-
1
-
-
49249152617
-
A new stereospecific cross-coupling by the palladium-catalyzed reaction of 1-alkenylboranes with 1-alkenyl or 1-alkynyl halides
-
Miyaura, N.; Yamada, K.; Suzuki, A. A new stereospecific cross-coupling by the palladium-catalyzed reaction of 1-alkenylboranes with 1-alkenyl or 1-alkynyl halides. Tetrahedron Lett. 1979, 20, 3437-3440.
-
(1979)
Tetrahedron Lett.
, vol.20
, pp. 3437-3440
-
-
Miyaura, N.1
Yamada, K.2
Suzuki, A.3
-
2
-
-
37049107259
-
Stereoselective synthesis of arylated (E)-alkenes by the reaction of alk-1-enylboranes with aryl halides in the presence of palladium catalyst
-
Miyaura, N.; Suzuki, A. Stereoselective synthesis of arylated (E)-alkenes by the reaction of alk-1-enylboranes with aryl halides in the presence of palladium catalyst. J. Chem. Soc. Chem. Commun. 1979, 866-867.
-
(1979)
J. Chem. Soc. Chem. Commun.
, pp. 866-867
-
-
Miyaura, N.1
Suzuki, A.2
-
3
-
-
2042507954
-
Palladium-catalyzed cross-coupling reactions of organoboron compounds
-
Miyaura, N.; Suzuki, A. Palladium-Catalyzed Cross-Coupling Reactions of Organoboron Compounds. Chem. Rev. 1995, 95, 2457-2483.
-
(1995)
Chem. Rev.
, vol.95
, pp. 2457-2483
-
-
Miyaura, N.1
Suzuki, A.2
-
4
-
-
0002812967
-
Organoboron compounds
-
Miyaura, N. Organoboron Compounds. Top. Curr. Chem. 2002, 219, 11-59.
-
(2002)
Top. Curr. Chem.
, vol.219
, pp. 11-59
-
-
Miyaura, N.1
-
6
-
-
0346786657
-
Recent advances in the cross-coupling reactions of organoboron derivatives with organic electrophiles, 1995-1998
-
Suzuki, A. Recent advances in the cross-coupling reactions of organoboron derivatives with organic electrophiles, 1995-1998. J. Organomet. Chem. 1999, 576, 147-168.
-
(1999)
J. Organomet. Chem.
, vol.576
, pp. 147-168
-
-
Suzuki, A.1
-
7
-
-
33646456316
-
Regioselective dicouplings: Application to differentially substituted pyrroles
-
Handy, S. T.; Sabatini, J.J. Regioselective Dicouplings: Application to Differentially Substituted Pyrroles. Org. Lett. 2006, 8, 1537-1537.
-
(2006)
Org. Lett.
, vol.8
, pp. 1537-1537
-
-
Handy, S.T.1
Sabatini, J.J.2
-
8
-
-
36348953849
-
New efficient route to dissymmetric 2,4-Di(het)aryl-pyrido[3,2-d] pyrimidines via regioselective cross-coupling reactions
-
Tikad, A.; Routier, S.; Akssira, M.; Leger, J.-M.; Jarry, C.; Guillaumet, G. New Efficient Route to Dissymmetric 2,4-Di(het)aryl-pyrido[3,2-d]pyrimidines via Regioselective Cross-Coupling Reactions. Org. Lett. 2007, 9, 4673-4676.
-
(2007)
Org. Lett.
, vol.9
, pp. 4673-4676
-
-
Tikad, A.1
Routier, S.2
Akssira, M.3
Leger, J.-M.4
Jarry, C.5
Guillaumet, G.6
-
9
-
-
0033486308
-
Quinoline, quinazoline and acridone alkaloids.
-
Michael, J.P. Quinoline, quinazoline and acridone alkaloids. Nat. Prod. Rep. 1999, 16, 697-709.
-
(1999)
Nat. Prod. Rep.
