Sensitive LC-MS-MS method for the determination of tiopronin in human plasma

Biomedical Chromatography

Volumn 24, Issue 6, 2010, Pages 655-662

  Jiang, Bo ^a   Xu, Yu ^a   Xu, Fang ^a   Sun, Junjie ^a   Li, Na ^a   Luo, Yanan ^a   Guo, Qingxiang ^a  

^a UNIVERSITY OF SCIENCE AND TECHNOLOGY OF CHINA   (China)

Author keywords

Human plasma; LC MS MS; Pharmacokinetic application; Tiopronin

Indexed keywords

AMINO ACIDS; ELECTROSPRAY IONIZATION; PHASE INTERFACES; PLASMA (HUMAN);

DITHIOTHREITOL; HUMAN PLASMAS; INTERNAL STANDARDS; L-CYSTEINE; LC-MS-MS; LC.MS/MS; PHARMACOKINETIC APPLICATION; PLASMA SAMPLES; STABILISER; TIOPRONIN;

PHARMACOKINETICS;

ACETIC ACID ETHYL ESTER; CYSTEINE; DITHIOTHREITOL; FORMIC ACID; FUDOSTEINE; METHANOL; TIOPRONIN; WATER;

ACCURACY; AREA UNDER THE CURVE; ARTICLE; CALIBRATION; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG STABILITY; DRUG STORAGE; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; HUMAN; HUMAN EXPERIMENT; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; MAXIMUM PLASMA CONCENTRATION; NORMAL HUMAN; SENSITIVITY ANALYSIS; SENSITIVITY AND SPECIFICITY; TANDEM MASS SPECTROMETRY; VALIDATION PROCESS;

EID: 77952785081     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.1342     Document Type: Article

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