The effect of nitric oxide on adherence of P-fimbriated uropathogenic Escherichia coli to human renal epithelial cells

BJU International

Volumn 105, Issue 12, 2010, Pages 1726-1731

  Svensson, Lovisa ^a   Säve, Susanne ^a   Persson, Katarina ^a,b  

^a LINNAEUS UNIVERSITY   (Sweden)

^b ÖREBRO UNIVERSITY   (Sweden)

Author keywords

Adhesion; Nitric oxide; PapG; Renal epithelial cells; Uropathogenic E. coli

Indexed keywords

ADHESIN; BACTERIAL RNA; FIMBRIA PROTEIN; NITRIC OXIDE; NITRIC OXIDE DONOR; PROTEIN PAPG; UNCLASSIFIED DRUG;

ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTERIAL STRAIN; BACTERIUM ADHERENCE; CELL AGGLUTINATION; CONTROLLED STUDY; EPITHELIUM CELL; ERYTHROCYTE; GENE EXPRESSION; HUMAN; HUMAN CELL; KIDNEY EPITHELIUM; NONHUMAN; PAPG GENE; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA EXTRACTION; URINE CULTURE; UROPATHOGENIC ESCHERICHIA COLI; WILD TYPE;

BACTERIAL ADHESION; CELL LINE; ESCHERICHIA COLI INFECTIONS; FIMBRIAE, BACTERIAL; HUMANS; KIDNEY; NITRIC OXIDE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; URINARY TRACT INFECTIONS; UROPATHOGENIC ESCHERICHIA COLI;

EID: 77952862001     PISSN: 14644096     EISSN: 1464410X     Source Type: Journal    
DOI: 10.1111/j.1464-410X.2009.08986.x     Document Type: Article

References (30)

