메뉴 건너뛰기




Volumn 10, Issue 6, 2010, Pages 1359-1364

Valganciclovir: Recent progress

Author keywords

Children; Cytomegalovirus; Ganciclovir; Pharmacokinetics; Review; Transplant; Treatment; Valganciclovir

Indexed keywords

GANCICLOVIR; PLACEBO; VALGANCICLOVIR;

EID: 77952919229     PISSN: 16006135     EISSN: 16006143     Source Type: Journal    
DOI: 10.1111/j.1600-6143.2010.03112.x     Document Type: Short Survey
Times cited : (12)

References (30)
  • 2
    • 1942469969 scopus 로고    scopus 로고
    • Efficacy and safety of valganciclovir vs. oral ganciclovir for prevention of cytomegalovirus disease in solid organ transplant recipients
    • Paya C, Humar A, Dominguez E et al. Efficacy and safety of valganciclovir vs. oral ganciclovir for prevention of cytomegalovirus disease in solid organ transplant recipients. Am J Transplant 2004 4 : 611 620.
    • (2004) Am J Transplant , vol.4 , pp. 611-620
    • Paya, C.1    Humar, A.2    Dominguez, E.3
  • 3
    • 0024361608 scopus 로고
    • A randomized, placebo-controlled trial of oral acyclovir for the prevention of cytomegalovirus disease in recipients of renal allografts
    • Balfour J, Henry H, Chace BA, Stapleton JT, Simmons RL, Fryd DS. A randomized, placebo-controlled trial of oral acyclovir for the prevention of cytomegalovirus disease in recipients of renal allografts. N Engl J Med 1989 320 : 1381 1388.
    • (1989) N Engl J Med , vol.320 , pp. 1381-1388
    • Balfour, J.1    Henry, H.2    Chace, B.A.3    Stapleton, J.T.4    Simmons, R.L.5    Fryd, D.S.6
  • 4
    • 6844222818 scopus 로고    scopus 로고
    • Prophylactic oral ganciclovir compared with deferred therapy for control of cytomegalovirus in renal transplant recipients
    • Brennan DC, Garlock KA, Singer GG et al. Prophylactic oral ganciclovir compared with deferred therapy for control of cytomegalovirus in renal transplant recipients. Transplantation 1997 64 : 1843 1846.
    • (1997) Transplantation , vol.64 , pp. 1843-1846
    • Brennan, D.C.1    Garlock, K.A.2    Singer, G.G.3
  • 5
    • 0033551348 scopus 로고    scopus 로고
    • Valacyclovir for the prevention of cytomegalovirus disease after renal transplantation. International Valacyclovir Cytomegalovirus Prophylaxis Transplantation Study Group
    • Lowance D, Neumayer HH, Legendre CM et al. Valacyclovir for the prevention of cytomegalovirus disease after renal transplantation. International Valacyclovir Cytomegalovirus Prophylaxis Transplantation Study Group. N Engl J Med 1999 340 : 1462 1470.
    • (1999) N Engl J Med , vol.340 , pp. 1462-1470
    • Lowance, D.1    Neumayer, H.H.2    Legendre, C.M.3
  • 6
    • 11144358263 scopus 로고    scopus 로고
    • Clinical utility of cytomegalovirus viral load testing for predicting CMV disease in D+R- solid organ transplant recipients
    • Humar A, Paya C, Pescovitz MD et al. Clinical utility of cytomegalovirus viral load testing for predicting CMV disease in D+R- solid organ transplant recipients. Am J Transplant 2004 4 : 644 649.
    • (2004) Am J Transplant , vol.4 , pp. 644-649
    • Humar, A.1    Paya, C.2    Pescovitz, M.D.3
  • 7
    • 33646793647 scopus 로고    scopus 로고
    • 24-week oral ganciclovir prophylaxis in kidney recipients is associated with reduced symptomatic cytomegalovirus disease compared to a 12-week course
    • Doyle AM, Warburton KM, Goral S, Blumberg E, Grossman RA, Bloom RD. 24-week oral ganciclovir prophylaxis in kidney recipients is associated with reduced symptomatic cytomegalovirus disease compared to a 12-week course. Transplantation 2006 81 : 1106 1111.
    • (2006) Transplantation , vol.81 , pp. 1106-1111
    • Doyle, A.M.1    Warburton, K.M.2    Goral, S.3    Blumberg, E.4    Grossman, R.A.5    Bloom, R.D.6
  • 8
    • 4744369713 scopus 로고    scopus 로고
    • Following universal prophylaxis with intravenous ganciclovir and cytomegalovirus immune globulin, valganciclovir is safe and effective for prevention of CMV infection following lung transplantation
