The significance of galectin-3 immunohistochemistry, clinical characteristics and liver imaging in differentiating intrahepatic cholangiocarcinoma from adenocarcinoma liver metastasis

Journal of the Medical Association of Thailand

Volumn 93, Issue 5, 2010, Pages 523-528

  Dechaphunkul, Arunee ^a   Kanngurn, Samornmas ^b   Dechsukhum, Chavaboon ^b   Tanutit, Pramot ^b   Khow Ean, Uthai ^b   Sunpaweravong, Patrapim ^a  

^a PRINCE OF SONGKLA UNIVERSITY   (Thailand)

^b PRINCE OF SONGKLA UNIVERSITY   (Thailand)

Author keywords

Adenocarcinoma liver metastasis; Cholangiocarcinoma; Clinical characteristics; Galectin 3; Imaging; Immunohistochemistry

Indexed keywords

CYTOKERATIN 20; CYTOKERATIN 7; GALECTIN 3;

ADENOCARCINOMA; ADULT; APOPTOSIS; BILE DUCT CARCINOMA; BILE DUCT DILATATION; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DIAGNOSTIC IMAGING; DIFFERENTIAL DIAGNOSIS; EXTRACELLULAR MATRIX; FEMALE; HUMAN; HUMAN TISSUE; IMAGE PROCESSING; IMAGE QUALITY; IMMUNOHISTOCHEMISTRY; LIVER METASTASIS; MAJOR CLINICAL STUDY; MALE; PROTEIN EXPRESSION; REVIEW; TUMOR BIOPSY;

ADENOCARCINOMA; ADULT; BILE DUCT NEOPLASMS; BILE DUCTS, INTRAHEPATIC; CHOLANGIOCARCINOMA; FEMALE; GALECTIN 3; HUMANS; IMMUNOHISTOCHEMISTRY; KERATIN-20; KERATIN-7; LIVER; LIVER NEOPLASMS; MALE; MIDDLE AGED; TOMOGRAPHY, X-RAY COMPUTED; TUMOR MARKERS, BIOLOGICAL;

EID: 77952917128     PISSN: 01252208     EISSN: 01252208     Source Type: Journal    
DOI: None     Document Type: Review

References (19)

1. Sasaki A, Kawano K, Aramaki M, Nakashima K, Yoshida T, Kitano S. Immunohistochemical expression of cytokeratins in intrahepatic cholangiocarcinoma and metastatic adenocarcinoma of the liver. J Surg Oncol 1999; 70: 103-8.
2. Anderson CD, Pinson CW, Berlin J, Chari RS. Diagnosis and treatment of cholangiocarcinoma. Oncologist 2004; 9: 43-57.
3. Tot T. Adenocarcinomas metastatic to the liver: the value of cytokeratins 20 and 7 in the search for unknown primary tumors. Cancer 1999; 85: 171-7.
4. Acalovschi M. Cholangiocarcinoma: risk factors, diagnosis and management. Rom J Intern Med 2004; 42: 41-58.
5. Srisomsap C, Sawangareetrakul P, Subhasitanont P, Panichakul T, Keeratichamroen S, Lirdprapamongkol K, et al. Proteomic analysis of cholangiocarcinoma cell line. Proteomics 2004; 4: 1135-44.
6. Inufusa H, Nakamura M, Adachi T, Aga M, Kurimoto M, Nakatani Y, et al. Role of galectin-3 in adenocarcinoma liver metastasis. Int J Oncol 2001; 19: 913-9.
7. Shimonishi T, Miyazaki K, Kono N, Sabit H, Tuneyama K, Harada K, et al. Expression of endogenous galectin-1 and galectin-3 in intrahepatic cholangiocarcinoma. Hum Pathol 2001; 32: 302-10.
8. van den Brule FA, Buicu C, Berchuck A, Bast RC, Deprez M, Liu FT, et al. Expression of the 67-kD laminin receptor, galectin-1, and galectin-3 in advanced human uterine adenocarcinoma. Hum Pathol 1996; 27: 1185-91.
9. Pacis RA, Pilat MJ, Pienta KJ, Wojno K, Raz A, Hogan V, et al. Decreased galectin-3 expression in prostate cancer. Prostate 2000; 44: 118-23.
10. Inohara H, Raz A. Functional evidence that cell surface galectin-3 mediates homotypic cell adhesion. Cancer Res 1995; 55: 3267-71.
11. Kuwabara I, Liu FT. Galectin-3 promotes adhesion of human neutrophils to laminin. J Immunol 1996; 156: 3939-44.
12. Inohara H, Akahani S, Raz A. Galectin-3 stimulates cell proliferation. Exp Cell Res 1998; 245: 294-302.
13. Cooper DN, Massa SM, Barondes SH. Endogenous muscle lectin inhibits myoblast adhesion to laminin. J Cell Biol 1991; 115: 1437-48.
14. Yang RY, Hsu DK, Liu FT. Expression of galectin-3 modulates T-cell growth and apoptosis. Proc Natl Acad Sci U S A 1996; 93: 6737-42.
15. Sanjuan X, Fernandez PL, Castells A, Castronovo V, van den Brule F, Liu FT, et al. Differential expression of galectin 3 and galectin 1 in colorectal cancer progression. Gastroenterology 1997; 113: 1906-15.
16. Skrincosky DM, Allen HJ, Bernacki RJ. Galaptinmediated adhesion of human ovarian carcinoma A121 cells and detection of cellular galaptinbinding glycoproteins. Cancer Res 1993; 53: 2667-75.
17. Xu XC, el Naggar AK, Lotan R. Differential expression of galectin-1 and galectin-3 in thyroid tumors. Potential diagnostic implications. Am J Pathol 1995; 147: 815-22.
18. Lotan R, Ito H, Yasui W, Yokozaki H, Lotan D, Tahara E. Expression of a 31-kDa lactoside-binding lectin in normal human gastric mucosa and in primary and metastatic gastric carcinomas. Int J Cancer 1994; 56: 474-80.
19. Castronovo V, van den Brule FA, Jackers P, Clausse N, Liu FT, Gillet C, et al. Decreased expression of galectin-3 is associated with progression of human breast cancer. J Pathol 1996; 179: 43-8.