1. Saemann MD, Horl WH, Weichhart T. Uncovering host defences in the urinary tract: cathelicidin and beyond. Nephrol Dial Transplant 2007 22 : 347 349
2. Wright KJ, Hultgren SJ. Sticky fibers and uropathogenesis: bacterial adhesins in the urinary tract. Future Microbiol 2006 1 : 75 87
3. Wullt B. The role of P fimbriae for Escherichia coli establishment and mucosal inflammation in the human urinary tract. Int J Antimicrob Agents 2003 21 : 605 621
4. Tseng CC, Huang JJ, Wang MC et al. PapG II adhesin in the establishment and persistence of Escherichia coli infection in mouse kidneys. Kidney Int 2007 71 : 764 770
5. Lane MC, Mobley HL. Role of P-fimbrial-mediated adherence in pyelonephritis and persistence of uropathogenic Escherichia coli (UPEC) in the mammalian kidney. Kidney Int 2007 72 : 19 25
6. Soto GE, Hultgren SJ. Bacterial adhesins: common themes and variations in architecture and assembly. J Bacteriol 1999 181 : 1059 1071
7. Karr JF, Nowicki B, Truong LD, Hull RA, Hull SI. Purified P fimbriae from two cloned gene clusters of a single pyelonephritogenic strain adhere to unique structures in the human kidney. Infect Immun 1989 57 : 3594 3600
8. Fang FC. Antimicrobial reactive oxygen and nitrogen species: concepts and controversies. Nat Rev Microbiol 2004 2 : 820 832
9. Lundberg JO, Ehren I, Jansson O et al. Elevated nitric oxide in the urinary bladder in infectious and noninfectious cystitis. Urology 1996 48 : 700 702
10. Poljakovic M, Svensson ML, Svanborg C, Johansson K, Larsson B, Persson K. Escherichia coli-induced inducible nitric oxide synthase and cyclooxygenase expression in the mouse bladder and kidney. Kidney Int 2001 59 : 893 904
11. Wheeler MA, Smith SD, Garcia-Cardena G, Nathan CF, Weiss RM, Sessa WC. Bacterial infection induces nitric oxide synthase in human neutrophils. J Clin Invest 1997 99 : 110 116
12. Elgavish A, Robert B, Lloyd K, Reed R. Nitric oxide mediates the action of lipoteichoic acid on the function of human urothelial cells. J Cell Physiol 1996 169 : 66 77
13. Glynne PA, Picot J, Evans TJ. Coexpressed nitric oxide synthase and apical beta(1) integrins influence tubule cell adhesion after cytokine-induced injury. J Am Soc Nephrol 2001 12 : 2370 2383
14. Kabore AF, Denis M, Bergeron MG. Association of nitric oxide production by kidney proximal tubular cells in response to lipopolysaccharide and cytokines with cellular damage. Antimicrob Agents Chemother 1997 41 : 557 562
15. Svensson L, Marklund BI, Poljakovic M, Persson K. Uropathogenic Escherichia coli and tolerance to nitric oxide: the role of flavohemoglobin. J Urol 2006 175 : 749 753
16. Bower JM, Mulvey MA. Polyamine-mediated resistance of uropathogenic Escherichia coli to nitrosative stress. J Bacteriol 2006 188 : 928 933
17. Darling KE, Evans TJ. Effects of nitric oxide on Pseudomonas aeruginosa infection of epithelial cells from a human respiratory cell line derived from a patient with cystic fibrosis. Infect Immun 2003 71 : 2341 2349
18. Vallance BA, Deng W, De Grado M, Chan C, Jacobson K, Finlay BB. Modulation of inducible nitric oxide synthase expression by the attaching and effacing bacterial pathogen citrobacter rodentium in infected mice. Infect Immun 2002 70 : 6424 6435
19. Maresca M, Miller D, Quitard S, Dean P, Kenny B. Enteropathogenic Escherichia coli (EPEC) effector-mediated suppression of antimicrobial nitric oxide production in a small intestinal epithelial model system. Cell Microbiol 2005 7 : 1749 1762
20. Svensson M, Frendeus B, Butters T, Platt F, Dwek R, Svanborg C. Glycolipid depletion in antimicrobial therapy. Mol Microbiol 2003 47 : 453 461
21. Keefer LK, Nims RW, Davies KM, Wink DA. 'NONOates' (1-substituted diazen-1-ium-1,2-diolates) as nitric oxide donors: convenient nitric oxide dosage forms. Methods Enzymol 1996 268 : 281 293
22. Svensson M, Lindstedt R, Radin NS, Svanborg C. Epithelial glucosphingolipid expression as a determinant of bacterial adherence and cytokine production. Infect Immun 1994 62 : 4404 4410
23. Nowicki B, Rhen M, Vaisanen- Rhen V, Pere A, Korhonen TK. Immunofluorescence study of fimbrial phase variation in Escherichia coli KS71. J Bacteriol 1984 160 : 691 695
24. Holden NJ, Totsika M, Mahler E et al. Demonstration of regulatory cross-talk between P fimbriae and type 1 fimbriae in uropathogenic Escherichia coli. Microbiology 2006 152 : 1143 1153
25. Xia Y, Gally D, Forsman-Semb K, Uhlin BE. Regulatory cross-talk between adhesin operons in Escherichia coli: inhibition of type 1 fimbriae expression by the PapB protein. EMBO J 2000 19 : 1450 1457
26. Flatley J, Barrett J, Pullan ST, Hughes MN, Green J, Poole RK. Transcriptional responses of Escherichia coli to S-nitrosoglutathione under defined chemostat conditions reveal major changes in methionine biosynthesis. J Biol Chem 2005 280 : 10065 10072
27. Justino MC, Vicente JB, Teixeira M, Saraiva LM. New genes implicated in the protection of anaerobically grown Escherichia coli against nitric oxide. J Biol Chem 2005 280 : 2636 2643
28. Bergsten G, Samuelsson M, Wullt B, Leijonhufvud I, Fischer H, Svanborg C. PapG-dependent adherence breaks mucosal inertia and triggers the innate host response. J Infect Dis 2004 189 : 1734 1742
29. Dedon PC, Tannenbaum SR. Reactive nitrogen species in the chemical biology of inflammation. Arch Biochem Biophys 2004 423 : 12 22
30. Fang L, Nowicki BJ, Urvil P et al. Epithelial invasion by Escherichia coli bearing Dr fimbriae is controlled by nitric oxide-regulated expression of CD55. Infect Immun 2004 72 : 2907 2914