    • Zamora MR, Nicolls MR, Hodges TN et al. Following universal prophylaxis with intravenous ganciclovir and cytomegalovirus immune globulin, valganciclovir is safe and effective for prevention of CMV infection following lung transplantation. Am J Transplant 2004 4 : 1635 1642.
    • (2004) Am J Transplant , vol.4 , pp. 1635-1642
    • Zamora, M.R.1    Nicolls, M.R.2    Hodges, T.N.3
  • 9
    • 58049209806 scopus 로고    scopus 로고
    • Prospective follow-up of primary CMV infections after 6 months of valganciclovir prophylaxis in renal transplant recipients
    • Helantera I, Lautenschlager I, Koskinen P. Prospective follow-up of primary CMV infections after 6 months of valganciclovir prophylaxis in renal transplant recipients. Nephrol Dial Transplant 2009 24 : 316 320.
    • (2009) Nephrol Dial Transplant , vol.24 , pp. 316-320
    • Helantera, I.1    Lautenschlager, I.2    Koskinen, P.3
  • 10
    • 84971555413 scopus 로고    scopus 로고
    • The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients
    • In press.
    • Humar A, Lebranchu Y, Vincenti F et al. The efficacy and safety of 200 days valganciclovir cytomegalovirus prophylaxis in high-risk kidney transplant recipients. Am J Transplant In press.
    • Am J Transplant
    • Humar, A.1    Lebranchu, Y.2    Vincenti, F.3
  • 11
    • 65249148542 scopus 로고    scopus 로고
    • Cell-mediated immunity to predict cytomegalovirus disease in high-risk solid organ transplant recipients
    • Kumar D, Chernenko S, Moussa G et al. Cell-mediated immunity to predict cytomegalovirus disease in high-risk solid organ transplant recipients. Am J Transplant 2009 9 : 1214 1222.
    • (2009) Am J Transplant , vol.9 , pp. 1214-1222
    • Kumar, D.1    Chernenko, S.2    Moussa, G.3
  • 12
    • 0033807143 scopus 로고    scopus 로고
    • Valganciclovir results in improved oral absorption of ganciclovir in liver transplant recipients
    • Pescovitz MD, Rabkin J, Merion RM et al. Valganciclovir results in improved oral absorption of ganciclovir in liver transplant recipients. Antimicrob Agents Chemother 2000 44 : 2811 2815.
    • (2000) Antimicrob Agents Chemother , vol.44 , pp. 2811-2815
    • Pescovitz, M.D.1    Rabkin, J.2    Merion, R.M.3
  • 13
    • 2442457528 scopus 로고    scopus 로고
    • Absence of cytomegalovirus-resistance mutations after valganciclovir prophylaxis, in a prospective multicenter study of solid-organ transplant recipients
    • Boivin G, Goyette N, Gilbert C et al. Absence of cytomegalovirus- resistance mutations after valganciclovir prophylaxis, in a prospective multicenter study of solid-organ transplant recipients. J Infect Dis 2004 189 : 1615 1618.
    • (2004) J Infect Dis , vol.189 , pp. 1615-1618
    • Boivin, G.1    Goyette, N.2    Gilbert, C.3
  • 14
    • 21144452373 scopus 로고    scopus 로고
    • Pharmacokinetic profile of ganciclovir after its oral administration and from its prodrug, valganciclovir, in solid organ transplant recipients
    • Wiltshire H, Hirankarn S, Farrell C et al. Pharmacokinetic profile of ganciclovir after its oral administration and from its prodrug, valganciclovir, in solid organ transplant recipients. Clin Pharmacokinet 2005 44 : 495 507.
    • (2005) Clin Pharmacokinet , vol.44 , pp. 495-507
    • Wiltshire, H.1    Hirankarn, S.2    Farrell, C.3
  • 15
    • 20544469697 scopus 로고    scopus 로고
    • Pharmacodynamics of oral ganciclovir and valganciclovir in solid organ transplant recipients
    • Wiltshire H, Paya CV, Pescovitz MD et al. Pharmacodynamics of oral ganciclovir and valganciclovir in solid organ transplant recipients. Transplantation 2005 79 : 1477 1483.
    • (2005) Transplantation , vol.79 , pp. 1477-1483
    • Wiltshire, H.1    Paya, C.V.2    Pescovitz, M.D.3
  • 16
    • 68249152237 scopus 로고    scopus 로고