, vol.16
, pp. 697-709
-
-
Michael, J.P.1
-
10
-
-
49449113807
-
Discovery of 2-chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine (EP128265, MPI-0441138) as a potent inducer of apoptosis with high in Vivo activity
-
Sirisoma, N.; Kasibhatla, S.; Pervin, A.; Zhang, H.; Jiang, S.; Willardsen, J.A.; Anderson, M.B.; Baichwal, V.; Mather, G.G.; Jessing, K.; Hussain, R.; Hoang, K.; Pleiman, C.M.; Tseng, B.; Drewe, J.; Cai, S.X. Discovery of 2-Chloro-N-(4-methoxyphenyl)-N-methylquinazolin-4-amine (EP128265, MPI-0441138) as a Potent Inducer of Apoptosis with High In Vivo Activity. J. Med. Chem. 2008, 51, 4771-4779.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 4771-4779
-
-
Sirisoma, N.1
Kasibhatla, S.2
Pervin, A.3
Zhang, H.4
Jiang, S.5
Willardsen, J.A.6
Anderson, M.B.7
Baichwal, V.8
Mather, G.G.9
Jessing, K.10
Hussain, R.11
Hoang, K.12
Pleiman, C.M.13
Tseng, B.14
Drewe, J.15
Cai, S.X.16
-
11
-
-
40849096342
-
Synthesis and SAR of 1-acetanilide-4-aminopyrazole-substituted quinazolines: Selective inhibitors of Aurora B kinase with potent anti-tumor activity
-
Foote, K.M.; Mortlock, A.A.; Heron, N.M.; Jung, F.H.; Hill, G.B.; Pasquet, G.; Brady, M.C.; Green, S.; Heaton, S.P.; Kearney, S.; Keen, N.J.; Odedra, R.; Wedgea, S.R.; Wilkinsona, R.W. Synthesis and SAR of 1-acetanilide-4-aminopyrazole-substituted quinazolines: Selective inhibitors of Aurora B kinase with potent anti-tumor activity. Bioorg. Med. Chem. Lett. 2008, 18, 1904-1909.
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 1904-1909
-
-
Foote, K.M.1
Mortlock, A.A.2
Heron, N.M.3
Jung, F.H.4
Hill, G.B.5
Pasquet, G.6
Brady, M.C.7
Green, S.8
Heaton, S.P.9
Kearney, S.10
Keen, N.J.11
Odedra, R.12
Wedgea, S.R.13
Wilkinsona, R.W.14
-
12
-
-
40849136472
-
Neutral 5-substituted 4-indazolylaminoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinase
-
Barlaam, B.; Acton, D.G.; Ballard, P.; Bradbury, R.H.; Cross, D.; Ducray, R.; Germain, H.; Hudson, K.; Klinowska, T.; Magnien, F.; Ogilvie, D.J.; Olivier, A.; Ross, H.S.; Smith, R.; Trigwell, C.B.; Vautier, M.; Wright, L. Neutral 5-substituted 4-indazolylaminoquinazolines as potent, orally active inhibitors of erbB2 receptor tyrosine kinase. Bioorg. Med. Chem. Lett. 2008, 18, 1799-1803.
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 1799-1803
-
-
Barlaam, B.1
Acton, D.G.2
Ballard, P.3
Bradbury, R.H.4
Cross, D.5
Ducray, R.6
Germain, H.7
Hudson, K.8
Klinowska, T.9
Magnien, F.10
Ogilvie, D.J.11
Olivier, A.12
Ross, H.S.13
Smith, R.14
Trigwell, C.B.15
Vautier, M.16
Wright, L.17
-
13
-
-
41349085423
-
Synthesis of novel 4,6-disubstituted quinazoline derivatives, their anti-inflammatory and anticancer activity (cytotoxic) against U937 leukemia cell lines
-
Chandrika, P.M.; Yakaiah, T.; Ram Rao, A.R.; Narsaiah, B.; Reddy, N.C.; Sridhar, V.; Rao, J.V. Synthesis of novel 4,6-disubstituted quinazoline derivatives, their anti-inflammatory and anticancer activity (cytotoxic) against U937 leukemia cell lines. Eur. J. Med. Chem. 2008, 43, 846-852.
-
(2008)
Eur. J. Med. Chem.
