Human Prostate Fibroblasts Induce Growth and Confer Castration Resistance and Metastatic Potential in LNCaP Cells

European Urology

Volumn 58, Issue 1, 2010, Pages 162-172

  Thalmann, George N ^a   Rhee, Hong ^b   Sikes, Robert A ^c   Pathak, Sen ^d   Multani, Ashi ^e   Zhau, Haiyen E ^e   Marshall, Fray F ^e   Chung, Leland W K ^e  

^a UNIVERSITY OF BERN   (Switzerland)

^b UNIVERSITY OF VIRGINIA   (United States)

^c UNIVERSITY OF DELAWARE   (United States)

^d UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

^e EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Androgen independence; Animal model; Bone metastasis; LNCaP; Prostate cancer; Prostate fibroblasts; Stromal epithelial Interaction; Transition, peripheral and central zones; Tumor microenvironment

Indexed keywords

ANDROGEN; ANDROSTANOLONE; PROSTATE SPECIFIC ANTIGEN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER GROWTH; CANCER RESISTANCE; CASTRATION; CELL ACTIVITY; CELL INTERACTION; CELL STRAIN LNCAP; CONTROLLED STUDY; EPITHELIUM CELL; FIBROBLAST; GROWTH RATE; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; LYMPH NODE METASTASIS; MALE; METASTASIS POTENTIAL; MOUSE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROSTATE CARCINOMA; PROSTATECTOMY; RAT;

ANIMALS; BONE NEOPLASMS; CARCINOMA; CELL COMMUNICATION; CELL LINE, TUMOR; FIBROBLASTS; HUMANS; LUNG NEOPLASMS; LYMPHATIC METASTASIS; MALE; MICE; MICE, NUDE; ORCHIECTOMY; PROSTATE; PROSTATE-SPECIFIC ANTIGEN; PROSTATECTOMY; PROSTATIC NEOPLASMS; TUMOR MICROENVIRONMENT;

EID: 77952881056     PISSN: 03022838     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eururo.2009.08.026     Document Type: Article

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