The role of lipoprotein(a) in the formation of arterial plaques, stenoses and occlusions

Canadian Journal of Cardiology

Volumn 26, Issue SUPPLA, 2010, Pages

  Spence, J David ^a  

^a ROBARTS RESEARCH INSTITUTE   (Canada)

Author keywords

Atherosclerosis; Lipoprotein(a); Lp(a); Occlusion; Plaque; Stenosis

Indexed keywords

LIPOPROTEIN A; PLASMINOGEN;

ARTICLE; ATHEROSCLEROSIS; CARDIOVASCULAR RISK; CAROTID ARTERY OBSTRUCTION; CAROTID ARTERY THROMBOSIS; FIBRINOLYSIS; HUMAN; PROTEIN FUNCTION; RISK FACTOR; ECHOGRAPHY; METABOLISM; PATHOLOGY; REVIEW;

CAROTID STENOSIS; HUMANS; LIPOPROTEIN(A); RISK FACTORS;

EID: 77952788235     PISSN: 0828282X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0828-282X(10)71060-6     Document Type: Article

References (23)

1. Berglund L, Ramakrishnan R. Lipoprotein(a): An elusive cardiovascular risk factor. Arterioscler Thromb Vasc Biol 2004;24:2219-26.
2. Koschinsky ML. Lipoprotein(a) and atherosclerosis: New perspectives on the mechanism of action of an enigmatic lipoprotein. Curr Atheroscler Rep 2005;7:389-95.
3. Danesh J, Collins R, Peto R. Lipoprotein(a) and coronary heart disease. Meta-analysis of prospective studies. Circulation 2000;102:1082-5.
4. Koschinsky ML, Marcovina SM. Structure-function relationships in apolipoprotein(a): Insights into lipoprotein(a) assembly and pathogenicity. Curr Opin Lipidol 2004;15:167-74.
5. Koschinsky ML. Lipoprotein(a) and the link between atherosclerosis and thrombosis. Can J Cardiol 2004;20(Suppl B):37B-43B.
6. Vuckovic B, Deric M. Lipoprotein(a): A link between thrombogenesis and atherogenesis. Med Pregl 2007;60:37-41.
7. Glagov S, Weisenberg E, Zarins CK, Stankunavicius R, Kolettis GJ. Compensatory enlargement of human atherosclerotic coronary arteries. N Engl J Med 1987;316:1371-5.
8. Caro CG. Discovery of the role of wall shear in atherosclerosis. Arterioscler Thromb Vasc Biol 2009;29:158-61.
9. Spence JD. Cerebral consequences of hypertension: Where do they lead? J Hypertens Suppl 1996;14:S139-S145.
10. Ziegler T, Bouzourene K, Harrison VJ, Brunner HR, Hayoz D. Influence of oscillatory and unidirectional flow environments on the expression of endothelin and nitric oxide synthase in cultured endothelial cells. Arterioscler Thromb Vasc Biol 1998;18:686-92.
11. Korshunov VA, Schwartz SM, Berk BC. Vascular remodeling: Hemodynamic and biochemical mechanisms underlying Glagov's phenomenon. Arterioscler Thromb Vasc Biol 2007;27:1722-8.
12. Hahn C, Schwartz MA. The role of cellular adaptation to mechanical forces in atherosclerosis. Arterioscler Thromb Vasc Biol 2008;28:2101-7.
13. Spence JD. Ultrasound measurement of carotid plaque: Uses in patient management, genetic research and evaluation of new therapies. Nat Clin Pract Neurol 2006;2:611-9.
14. Ainsworth CD, Blake CC, Tamayo A, Beletsky V, Fenster A, Spence JD. 3D ultrasound measurement of change in carotid plaque volume: A tool for rapid evaluation of new therapies. Stroke 2005;36:1904-9.
15. Egger M, Spence JD, Fenster A, Parraga G. Validation of 3D ultrasound vessel wall volume: An imaging phenotype of. Ultrasound Med Biol 2007;33:905-14.
16. Spence JD. Lipoprotein(a): Involved in events, but not burden of atherosclerotic disease? Stroke 2006;37:1350-1.
17. Klein JH, Hegele RA, Hackam DG, Koschinsky ML, Huff MW, Spence JD. Lipoprotein(a) is associated differentially with carotid stenosis, occlusion, and total plaque area. Arterioscler Thromb Vasc Biol 2008;28:1851-6.
18. Spence JD, Barnett PA, Bulman DE, Hegele RA. An approach to ascertain probands with a non traditional risk factor for carotid atherosclerosis. Atherosclerosis 1999;144:429-34.
19. Meinertz H, Nilausen K, Hilden J. Alcohol-extracted, but not intact, dietary soy protein lowers lipoprotein(a) markedly. Arterioscler Thromb Vasc Biol 2002;22:312-6.
20. Anderson JL. Lipoprotein-associated phospholipase A2: An independent predictor of coronary artery disease events in primary and secondary prevention. Am J Cardiol 2008;101:23F-33F.
21. Rudd JH, Warburton EA, Fryer TD, et al. Imaging atherosclerotic plaque inflammation with [18F]-fluorodeoxyglucose positron emission tomography. Circulation 2002;105:2708-11.
22. Pepys MB. CRP or not CRP? That is the question. Arterioscler Thromb Vasc Biol 2005;25:1091-4.
23. Zacho J, Tybjaerg-Hansen A, Jensen JS, Grande P, Sillesen H, Nordestgaard BG. Genetically elevated C-reactive protein and ischemic vascular disease. N Engl J Med 2008;359:1897-908.