HE4, a novel marker for epithelial ovarian cancer: Evaluation of analytical performances;HE4, un nouveau marqueur des cancers épithéliaux ovariens: Évaluation des performances analytiques

Annales de Biologie Clinique

Volumn 68, Issue 3, 2010, Pages 325-329

  Lamy, Pierre Jean ^a   Roques, Sylvie ^a   Viglianti, Cathy ^a   Fabbro, Michel ^b   Montels, Frédéric ^a  

^a Laboratoire de Biologie Specialisée et d'Oncogenetique   (France)

^b CENTRE VAL D AURELLE   (France)

Author keywords

CA125; HE4; Ovarian cancer; Tumor markers

Indexed keywords

DEFB126 PROTEIN, HUMAN; EPIDIDYMAL SECRETORY PROTEIN;

ARTICLE; ENZYME LINKED IMMUNOSORBENT ASSAY; EVALUATION; FEMALE; GENETIC MARKER; GENETICS; HUMAN; OVARY TUMOR;

ENZYME-LINKED IMMUNOSORBENT ASSAY; EPIDIDYMAL SECRETORY PROTEINS; FEMALE; GENETIC MARKERS; HUMANS; OVARIAN NEOPLASMS;

EID: 77952838306     PISSN: 00033898     EISSN: 19506112     Source Type: Journal    
DOI: 10.1684/abc.2010.0435     Document Type: Article

References (9)

1. NIH consensus conference. Ovarian cancer. Screening, treatment, and follow-up. NIH Consensus Development Panel on Ovarian Cancer. JAMA 1995; 273: 491-497
2. Munkarah A, Chatterjee M, Tainsky MA. Update on ovarian cancer screening. Curr Opin Obstet Gynecol 2007; 19: 22-26
3. Galgano MT, Hampton GM, Frierson Jr HF. Comprehensive analysis of HE4 expression in normal and malignant human tissues. Mod Pathol 2006; 19: 847-853
4. Hellstrom I, Raycraft J, Hayden-Ledbetter M, Ledbetter JA, Schummer M, McIntosh M, et al. The HE4 (WFDC2) protein is a biomarker for ovarian carcinoma. Cancer Res 2003; 63: 3695-3700
5. Moore RG, Brown AK, Miller MC, Badgwell D, Lu Z, Allard WJ, et al. Utility of a novel serum tumor biomarker HE4 in patients with endometrioid adenocarcinoma of the uterus. Gynecol Oncol 2008; 110: 196-201.
6. Moore RG, McMeekin DS, Brown AK, DiSilvestro P, Miller MC, Allard WJ, et al. A novel multiple marker bioassay utilizing HE4 and CA125 for the prediction of ovarian cancer in patients with a pelvic mass. Gynecol Oncol 2009; 112: 40-46
7. Scholler N, Crawford M, Sato A, Drescher CW, O'Briant KC, Kiviat N, et al. Bead-based ELISA for validation of ovarian cancer early detection markers. Clin Cancer Res 2006; 12: 2117-2124
8. Havrilesky LJ, Whitehead CM, Rubatt JM, Cheek RL, Groelke J, He Q, et al. Evaluation of biomarker panels for early stage ovarian cancerdetection and monitoring for disease recurrence. Gynecol Oncol 2008; 110: 374-382
9. Allard J, Somer E, Theil R, Moore RG. Use of a novel biomarker for monitoring patients with epithelial ovarian cancer. J Clin Oncol 2008; 26: 5535.