    • Valganciclovir in adult solid organ transplant recipients: Pharmacokinetic and pharmacodynamic characteristics and clinical interpretation of plasma concentration measurements
    • Perrottet N, Decosterd LA, Meylan P, Pascual M, Biollaz J, Buclin T. Valganciclovir in adult solid organ transplant recipients: Pharmacokinetic and pharmacodynamic characteristics and clinical interpretation of plasma concentration measurements. Clin Pharmacokinet 2009 48 : 399 418.
    • (2009) Clin Pharmacokinet , vol.48 , pp. 399-418
    • Perrottet, N.1    Decosterd, L.A.2    Meylan, P.3    Pascual, M.4    Biollaz, J.5    Buclin, T.6
  • 17
    • 44449178849 scopus 로고    scopus 로고
    • Pharmacokinetics of low and maintenance dose valganciclovir in kidney transplant recipients
    • Chamberlain CE, Penzak SR, Alfaro RM et al. Pharmacokinetics of low and maintenance dose valganciclovir in kidney transplant recipients. Am J Transplant 2008 8 : 1297 1302.
    • (2008) Am J Transplant , vol.8 , pp. 1297-1302
    • Chamberlain, C.E.1    Penzak, S.R.2    Alfaro, R.M.3
  • 18
    • 37049017978 scopus 로고    scopus 로고
    • Experience with low-dose valganciclovir prophylaxis in adult liver transplant recipients
    • Dupuis R, Harris M, Gillis K et al. Experience with low-dose valganciclovir prophylaxis in adult liver transplant recipients. Transplant Proc 2007 39 : 3266 3270.
    • (2007) Transplant Proc , vol.39 , pp. 3266-3270
    • Dupuis, R.1    Harris, M.2    Gillis, K.3
  • 19
    • 0037531594 scopus 로고    scopus 로고
    • Cytomegalovirus disease in high-risk transplant recipients despite ganciclovir or valganciclovir prophylaxis
    • Akalin E, Sehgal V, Ames S et al. Cytomegalovirus disease in high-risk transplant recipients despite ganciclovir or valganciclovir prophylaxis. Am J Transplant 2003 3 : 731 735.
    • (2003) Am J Transplant , vol.3 , pp. 731-735
    • Akalin, E.1    Sehgal, V.2    Ames, S.3
  • 20
    • 2442648883 scopus 로고    scopus 로고
    • Valganciclovir for the prophylaxis of cytomegalovirus disease in pediatric liver transplant recipients
    • Clark BS, Chang IF, Karpen SJ et al. Valganciclovir for the prophylaxis of cytomegalovirus disease in pediatric liver transplant recipients. Transplantation 2004 77 : 1480.
    • (2004) Transplantation , vol.77 , pp. 1480
    • Clark, B.S.1    Chang, I.F.2    Karpen, S.J.3
  • 21
    • 34147102808 scopus 로고    scopus 로고
    • Unexpectedly high inter- and intrapatient variability of ganciclovir levels in children
    • Vethamuthu J, Feber J, Chretien A, Lampe D, Filler G. Unexpectedly high inter- and intrapatient variability of ganciclovir levels in children. Pediatr Transplant 2007 11 : 301 305.
    • (2007) Pediatr Transplant , vol.11 , pp. 301-305
    • Vethamuthu, J.1    Feber, J.2    Chretien, A.3    Lampe, D.4    Filler, G.5
  • 22
    • 67650251911 scopus 로고    scopus 로고
    • Population pharmacokinetics of ganciclovir following administration of valganciclovir in paediatric renal transplant patients
    • Zhao W, Baudouin V, Zhang D, Deschenes G, Guellec CL, Jacqz-Aigrain E. Population pharmacokinetics of ganciclovir following administration of valganciclovir in paediatric renal transplant patients. Clin Pharmacokinet 2009 48 : 321 328.
    • (2009) Clin Pharmacokinet , vol.48 , pp. 321-328
    • Zhao, W.1    Baudouin, V.2    Zhang, D.3    Deschenes, G.4    Guellec, C.L.5    Jacqz-Aigrain, E.6
  • 23
    • 37049016433 scopus 로고    scopus 로고
    • Establishing pharmacokinetic bioequivalence of valganciclovir oral solution versus the tablet formulation
    • Pescovitz MD, Jain A, Robson R, Mulgaonkar S, Freeman R, Bouw MR. Establishing pharmacokinetic bioequivalence of valganciclovir oral solution versus the tablet formulation. Transplant Proc 2007 39 : 3111 3116.
    • (2007) Transplant Proc , vol.39 , pp. 3111-3116