, vol.43
, pp. 846-852
-
-
Chandrika, P.M.1
Yakaiah, T.2
Ram Rao, A.R.3
Narsaiah, B.4
Reddy, N.C.5
Sridhar, V.6
Rao, J.V.7
-
14
-
-
37549012975
-
Synthesis and antiplasmodial activity of new 4-aryl-2- trichloromethylquinazolines
-
Verhaeghe, P.; Azas, N.; Gasquet, M.; Hutter, S.; Ducros, C.; Laget, M.; Rault, S.; Rathelot, P.; Vanelle, P. Synthesis and antiplasmodial activity of new 4-aryl-2-trichloromethylquinazolines. Bioorg. Med. Chem. Lett. 2008, 18, 396-401.
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 396-401
-
-
Verhaeghe, P.1
Azas, N.2
Gasquet, M.3
Hutter, S.4
Ducros, C.5
Laget, M.6
Rault, S.7
Rathelot, P.8
Vanelle, P.9
-
15
-
-
66749192745
-
Synthesis and in vitro antiplasmodial evaluation of 4-anilino-2- trichloromethylquinazolines
-
Verhaeghe, P.; Azas, N.; Hutter, S.; Castera-Ducros, C.; Laget, M.; Dumètre, A.; Gasquet, M.; Reboul, J.-P.; Rault, S.; Rathelot, P.; Vanelle, P. Synthesis and in vitro antiplasmodial evaluation of 4-anilino-2-trichloromethylquinazolines. Bioorg. Med. Chem. 2009, 17, 4313-4322.
-
(2009)
Bioorg. Med. Chem.
, vol.17
, pp. 4313-4322
-
-
Verhaeghe, P.1
Azas, N.2
Hutter, S.3
Castera-Ducros, C.4
Laget, M.5
Dumètre, A.6
Gasquet, M.7
Reboul, J.-P.8
Rault, S.9
Rathelot, P.10
Vanelle, P.11
-
16
-
-
73849117876
-
Original quinazoline derivatives displaying antiplasmodial properties
-
Kabri, Y.; Azas, N.; Dumètre, A.; Hutter, S.; Laget, M.; Verhaeghe, P.; Gellis, A.; Vanelle, P. Original quinazoline derivatives displaying antiplasmodial properties. Eur. J. Med. Chem. 2010, 45, 616-622.
-
(2010)
Eur. J. Med. Chem.
, vol.45
, pp. 616-622
-
-
Kabri, Y.1
Azas, N.2
Dumètre, A.3
Hutter, S.4
Laget, M.5
Verhaeghe, P.6
Gellis, A.7
Vanelle, P.8
-
17
-
-
34447097175
-
Microwave-assisted synthesis in water as solvent
-
Dallinger, D.; Kappe, C.O. Microwave-Assisted Synthesis in Water as Solvent. Chem. Rev. 2007, 107, 2563-2591.
-
(2007)
Chem. Rev.
, vol.107
, pp. 2563-2591
-
-
Dallinger, D.1
Kappe, C.O.2
-
18
-
-
0041570557
-
Direct synthesis of unprotected 4-aryl phenylalanines via the suzuki reaction under microwave irradiation
-
Gong, Y.; He, W. Direct Synthesis of Unprotected 4-Aryl Phenylalanines via the Suzuki Reaction under Microwave Irradiation. Org. Lett. 2002, 4, 3803-3805.
-
(2002)
Org. Lett.
, vol.4
, pp. 3803-3805
-
-
Gong, Y.1
He, W.2
-
19
-
-
14544289090
-
Microwave-promoted heck coupling using ultralow metal catalyst concentrations
-
Arvela, R.K.; Leadbeater, N.E. Microwave-Promoted Heck Coupling Using Ultralow Metal Catalyst Concentrations. J. Org. Chem. 2005, 70, 1786-1790.
