, Radhika ^a   Hernandez, Michelle ^a   Slomba, Natalie ^a   Ali, Reem ^b  

^a VANCOUVER COASTAL HEALTH   (Canada)

^b UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Cortisol; Distress; Immunizations; Pain; Simultaneous injections

Indexed keywords

BACTERIAL VACCINE; DIPHTHERIA PERTUSSIS POLIOMYELITIS TETANUS HAEMOPHILUS INFLUENZAE TYPE B VACCINE; HEPATITIS B VACCINE; HYDROCORTISONE; PNEUMOCOCCUS VACCINE; UNCLASSIFIED DRUG; VIRUS VACCINE;

ARTICLE; CHILD BEHAVIOR; CLINICAL TRIAL; CONTROLLED CLINICAL TRIAL; CONTROLLED STUDY; DIPHTHERIA; FEMALE; HAEMOPHILUS INFECTION; HEPATITIS B; HUMAN; HYDROCORTISONE BLOOD LEVEL; IMMUNIZATION; INFANT; MAJOR CLINICAL STUDY; MALE; NOCICEPTION; PAIN; PERTUSSIS; PNEUMOCOCCAL INFECTION; POLIOMYELITIS; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL; TETANUS;

FEMALE; HUMANS; HYDROCORTISONE; IMMUNIZATION; INFANT; INFANT BEHAVIOR; MALE; PAIN; PAIN MEASUREMENT; SALIVA; STRESS, PSYCHOLOGICAL; VACCINATION;

EID: 77952963765     PISSN: 01636383     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.infbeh.2010.03.003     Document Type: Article

References (25)

1. Anand K.J.S., Plotsky P.M. Neonatal pain alters weight gain and pain threshold during development [abstract]. Pediatric Resident 1995, 37:57A.
2. Anand K.J.S., Thrivkraman K.V., Engelmann M., Su Y., Plotsky P.M. Adult rat behavior and stress responses following pain in the neonatal period [abstract]. Pediatric Resident 1995, 37:57A.
3. Andrews K., Fitzgerald M. The cutaneous withdrawal reflex in human neonates: Sensitization, receptive fields, and the effects of contralateral stimulation. Pain 1994, 56:95-101.
4. British Columbia Centre for Disease Control. (2008, November). Communicable disease control: Immunization Program. Retrieved January 20, 2009 from: http://bccdc.org/content.php%3Fitem=193.
5. Bogin F.J., Bernstein B.A., Payton J.S., Schechter N.L., Ristau B.A. Comparison of the pain associated with simultaneous (SIM) vs. sequential (SEQ) immunization injections given at the 9 and 12 month well child visits. Pediatric Resident 2004, 55:210A.
6. Dettling A.C., Gunnar M.R., Donzella B. Cortisol levels of young children in full-day childcare centers: Relations with age and temperament. Psychoneuroendocrinology 1999, 24:519-536.
7. Felt B.T., Mollen E., Diaz S., Renaud E., Zeglis M., Wheatcroft G., et al. Behavioral interventions reduce infant distress at immunization. Archives of Pediatric and Adolescent Medicine 2000, 154:719-724.
8. Fitzgerald M., McIntosh N. Pain and analgesia in the newborn. Archives of Disease in Childhood 1989, 64(4):441-443.
9. Gunnar M.R., Brodersen L., Krueger K., Rigatuso J. Dampening of adrenocortical responses during infancy: Normative changes and individual differences. Child Development 1996, 67:877-889.
10. Gunnar M.R., Broderson L., Nachmias M., Buss K., Rigatuso J. Stress reactivity and attachment security. Developmental Psychobiology 1996, 29(3):191-204.
11. Horn M.I., McCarthy A.M. Children's responses to sequential versus simultaneous immunization injections. Journal of Pediatric Health Care 1999, 13:18-23.
12. Ipp M., Taddio A., Goldbach M., Ben David S., Stevens B., Koren G. Effects of age, gender, and holding on pain response during infant immunization. Canadian Journal Clinical Pharmacology 2004, 11(1):e2-e7.
13. Larson M.C., Prudhomme White B., Cochran A., Donzella B., Gunnar M. Dampening of cortisol response to handling at 3 months in human infants and its relation to sleep, circadian cortisol activity, and behavioral distress. Developmental Psychobiology 1998, 33:327-337.
14. Lawrence J., Alcock D., McGrath P., Kay J., Mac Murray S.B., Dulberg C. The development of a tool to assess neonatal pain. Neonatal Network 1993, 12(6):59-66.
15. Lewis M., Ramsay D.S. Developmental change in infants' response to stress. Child Development 1995, 66:657-670.
16. Lewis M., Ramsay D.S. Stress reactivity and self-recognition. Child Development 1997, 68(4):621-629.
17. Lewis M., Ramsay D.S. Effects of maternal soothing on infant stress response. Child Development 1999, 70(1):11-20.
18. Meyerhoff A.S., Weniger B.G., Jacobs R.J. Economic value to parents of reducing the pain of emotional distress of childhood vaccine injections. The Pediatric Infectious Disease Journal 2001, 20(11):S57-S62.
19. Pasero C., Paice J.A., McCaffery M. Basic mechanisms underlying the causes and effects of pain. Pain: clinical manual 1999, Mosby, St. Louis, MO, pp. 15-34. 2nd ed.
20. American Academy of Pediatrics Red Book - Report on the Committee on Infectious Diseases 2000, American Academy of Pediatrics, IL. 25th ed. L.K. Pickering (Ed.).
21. Pulchalski M., Hummel P. The reality of neonatal pain. Advances in Neonatal Care 2002, 2(5):233-247.
22. Santiago L.B., Jorge S.M., Moreira A.C. Longitudinal evaluation of the development of salivary cortisol circadian rhythm in infancy. Clinical Endocrinology 1996, 44:157-161.
23. Schechter M.L., Zempsky W.T., Cohen L.L., McGrath P.J., McMurtry C.M., Bright M.S. Pain reduction during pediatric immunizations: Evidence-based review and recommendations. Pediatrics 2007, 119(5):e1184-e1198.
24. Watamura S.E., Donzella B., Kertes D.A., Gunnar M.R. Developmental changes in baseline cortisol activity in early childhood: Relations with napping and effortful control. Developmental Psychobiology 2004, 45:125-133.
25. Wilson M.E., Megel M.E., Fredrichs A.M., McLaughlin P. Physiologic and behavioral responses to stress temperament and incidence of infection and atopic disorders in the first year of life: A pilot study. Journal of Pediatric Nursing 2003, 18(4):257-266.