    • Pescovitz, M.D.1    Jain, A.2    Robson, R.3    Mulgaonkar, S.4    Freeman, R.5    Bouw, M.R.6
  • 24
    • 77950510829 scopus 로고    scopus 로고
    • Pharmacokinetics of oral valganciclovir solution and intravenous ganciclovir in pediatric renal and liver transplant recipients
    • in press).
    • Pescovitz MD, Ettenger RB, Strife CF et al. Pharmacokinetics of oral valganciclovir solution and intravenous ganciclovir in pediatric renal and liver transplant recipients. Transpl Infect Dis (in press).
    • Transpl Infect Dis
    • Pescovitz, M.D.1    Ettenger, R.B.2    Strife, C.F.3
  • 25
    • 60749110137 scopus 로고    scopus 로고
    • Valganciclovir dosing according to body surface area and renal function in pediatric solid organ transplant recipients
    • Vaudry W, Ettenger R, Jara P et al. Valganciclovir dosing according to body surface area and renal function in pediatric solid organ transplant recipients. Am J Transplant 2009 9 : 636 643.
    • (2009) Am J Transplant , vol.9 , pp. 636-643
    • Vaudry, W.1    Ettenger, R.2    Jara, P.3
  • 26
    • 34547829434 scopus 로고    scopus 로고
    • Oral valganciclovir is noninferior to intravenous ganciclovir for the treatment of cytomegalovirus disease in solid organ transplant recipients
    • Asberg A, Humar A, Rollag H et al. Oral valganciclovir is noninferior to intravenous ganciclovir for the treatment of cytomegalovirus disease in solid organ transplant recipients. Am J Transplant 2007 7 : 2106 2113.
    • (2007) Am J Transplant , vol.7 , pp. 2106-2113
    • Asberg, A.1    Humar, A.2    Rollag, H.3
  • 27
    • 65249181619 scopus 로고    scopus 로고
    • Long-term outcomes of CMV disease treatment with valganciclovir versus IV ganciclovir in solid organ transplant recipients
    • Asberg A, Humar A, Jardine AG et al. Long-term outcomes of CMV disease treatment with valganciclovir versus IV ganciclovir in solid organ transplant recipients. Am J Transplant 2009 9 : 1205 1213.
    • (2009) Am J Transplant , vol.9 , pp. 1205-1213
    • Asberg, A.1    Humar, A.2    Jardine, A.G.3
  • 28
    • 77953198161 scopus 로고    scopus 로고
    • Sequential treatment of cytomegalovirus infection or disease with a short course of intravenous ganciclovir followed by oral valganciclovir: Efficacy, safety, and pharmacokinetics
    • in press).
    • Caldes A, Gil-Vernet S, Armendariz Y et al. Sequential treatment of cytomegalovirus infection or disease with a short course of intravenous ganciclovir followed by oral valganciclovir: Efficacy, safety, and pharmacokinetics. Transpl Infect Dis 2009 (in press).
    • (2009) Transpl Infect Dis
    • Caldes, A.1    Gil-Vernet, S.2    Armendariz, Y.3
  • 29
    • 65849405940 scopus 로고    scopus 로고
    • Valganciclovir for cytomegalovirus prevention in solid organ transplant patients: An evidence-based reassessment of safety and efficacy
    • Kalil AC, Freifeld AG, Lyden ER, Stoner JA. Valganciclovir for cytomegalovirus prevention in solid organ transplant patients: An evidence-based reassessment of safety and efficacy. PLoS One 2009 4 : e5512.
    • (2009) PLoS One , vol.4 , pp. 5512
    • Kalil, A.C.1    Freifeld, A.G.2    Lyden, E.R.3    Stoner, J.A.4
  • 30
    • 69949089074 scopus 로고    scopus 로고
    • Increased incidence of cytomegalovirus infection in high-risk liver transplant recipients receiving valganciclovir prophylaxis versus ganciclovir prophylaxis
    • Shiley KT, Gasink LB, Barton TD, Pfeiffenberger P, Olthoff KM, Blumberg EA. Increased incidence of cytomegalovirus infection in high-risk liver transplant recipients receiving valganciclovir prophylaxis versus ganciclovir prophylaxis. Liver Transpl 2009 15 : 963 967.
    • (2009) Liver Transpl , vol.15 , pp. 963-967
    • Shiley, K.T.1    Gasink, L.B.2    Barton, T.D.3    Pfeiffenberger, P.4    Olthoff, K.M.5    Blumberg, E.A.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.