-
(2005)
J. Org. Chem.
, vol.70
, pp. 1786-1790
-
-
Arvela, R.K.1
Leadbeater, N.E.2
-
20
-
-
33646568471
-
Rapid microwave-promoted synthesis of new sulfonylmethylbenzothiazoles in water
-
DOI 10.1039/b601452f
-
Gellis, A.; Boufatah, N.; Vanelle, P. Rapid microwave-promoted synthesis of new sulfonylmethylbenzothiazoles in water. Green Chem. 2006, 8, 483-487. (Pubitemid 43725939)
-
(2006)
Green Chemistry
, vol.8
, Issue.5
, pp. 483-487
-
-
Gellis, A.1
Boufatah, N.2
Vanelle, P.3
-
21
-
-
0035931419
-
Microwave mediated palladium-catalysed reactions on potassium fluoride/alumina without use of solvent
-
Villemin, D.; Caillot, F. Microwave mediated palladium-catalysed reactions on potassium fluoride/alumina without use of solvent. Tetrahedron Lett. 2001, 42, 639-642.
-
(2001)
Tetrahedron Lett.
, vol.42
, pp. 639-642
-
-
Villemin, D.1
Caillot, F.2
-
22
-
-
0035742525
-
Solvent-free accelerated organic syntheses using microwaves
-
Varma, R.S. Solvent-free accelerated organic syntheses using microwaves. Pure Appl. Chem. 2001, 73, 193-198.
-
(2001)
Pure Appl. Chem.
, vol.73
, pp. 193-198
-
-
Varma, R.S.1
-
23
-
-
13244273376
-
Synthesis of phosphonium salts under microwave activation - Leaving group and phosphine substituents effects
-
Cvengros, A.; Toma, S.; Marque, S.; Loupy, A. Synthesis of phosphonium salts under microwave activation - Leaving group and phosphine substituents effects. Can. J. Chem. 2004, 82, 1365-1371.
-
(2004)
Can. J. Chem.
, vol.82
, pp. 1365-1371
-
-
Cvengros, A.1
Toma, S.2
Marque, S.3
Loupy, A.4
-
24
-
-
17744385778
-
Microwave-assisted Suzuki reactions in a continuous flow capillary reactor
-
He, P.; Haswell, S.J.; Fletcher, D.I. Microwave-assisted Suzuki reactions in a continuous flow capillary reactor. Appl. Catal. A Gen. 2004, 274, 111-114.
-
(2004)
Appl. Catal. A Gen.
, vol.274
, pp. 111-114
-
-
He, P.1
Haswell, S.J.2
Fletcher, D.I.3
-
25
-
-
33947731107
-
Microwave assisted asymmetric Suzuki-Miyaura and Negishi cross-coupling reactions: Synthesis of chiral binaphthalenes
-
Genov, M.; Almorin, A.; Espinet, P. Microwave assisted asymmetric Suzuki-Miyaura and Negishi cross-coupling reactions: Synthesis of chiral binaphthalenes. Tetrahedron Asymmetry 2007, 18, 625-627.
-
(2007)
Tetrahedron Asymmetry
, vol.18
, pp. 625-627
-
-
Genov, M.1
Almorin, A.2
Espinet, P.3
-
26
-
-
68349088939
-
Synthesis of original 2-substituted 4-arylquinazolines by microwave-irradiated Suzuki-Miyaura cross-coupling reactions
-
Kabri, Y.; Gellis, A.; Vanelle, P. Synthesis of original 2-substituted 4-arylquinazolines by microwave-irradiated Suzuki-Miyaura cross-coupling reactions. Eur. J. Org. Chem. 2009, 4059-4066.
-
(2009)
Eur. J. Org. Chem.
, pp. 4059-4066
-
-
Kabri, Y.1
Gellis, A.2
Vanelle, P.3
-
27
-
-
0030039957
-
Trialkylalanes in palladium-catalyzed chemo- and regioselective alkylations
-
Mangalagiu, I.; Benneche, T.; Undheim, K. Trialkylalanes in palladium-catalyzed chemo- and regioselective alkylations. Tetrahedron Lett. 1996, 37, 1309-1312.
-
(1996)
Tetrahedron Lett.
, vol.37
, pp. 1309-1312
-
-
Mangalagiu, I.1
Benneche, T.2
Undheim, K.3
-
28
-
-
34948830110
-
A concise synthesis of quinazolinone TGF-β RI inhibitor through one-pot three-component Suzuki-Miyaura/etherification and imidate-amide rearrangement reactions
-
Li, H.; Wang, Y.; McMillen, W.T.; Chatterjee, A.; Toth, J.E.; Mundla, S.R.; Voss, M.; Boyer, R.D.; Sawyer, J.S. A concise synthesis of quinazolinone TGF-β RI inhibitor through one-pot three-component Suzuki-Miyaura/ etherification and imidate-amide rearrangement reactions. Tetrahedron 2007, 63, 11763-11770.
-
(2007)
Tetrahedron
, vol.63
, pp. 11763-11770
-
-
Li, H.1
Wang, Y.2
McMillen, W.T.3
Chatterjee, A.4
Toth, J.E.5
Mundla, S.R.6
Voss, M.7
Boyer, R.D.8
Sawyer, J.S.9
-
29
-
-
0037112673
-
Palladium-catalyzed coupling reactions of aryl chlorides
-
Littke, A.F.; Fu, G.C. Palladium-Catalyzed Coupling Reactions of Aryl Chlorides. Angew. Chem. Int. Ed. 2002, 41, 4176-4211.
-
(2002)
Angew. Chem. Int. Ed.
, vol.41
, pp. 4176-4211
-
-
Littke, A.F.1
Fu, G.C.2
-
30
-
-
67349136549
-
Microwave-assisted synthesis in aqueous medium of new quinazoline derivatives as anticancer agent precursors
-
Kabri, Y.; Gellis, A.; Vanelle, P. Microwave-assisted synthesis in aqueous medium of new quinazoline derivatives as anticancer agent precursors. Green Chem. 2009, 11, 201-208.
-
(2009)
Green Chem.
, vol.11
, pp. 201-208
-
-
Kabri, Y.1
Gellis, A.2
Vanelle, P.3
-
32
-
-
68849083988
-
-
[Chem. Abstr. 2007, 147, 427370].
-
(2007)
Chem. Abstr.
, vol.147
, pp. 427370
-
-
-
33
-
-
0028816884
-
Electron transfer reactivity in 5-nitrouracil series
-
Crozet, M.P.; Gellis, A.; Pasquier, C.; Vanelle, P.; Aune, J.-P. Electron transfer reactivity in 5-nitrouracil series. Tetrahedron Lett. 1995, 36, 525-528.
-
(1995)
Tetrahedron Lett.
, vol.36
, pp. 525-528
-
-
Crozet, M.P.1
Gellis, A.2
Pasquier, C.3
Vanelle, P.4
Aune, J.-P.5
-
35
-
-
4644223893
-
Preparation and resolution of a modular class of axially chiral quinazoline-containing ligands and their application in asymmetric rhodium-catalyzed olefin hydroboration
-
Conolly, D.J.; Lacey, P.M.; Mc Carthy, M.; Saunders, C.P.; Carroll, A.-M.; Goddard, R.; Guiry, P.J. Preparation and Resolution of a Modular Class of Axially Chiral Quinazoline-Containing Ligands and Their Application in Asymmetric Rhodium-Catalyzed Olefin Hydroboration. J. Org. Chem. 2004, 69, 6572-6589.
-
(2004)
J. Org. Chem.
, vol.69
, pp. 6572-6589
-
-
Conolly, D.J.1
Lacey, P.M.2
McCarthy, M.3
Saunders, C.P.4
Carroll, A.-M.5
Goddard, R.6
Guiry, P.J.7
-
36
-
-
43849091460
-
Suzuki-Miyaura cross-coupling of α-phosphoryloxy enol ethers with arylboronic acids
-
Pedzisa, L.; Vaughn, I.W.; Pongdee, R. Suzuki-Miyaura cross-coupling of α-phosphoryloxy enol ethers with arylboronic acids. Tetrahedron Lett. 2008, 49, 4142-4144.
-
(2008)
Tetrahedron Lett.
, vol.49
, pp. 4142-4144
-
-
Pedzisa, L.1
Vaughn, I.W.2
Pongdee, R.3
|